Abstract: Model-based predictive control (MPC) of a motor vehicle involves an MPC algorithm, which comprises a high level solver module to calculate a high level longitudinal trajectory for an upcoming route segment, according to which the motor vehicle is to travel within a route-based high level prediction horizon. The high level longitudinal trajectory is sent to a tracker solver module in the MPC algorithm as an input value, which calculates a tracker longitudinal trajectory on the basis of the high level longitudinal trajectory, according to which the motor vehicle is to travel within the time-based tracker prediction horizon, wherein the tracker prediction horizon is shorter than the high level prediction horizon, such that the tracker prediction horizon only covers a portion of the high level prediction horizon.

Abstract: The invention relates to novel compounds of the formula (I) in which the R1, R2a, R2b, R3, A1, A2, A3, A4, A5 and n radicals are each as defined above, to the use thereof as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for preparation thereof.

Abstract: According to the invention, there is provided a solid pharmaceutical composition formulation for nasal delivery of an opioid antagonist, comprising a pharmacologically-effective amount of an opioid antagonist and a pharmaceutically-acceptable carrier. The compositions are preferably in the form of a powder produced by spray-drying, which are subsequently loaded into single use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include disaccharides (e.g. lactose or trehalose) and dextrins (e.g. cyclodextrins or maltodextrins), preferably spray-dried together in combination. Compositions may further comprise an alkyl saccharide, preferably a sucrose ester, such as sucrose monolaurate. The compositions and applicators may be employed in the treatment of opioid overdose in subjects.

Abstract: A processor unit (3) for model-based predictive control of a vehicle (1) taking into account an arrival time factor is configured to calculate a trajectory for the vehicle (1) based at least in part on at least one arrival time factor, with the trajectory including an entire route (20) to a specified destination (19) at which the vehicle (1) is to arrive, and with the at least one arrival time factor influencing an arrival time of the vehicle (1) at the specified destination (19). Additionally, the processor unit (3) is configured to optimize a section of the trajectory for the vehicle (1) for a sliding prediction horizon by executing a model-based predictive control (MPC) algorithm (13), where the MPC algorithm (13) includes a longitudinal dynamic model (14) of a drive train (7) of the vehicle (1) and a cost function (15) to be minimized.

Abstract: Described herein are cyclic peptides targeting fibroblast activation protein (FAP), and their incorporation into compounds for radioligand imaging and therapies, as well as methods and/or uses of such compounds for the imaging, treatment and/or prevention of FAP-implicated diseases and disorders.

Abstract: A plug connector housing for a plug connector, having a main body and a latching installation. The latching installation has a first connection portion integrally connecting the latching mechanism to the main body. A void extends along a longitudinal axis on the main body and is at least in portions formed between the latching installation and the main body. The plug connector housing furthermore has first and second protective elements which extend in each case integrally from the main body. The latching installation is disposed between the protective elements, wherein each of the protective elements in at least one covered region covers the void in a transverse direction. Each of the protective elements moreover configures at least one access region in which the void is accessible along the transverse direction. Each of the covered regions faces a respective access region of the respective other protective element along the transverse direction.

Abstract: A dispensing system with a dispense head and at least one container. The dispense head is connectable to a container opening of the container by means of a screw connection, so that stored material is dispensable from or suppliable to the container by means of the dispense head. There is an actuating ring on the dispense head, wherein the screw connection is established by rotating the actuating ring in a closure direction. The screw connection is released by rotating the actuating ring in a release direction. The actuating ring has an overload protection by means of which an effective closure torque is limited to a limit closure torque when the screw connection is established.

Abstract: A dispensing system (1) for a container (2) having a dip tube (5) and being designed for holding stored goods. The dispensing system (1) further has a dispense head (4) which can be fastened to the dip tube (5) so that liquid (3) can be dispensed from the container (2) or liquid (3) can be supplied to the container (2) via the dip tube (5) and the dispense head (4). The dip tube (5) has connection means with a multi-start thread.

Abstract: An arrangement having a coupling connection comprising two coupling parts. The coupling parts can be connected by means of a screw connection and form a fluid channel. On the first coupling part there is a multi-start thread as a connection means as part of the screw connection. On the second coupling part there is a multi-start mating thread as a connection means as a further part of the screw connection.

Abstract: The present invention relates to anti-HLA-G antibodies and methods of using the same.

