Abstract: According to the invention, there is provided a solid pharmaceutical composition formulation for nasal delivery of an opioid antagonist, comprising a pharmacologically-effective amount of an opioid antagonist and a pharmaceutically-acceptable carrier. The compositions are preferably in the form of a powder produced by spray-drying, which are subsequently loaded into single use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include disaccharides (e.g. lactose or trehalose) and dextrins (e.g. cyclodextrins or maltodextrins), preferably spray-dried together in combination. Compositions may further comprise an alkyl saccharide, preferably a sucrose ester, such as sucrose monolaurate. The compositions and applicators may be employed in the treatment of opioid overdose in subjects.

Abstract: According to the invention, there is provided a pharmaceutically-acceptable composition which is preferably in the form of a spray-dried powder comprising a mixture of: (a) a pharmacologically-effective dosage amount of at least one pharmaceutically-active compound; and (b) a pharmaceutically-acceptable carrier material, which carrier material comprises a combination of a disaccharide and a polymeric material. Compositions are suitable for, for example, transmucosal drug delivery, including sublingual and nasal delivery. In the case of nasal delivery, said compositions may be loaded into single- or multiple-use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include lactose or trehalose and dextrins (e.g. cyclodextrins or maltodextrins), which may be spray-dried together in combination. Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate.

Abstract: The invention relates to a motor-driven covering device (2) for covering and exposing a charging connection (8) arranged on the body (4) of an electric vehicle (6) with respect to a vehicle exterior (16), comprising a cover flap (10) for covering the charging connection (8) in a closed state (I), a motor (12) operatively connected to the cover flap (10) for driving an opening movement and a closing movement of the cover flap (10), a power transmission means/device (14) for transmitting a motor power of the motor (12) for carrying out the opening movement and the closing movement of the cover flap (10), guide means/element (18) for guiding the cover flap (10) along a movement path during the opening movement and the closing movement of the cover flap (10), the motor-driven covering device (2) being configured in such a manner that the cover flap (10) can be moved along the body (4) of the electric vehicle (6) in a motor-driven manner during the opening and closing movement, wherein the body (4) at least partia

Abstract: A support frame for dust collection system including a drum filter and a filter cleaning system is disclosed where the frame includes a plurality of octagonal supports spaced apart from each other in an axial direction defining an octagon-shaped peripheral profile. A plurality of axial members extend between adjacent octagonal supports, and end covers are secured to the frame members with each cover including a first inlet opening and a second inlet opening. The support frame may be used in a modular dust collection with a plurality of modular segments of filter media segments secured to the frame and a filter cleaner segments corresponding to the filter media segments.

Abstract: A method for operating a hydraulic actuator for a prime mover or a drive device of a vehicle includes determining that the hydraulic actuator is to be actuated via an actuating system and detecting an operating variable influenced by a filling state of the hydraulic actuator indicative of pressure conditions in the hydraulic actuator, with the operating variable being separate from actuator operating variables of the hydraulic actuator and the actuating system. The method further includes pressurizing the actuator during a fast fill phase to one or more pressures over a fast fill time period in response to determining that the hydraulic actuator is to be actuated. The fast fill time period and the one or more pressures are adjusted as a function of the operating variable under certain operating conditions. Additionally, the method includes pressurizing the actuator during a pressure build-up phase after the fast fill phase.

Abstract: Apparatuses and methods are provided. Some methods may include providing a substrate to a processing chamber, the substrate having a first material adjacent to and covering a surface of a second material, modifying a layer of the first material by flowing a first process gas onto the substrate and thereby creating a modified layer of the first material, removing the modified layer of the first material by flowing a second process gas onto the substrate, and converting, when the surface of the second material is uncovered via removal of the modified layer, the surface to a converted layer of the second material by flowing a third process gas onto the substrate, in which the first and second process gases are less reactive with the converted layer than with the first material and the second material.

Abstract: Disclosed are apparatuses and methods for performing atomic layer etching. A method may include modifying one or more surface layers of material on the substrate and exposing the one or more modified surface layers on the substrate to an electron source thereby removing, without using a plasma, the one or more modified surface layers on the substrate. An apparatus may include a processing chamber, a process gas unit, an electron source, and a controller with instructions configured to cause the process gas unit to flow a first process gas to a substrate in a chamber interior, the first process gas is configured to modify one or more layers of material on the substrate, and to cause the electron source to generate electrons and expose the one or more modified surface layers on the substrate to the electrons, the one or more modified surface layers being removed, without using a plasma.

