Patents by Inventor Andre Malanda

Andre Malanda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of N-(heteroaryl)-1-heteroaryl-1H-indole-2-carboxamides, preparation thereof and therapeutic use thereof
    Publication number: 20090306143
    Abstract: The invention relates to compounds of formula (I): Wherein X1, X2, X3, X4, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.
    Type: Application
    Filed: July 17, 2009
    Publication date: December 10, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, André MALANDA, Christian MALOIZEL
  • Derivatives of pyrrolopyridine-2-carboxamides, preparation thereof and therapeutic application thereof
    Publication number: 20090298865
    Abstract: The invention relates to compounds of formula (I): Wherein n, the pyrrolopyridine core, X, Y and W are as described herein. The invention also relates to a preparation method and to a therapeutic application.
    Type: Application
    Filed: July 17, 2009
    Publication date: December 3, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • N-(heteroaryl)-1H-indole-2-carboxamide derivatives and their use as vanilloid TRPVreceptor ligands
    Patent number: 7557134
    Abstract: The invention concerns therapeutic uses of compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation among others as disclosed and specifically claimed.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: July 7, 2009
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • N-(AMINOHETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
    Publication number: 20090156809
    Abstract: The invention relates to compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z1, Z2, Z3, Z4, Ra and Rb are as defined herein. The invention also relates to process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Application
    Filed: January 23, 2009
    Publication date: June 18, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof
    Publication number: 20090156573
    Abstract: The invention concerns compounds of general formula (I): Wherein n, X1, X2, X3, X4, Y, Z, Z1, Z2, Z3 and Z4 are as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.
    Type: Application
    Filed: January 26, 2009
    Publication date: June 18, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA, David MACHNIK, Catherine GILLE
  • TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE
    Publication number: 20090042873
    Abstract: The invention concerns tricyclic N-heteroarylcarboxamide derivatives containing a benzimidazole unit of general formula (I): Wherein A, P, Y, R1, R2 and R3 are as defined herein. The invention also concerns a method of preparing the compounds and their therapeutic use.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 12, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Luc EVEN, Catherine GILLE, Andre MALANDA, David MACHNIK, Nathalie RAKOTOARISOA
  • N-(HETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS VANILLOID TRPV1 RECEPTOR LIGANDS
    Publication number: 20080255131
    Abstract: The invention concerns therapeutic uses of compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation among others as disclosed and specifically claimed.
    Type: Application
    Filed: June 20, 2008
    Publication date: October 16, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • -(heteroaryl)-1-indole-2-carboxamide derivatives and their use as vanilloid TRPV1 receptor ligands
    Patent number: 7407950
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: August 5, 2008
    Assignee: Sanofi-Aventis
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda
  • N-(Heteroaryl)-1-heteroarylalkyl-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof
    Publication number: 20080146646
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Y and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Application
    Filed: January 8, 2008
    Publication date: June 19, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • N-(ARYLALKYL)-1H-PYRROLOPYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080125459
    Abstract: The invention concerns compounds of general formula (I), wherein n, the pyrrolopyridine ring, X, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. The invention also concerns a method for preparing said compounds and their therapeutic use.
    Type: Application
    Filed: January 8, 2008
    Publication date: May 29, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent DUBOIS, Yannick EVANNO, Andre MALANDA
  • N-(HETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS VANILLOID TRPV1 RECEPTOR LIGANDS
    Publication number: 20070259946
    Abstract: The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation.
    Type: Application
    Filed: June 20, 2007
    Publication date: November 8, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Laurent Dubois, Yannick Evanno, Andre Malanda