Abstract: The disclosure relates to a rotary atomizer for applying a spray jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that the construction dimensions of the rotary atomizer are coordinated in such a way that the air pressure at the outlet opening of the paint nozzle during operation is lower than the air pressure in the nozzle chamber of the bell cup and in the external rinsing channels in order to prevent a backflow of the coating agent from the outlet opening of the paint nozzle backwards in the direction of the nozzle chamber due to the pressure difference.

Abstract: An extension device for one or more automation devices in an industrial system is provided. Industrial data processing units capable of performing data processing based on one or more artificial neural networks are provided. To enable and/or accelerate one or more computations in an industrial system, thereby simplifying integration of artificial intelligence into the industrial system, and to simplify data exchange between an extension device capable of processing data using artificial intelligence and an automation device, one or more results of the one or more computations are obtained. The results indicate one or more states of the industrial system. The one or more results are provided via a process state model shared with the automation device to monitor and/or control the industrial system.

Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: A route planning system configured to create a route plan of a forage harvesting process chain. The forage harvesting process chain comprises a plurality of agricultural work machines which perform a forage harvesting process in a predetermined order. The forage harvesting process comprises successive process steps with each process step being performed by a number of the plurality of agricultural work machines. The route planning system is further configured to generate a common route plan for the plurality of agricultural work machines of the forage harvesting process chain and/or an individualized route plan for each agricultural work machine of the plurality of agricultural work machines.

Abstract: An electrical contact element (3) is formed from a stamped and bent part and/or from a deep-drawn metal component (1). The electrical contact element (3) has a contact area (6) having an end-face contact surface (7) designed for electrical and mechanical contacting with an electrical mating contact element. The electrical contact element (3) also has a support area (8), which is arranged on a side of the contact area (6) facing away from the end-face contact surface (7) and is designed so as to mechanically support the contact area (6). It is provided that the contact area (6) is integrally connected to the support area (8) via a primary connecting section (9).

Abstract: Techniques for generating unregistered internet domain names using machine learning (e.g., neural networks) are presented. The techniques can include identifying, using an electronic processor, a subset of registered domain names having at least one specified characteristic, vectorizing, using an electronic processor, a training subset of domain names in the subset of registered domain names to obtain a set of vectors, training, using an electronic processor, a machine learning algorithm with the set of vectors to produce a trained machine learning model, generating, using an electronic processor, at least one output domain name by the trained machine learning model, and outputting the at least one output domain name.

Abstract: The disclosure relates to a bell cup for a rotary atomizer for painting components, having the following features: a hub for rotatably mounting the bell cup on the rotary atomizer, so that the bell cup is rotatable about an axis of rotation, an annular circumferential spraying edge for spraying the paint in the form of a spray jet, and a circumferential outer lateral surface which widens along the axis of rotation in the distal direction towards the spraying edge, The disclosure provides that the outer lateral surface of the bell cup is divided into different sections, which are angled differently. Furthermore, the disclosure comprises a rotary atomizer with such a bell cup, a painting installation and a corresponding painting method.

Abstract: There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof, in associative admixture with particles comprising a weak acid, or particles comprising weakly-acidic buffer forming materials. The composition may further comprise a disintegrant and/or particles of a pharmacologically-effective amount of naloxone, or a pharmaceutically-acceptable salt thereof. The compositions are useful in the treatment of opioid dependency/addiction and/or pain.

Abstract: The disclosure relates to a rotary atomizer for applying a spray jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that the construction dimensions of the rotary atomizer are coordinated in such a way that the air pressure at the outlet opening of the paint nozzle during operation is lower than the air pressure in the nozzle chamber of the bell cup and in the external rinsing channels in order to prevent a backflow of the coating agent from the outlet opening of the paint nozzle backwards in the direction of the nozzle chamber due to the pressure difference.

Abstract: A layer of a chalcogenide material can be etched by providing a wafer having a layer of the chalcogenide material to a processing chamber, heating the wafer to a first temperature, modifying a surface of the layer of chalcogenide material by flowing a first chemical species comprising a fluoride or a chloride onto the wafer to create a modified layer of chalcogenide material while the wafer is at the first temperature, and removing the modified layer of chalcogenide material, without using a plasma, by flowing a second chemical species comprising a compound with a center atom that is aluminum, boron, silicon, or germanium, and with at least one chlorine, onto the wafer.