Abstract: Disclosed herein is a composition comprising: an amorphous solid dispersion (ASD) comprising nilotinib and at least one polymeric stabilizing and matrix-forming component; and at least one solid organic acid in admixture with the ASD, and uses thereof in the treatment of proliferative disorder.

Abstract: A confinement ring for use in a process chamber includes a tubular extension that is configured to surrounds a process region in the process chamber. An upper end of the tubular extension is configured to connect to a showerhead of the process chamber and a lower end that is configured to extend into the process region and proximate to an edge ring that surrounds a wafer received within the process region. A foot extension has an inner end that joins to the lower end of the tubular extension and extends outwardly from the process region to the outer end. The foot extension provides an annular surface that is configured to form a gap with a top surface of the edge ring.

Abstract: Apparatuses and methods are provided. Some methods may include providing a substrate to a processing chamber, the substrate having a first material adjacent to and covering a surface of a second material, modifying a layer of the first material by flowing a first process gas onto the substrate and thereby creating a modified layer of the first material, removing the modified layer of the first material by flowing a second process gas onto the substrate, and converting, when the surface of the second material is uncovered via removal of the modified layer, the surface to a converted layer of the second material by flowing a third process gas onto the substrate, in which the first and second process gases are less reactive with the converted layer than with the first material and the second material.

Abstract: Methods and apparatuses for etching materials using a boron trichloride during atomic layer etching are provided. The method comprises providing a wafer to a processing chamber, the wafer having an oxygen-containing material, exposing the oxygen-containing material to a halogen-containing gas to form a modified oxygen-containing layer on a surface of the wafer, and exposing the modified oxygen-containing layer to the boron trichloride to remove the modified layer from the surface of the wafer.

Abstract: According to the invention, there is provided a solid pharmaceutical composition formulation for nasal delivery of an opioid antagonist, comprising a pharmacologically-effective amount of an opioid antagonist and a pharmaceutically-acceptable carrier. The compositions are preferably in the form of a powder produced by spray-drying, which are subsequently loaded into single use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include disaccharides (e.g. lactose or trehalose) and dextrins (e.g. cyclodextrins or maltodextrins), preferably spray-dried together in combination. Compositions may further comprise an alkyl saccharide, preferably a sucrose ester, such as sucrose monolaurate. The compositions and applicators may be employed in the treatment of opioid overdose in subjects.

Abstract: A plug connector housing for a plug connector, having a main body and a latching installation. The latching installation has a first connection portion integrally connecting the latching mechanism to the main body. A void extends along a longitudinal axis on the main body and is at least in portions formed between the latching installation and the main body. The plug connector housing furthermore has first and second protective elements which extend in each case integrally from the main body. The latching installation is disposed between the protective elements, wherein each of the protective elements in at least one covered region covers the void in a transverse direction. Each of the protective elements moreover configures at least one access region in which the void is accessible along the transverse direction. Each of the covered regions faces a respective access region of the respective other protective element along the transverse direction.

Abstract: The disclosure relates to a rotary atomizer for applying a spray jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that the construction dimensions of the rotary atomizer are coordinated in such a way that the air pressure at the outlet opening of the paint nozzle during operation is lower than the air pressure in the nozzle chamber of the bell cup and in the external rinsing channels in order to prevent a backflow of the coating agent from the outlet opening of the paint nozzle backwards in the direction of the nozzle chamber due to the pressure difference.

Abstract: An electrical contact element (3) is formed from a stamped and bent part and/or from a deep-drawn metal component (1). The electrical contact element (3) has a contact area (6) having an end-face contact surface (7) designed for electrical and mechanical contacting with an electrical mating contact element. The electrical contact element (3) also has a support area (8), which is arranged on a side of the contact area (6) facing away from the end-face contact surface (7) and is designed so as to mechanically support the contact area (6). It is provided that the contact area (6) is integrally connected to the support area (8) via a primary connecting section (9).

Abstract: Techniques for generating unregistered internet domain names using machine learning (e.g., neural networks) are presented. The techniques can include identifying, using an electronic processor, a subset of registered domain names having at least one specified characteristic, vectorizing, using an electronic processor, a training subset of domain names in the subset of registered domain names to obtain a set of vectors, training, using an electronic processor, a machine learning algorithm with the set of vectors to produce a trained machine learning model, generating, using an electronic processor, at least one output domain name by the trained machine learning model, and outputting the at least one output domain name.

Abstract: The disclosure relates to a bell cup for a rotary atomizer for painting components, having the following features: a hub for rotatably mounting the bell cup on the rotary atomizer, so that the bell cup is rotatable about an axis of rotation, an annular circumferential spraying edge for spraying the paint in the form of a spray jet, and a circumferential outer lateral surface which widens along the axis of rotation in the distal direction towards the spraying edge, The disclosure provides that the outer lateral surface of the bell cup is divided into different sections, which are angled differently. Furthermore, the disclosure comprises a rotary atomizer with such a bell cup, a painting installation and a corresponding painting method.

Abstract: There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of buprenorphine, or a pharmaceutically-acceptable salt thereof, in associative admixture with particles comprising a weak acid, or particles comprising weakly-acidic buffer forming materials. The composition may further comprise a disintegrant and/or particles of a pharmacologically-effective amount of naloxone, or a pharmaceutically-acceptable salt thereof. The compositions are useful in the treatment of opioid dependency/addiction and/or pain.

