Abstract: A brake system for a driving simulator, the brake system comprising a master cylinder chamber and a slave cylinder chamber which are arranged in fluid communication via a hydraulic system. The master cylinder chamber comprising a master cylinder piston which is mechanically connected to a brake pedal such that movement of the brake pedal results in translation of the master cylinder piston along the axis of said master cylinder chamber. The hydraulic system comprising a pressure module which is arranged such that it divides the hydraulic system into a master side in fluid communication with the master cylinder chamber and a slave side in fluid communication with the slave cylinder chamber. The pressure system is adapted to intermittently increase and decrease the pressure in the hydraulic system such that tactile feedback is provided to the brake pedal.

Abstract: A device configured to be mounted on a mechanical component and to measure an axial load exerted on the mechanical component, the device including a ring provided with an inner cylindrical surface and with an outer opposite cylindrical surface, the inner and outer cylindrical surfaces delimiting the radial thickness of the ring. The device further provides at least one optical sensing fiber disposed in a first circumferential groove provided on one of the outer and inner cylindrical surfaces of the ring.

Abstract: A computer-implemented method for civil engineering is described that includes obtaining a watershed segmentation of a terrain. The watershed segmentation includes basins. The method further includes merging first basins of the watershed segmentation that each verify a smallness criterion, each with a second basin downstream to the first basin.

Abstract: A power tool including a primary housing and a motor assembly connectable to a cutting tool. The motor assembly is configured to drive the cutting tool. A secondary housing is mounted within the primary housing. At least one first dampening system is coupled between the primary housing and the motor assembly. At least one second dampening system is coupled between the primary housing and the secondary housing. The at least one first dampening system and the at least one second dampening system are configured to reduce vibrations in the secondary housing generated by the motor assembly.

Abstract: An irreversible electroporation (IRE) method includes placing multiple electrodes of a catheter in contact with tissue of an organ. Bipolar IRE pulses are generated. The tissue is ablated by applying the bipolar IRE pulses to pairs of the electrodes, in accordance with an order in which successive activations of a given electrode-pair are interleaved with activation of at least one other electrode-pair, and are spaced in time by at least a predefined duration.

Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.

Abstract: Described herein are methods and system for electronic workflow management having a central server that periodically scans data accessible to multiple computers and data interacted with by different users to generate a nodal data structure comprising of interrelated nodes where each node corresponds to a workflow component, such as files, messages, tasks, and the like. The server then executes various analytical protocols to identify and link/merge nodes corresponding to related content. Upon receiving a set of notifications for a user, the server augments the notifications with data retrieved/derived from the nodal data structure. The server then prioritizes outputting the notifications based on their respective contextualized data and/or based on attributes received from the user.

Abstract: A method includes determining an operational condition associated with an unmanned aerial vehicle (UAV). The method includes, responsive to determining the operational condition, causing the UAV to perform a pre-flight check. The pre-flight check includes hovering the UAV above a takeoff location. The pre-flight check includes, while hovering the UAV, moving one or more controllable components of the UAV in accordance with a predetermined sequence of movements. The pre-flight check includes obtaining, by one or more sensors of the UAV, sensor data indicative of a flight response of the UAV to moving the one or more controllable components while hovering the UAV. The pre-flight check includes comparing the sensor data to expected sensor data associated with an expected flight response to the predetermined sequence of movements while hovering the UAV. The pre-flight check includes, based on comparing the sensor data to the expected sensor data, evaluating performance of the UAV.

Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.

Abstract: Apparatus and method for operating a machine with a tool, wherein the method includes capturing at least one operating data point for the machine and/or the tool, calculating at least one estimate value from the at least one operating data point based on an ML model, determining an anomaly in the form of a discrete-time anomaly value based on the at least one estimate value via a comparison with a predetermined comparison value for the at least one estimate and detection of a match for the estimate comparison, storing the discrete-time anomaly value in a memory and aggregating the trend in the anomaly value over time to form a smoothed anomaly value, comparing the smoothed anomaly value with at least one predetermined comparison value for the anomaly and detecting a match for the anomaly comparison, and outputting a control operation to the machine based on the smoothed anomaly value.

Abstract: A control system providing a control signal to an energy storage system to reduce power variability of an energy generation system. The energy storage system is coupled to the power output of the energy generation system and configured to at least one of receive and provide electrical power in response to the control signal. The control system includes a monitoring unit to monitor the power output and to provide a respective monitoring signal. The control system further includes a control signal generation unit to generate the control signal from the monitoring signal, and implement a filtering unit that has a band pass response. The filtering unit passes a predetermined frequency band of the monitoring signal and the control signal generation unit is configured to generate the control signal in the frequency band to compensate power variations of the power output of the energy generation system in the frequency band.

Abstract: An access control terminal (1), comprising an electronic circuit (11) and an ultra-wide-band transceiver (10) connected to the electronic circuit (11) wherein the electronic circuit (11) exchanges messages with a mobile device (2) to determine a distance (d) of the mobile device (2) from the access control terminal (1), and to transmit to the mobile device (2) one or more update messages configured to update access rights data in the mobile device (2), if the mobile device (2) is within the pre-determined proximity range (P).

Abstract: A method of controlling the ionic conductivity of a polymer member, including providing a plurality of particles of bi-doped garnet, dispersing the plurality of particles of bi-doped garnet in a PEO matrix to yield a polymer member, nucleating spherulites at bi-doped garnet particle sites, and growing spherulites to a critical density to provide ionic conductivity pathways throughout the polymer member.

Abstract: A door module for a vehicle door, having at least one region, which is substantially formed by an organosheet. In particular, the door module has at least two different types of organosheet, by means of which different regions of the door module are formed.

Abstract: A method for measuring autophagosome flux is provided. The autophagosome pool size in a single cell is quantified, where the pool size is the total number of autophagosomes in the cell. Fusion between the autophagosomes and lysosomes in the cell is then inhibited. The autophagosome pool size is quantified over one or more time points after fusion has been inhibited, and the autophagosome flux is calculated as the initial rate of change of the autophagosome pool size at the time point after fusion has been inhibited. The method can be used to determine basal autophagosome flux, whether a cell is diseased or dysfunctional, or to diagnose a subject with a disease, disorder or dysfunction. The transition time, the time required to clear an autophagosome pool, can also be derived from the autophagosome flux. A molecule can also be characterized according to its ability to modulate autophagosome flux in a cell.

Abstract: An aircraft headlight comprises at least one light source and an integrated, single-piece optical structure. The integrated, single-piece optical structure includes a light transmissive protective cover portion, forming an outer light emission surface of the aircraft headlight, and at least one reflector portion, arranged for directing light that is emitted by the at least one light source through the light transmissive protective cover portion.

Abstract: A tow attachment for a watercraft is disclosed. The tow attachment is configured to attach a tow rope to the watercraft, and has a first part and a second part that is connected to the first part by a connecting portion. The first part is configured for rigid connection to the watercraft, and the second part is configured to attach to the tow rope. The second part disconnects from the first part about the connecting portion in response to the tow rope applying a load above a predetermined load to the second part. A tow pylon assembly having a tow pylon and the tow attachment connected to the tow pylon is also disclosed. A watercraft with the tow attachment and a watercraft with the tow pylon assembly are also disclosed.