Abstract: The disclosure relates to a rotary atomizer for applying a spray jet of a coating agent (e.g. paint) to a component (e.g. motor vehicle body component). The disclosure provides that the construction dimensions of the rotary atomizer are coordinated in such a way that the air pressure at the outlet opening of the paint nozzle during operation is lower than the air pressure in the nozzle chamber of the bell cup and in the external rinsing channels in order to prevent a backflow of the coating agent from the outlet opening of the paint nozzle backwards in the direction of the nozzle chamber due to the pressure difference.

Abstract: A layer of a chalcogenide material can be etched by providing a wafer having a layer of the chalcogenide material to a processing chamber, heating the wafer to a first temperature, modifying a surface of the layer of chalcogenide material by flowing a first chemical species comprising a fluoride or a chloride onto the wafer to create a modified layer of chalcogenide material while the wafer is at the first temperature, and removing the modified layer of chalcogenide material, without using a plasma, by flowing a second chemical species comprising a compound with a center atom that is aluminum, boron, silicon, or germanium, and with at least one chlorine, onto the wafer.

Abstract: A method for controlling a servomotor with a converter includes monitoring a circuit of a direct-voltage DC link that is connected to an input circuit for flow of an electric current; switching off a first switching device to end the supply of the direct-voltage DC link from an electrical grid if a stop signal occurs; braking the servomotor by control of power semiconductor switches of an inverter circuit in a regenerative braking operation, to reduce the rotation speed of the servomotor, if the monitoring detects that an electric current is not flowing after the first switching device has been switched off; and switching off a second switching device to prevent feeding electrical energy from the direct-voltage DC link into the servomotor if the monitoring detects a flow of electric current after the first switching device has been switched off.

Abstract: A packaging laminate includes a carrier layer and a barrier film, wherein the carrier layer consists of paper with a grammage of 40 to 120 g/m2, wherein the barrier film is connected with the carrier layer via a connecting layer, wherein a plastics film stretched in at least one stretching direction is provided as the barrier film, wherein the barrier film has a layer thickness of 1 to 10 ?m, preferably less than 5 ?m and very preferably less than 3 ?m, and wherein the elongation at break of the barrier film in the at least one stretching direction is less than or equal to 180%, preferably less than or equal to 130%.

Abstract: According to the invention, there is provided a solid pharmaceutical composition formulation for nasal delivery of an opioid antagonist, comprising a pharmacologically-effective amount of an opioid antagonist and a pharmaceutically-acceptable carrier. The compositions are preferably in the form of a powder produced by spray-drying, which are subsequently loaded into single use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include disaccharides (e.g. lactose or trehalose) and dextrins (e.g. cyclodextrins or maltodextrins), preferably spray-dried together in combination. Compositions may further comprise an alkyl saccharide, preferably a sucrose ester, such as sucrose monolaurate. The compositions and applicators may be employed in the treatment of opioid overdose in subjects.

Abstract: Filter media for a drum filter that includes a plurality of annular frame members, each annular frame member having a circumference is disclosed. The filter media includes a filter sheet with first and second engagement strips having a cord portion and an attachment tab portion connected to the filter sheet. The first and second engagement strips engage with first and second connecting strips located on the annular frame members. Each connecting strip has a receiving portion that receives the cord portion of the associated engagement strip. Each connecting strip also has a body portion configured to engage a drum filter frame. An engagement mechanism configured to attach a filter sheet to a drum filter frame is also disclosed. A system for attaching a filter media to a cylindrical drum filter is also disclosed.

Abstract: According to the invention, there is provided a solid pharmaceutical composition formulation for nasal delivery of an opioid antagonist, comprising a pharmacologically-effective amount of an opioid antagonist and a pharmaceutically-acceptable carrier. The compositions are preferably in the form of a powder produced by spray-drying, which are subsequently loaded into single use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include disaccharides (e.g. lactose or trehalose) and dextrins (e.g. cyclodextrins or maltodextrins), preferably spray-dried together in combination. Compositions may further comprise an alkyl saccharide, preferably a sucrose ester, such as sucrose monolaurate. The compositions and applicators may be employed in the treatment of opioid overdose in subjects.

Abstract: According to the invention, there is provided a pharmaceutically-acceptable composition which is preferably in the form of a spray-dried powder comprising a mixture of: (a) a pharmacologically-effective dosage amount of at least one pharmaceutically-active compound; and (b) a pharmaceutically-acceptable carrier material, which carrier material comprises a combination of a disaccharide and a polymeric material. Compositions are suitable for, for example, transmucosal drug delivery, including sublingual and nasal delivery. In the case of nasal delivery, said compositions may be loaded into single- or multiple-use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include lactose or trehalose and dextrins (e.g. cyclodextrins or maltodextrins), which may be spray-dried together in combination. Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate.

Abstract: The invention relates to a motor-driven covering device (2) for covering and exposing a charging connection (8) arranged on the body (4) of an electric vehicle (6) with respect to a vehicle exterior (16), comprising a cover flap (10) for covering the charging connection (8) in a closed state (I), a motor (12) operatively connected to the cover flap (10) for driving an opening movement and a closing movement of the cover flap (10), a power transmission means/device (14) for transmitting a motor power of the motor (12) for carrying out the opening movement and the closing movement of the cover flap (10), guide means/element (18) for guiding the cover flap (10) along a movement path during the opening movement and the closing movement of the cover flap (10), the motor-driven covering device (2) being configured in such a manner that the cover flap (10) can be moved along the body (4) of the electric vehicle (6) in a motor-driven manner during the opening and closing movement, wherein the body (4) at least partia