Abstract: An actuating clip (1) for a connector (10), having a cable receptacle (2) for receiving at least one cable; connecting means in order to connect the actuating clip to the connector in such a manner that the actuating clip adjoins the connector at a cable-side end of the connector; surfaces for actuating the connector (10), which are configured to ensure guiding of the connector (10) when the latter is connected to an actuating clip by the surfaces of the actuating clip (1) being able to be gripped by a human hand and/or by a gripping tool, wherein the surfaces of the actuating clip (1) are specifically designed to be gripped by a hand and/or by a gripping tool.

Abstract: A lixiviant medium for extracting gold from a gold-containing solid material contains a polyether-modified siloxane and a non-ionic surfactant. The lixiviant medium can be used in a method of extracting gold from a gold-containing solid material. The lixiviant medium can be prepared from a composition containing a non-ionic surfactant and a polyether-modified siloxane. A method of preparing the lixiviant medium involves mixing the composition with an alkali metal cyanide, a pH regulator suitable for setting a pH of the composition to a value of 9 or higher, and water.

Abstract: Indium gallium zinc oxide can be etched by providing a wafer having a layer of indium gallium zinc oxide to a processing chamber, heating the wafer to a first temperature, flowing a first chemical species comprising a fluoride to create a layer of indium gallium zinc oxyfluoride, and removing the layer of indium gallium zinc oxyfluoride by flowing a second chemical species comprising an alkyl aluminum halide, an aluminum alkalide, an organoaluminium compound, a diketone, silicon halide, silane, halogenated silane, or alkyl silicon halide.

Abstract: Semiconductor processing methods and apparatuses are provided. Some methods include providing a substrate to a processing chamber, the substrate having a semiconductor portion and a dielectric portion, modifying the semiconductor portion of the substrate selective to the dielectric portion of the substrate by flowing a first process gas comprising a first halogen species onto the substrate and providing a first activation energy to cause the first halogen species to preferentially adsorb on the semiconductor portion relative to the dielectric portion to form a first halogenated semiconductor, and removing the first halogenated semiconductor by flowing a second process gas comprising a second halogen species onto the substrate and providing a second activation energy, without providing a plasma, to cause the second halogen species to react with the first halogenated semiconductor and cause the first halogenated semiconductor to desorb from the substrate.

Abstract: According to the invention, there is provided a pharmaceutically-acceptable composition which is preferably in the form of a spray-dried powder comprising a mixture of: (a) a pharmacologically-effective dosage amount of at least one pharmaceutically-active compound; and (b) a pharmaceutically-acceptable carrier material, which carrier material comprises a combination of a disaccharide and a polymeric material. Compositions are suitable for, for example, transmucosal drug delivery, including sublingual and nasal delivery. In the case of nasal delivery, said compositions may be loaded into single- or multiple-use nasal applicators. Preferred pharmaceutically-acceptable carriers in this regard include lactose or trehalose and dextrins (e.g. cyclodextrins or maltodextrins), which may be spray-dried together in combination. Compositions may further comprise one or more alkyl saccharides. Preferred alkyl saccharides include sucrose esters, such as sucrose monolaurate.

Abstract: The disclosure relates to a method for programming a program-controlled coating installation with a coating robot and an application device for coating components, in particular for programming a painting installation with a painting robot for painting motor vehicle body components, with the following steps (S1-S3): a) Presetting or determining geometry data of the component to be coated (S1), b) presetting of robot path data of the robot path to be traversed (S2), and c) determination of suitable spray pattern data (S3) which represent a layer thickness profile and are determined by a simulation which takes into account the robot path data and the geometry data of the component to be coated. Furthermore, the disclosure comprises an appropriately adapted coating installation.

Abstract: A hitherto unknown crystalline form of (?)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride, pharmaceutical compositions containing the new crystalline form, methods of producing the new crystalline form, and a related method of use including treatment of, e.g., pain and/or urinary incontinence.

Abstract: Disclosed are apparatuses and methods for performing atomic layer etching. A method may include modifying one or more surface layers of material on the substrate and exposing the one or more modified surface layers on the substrate to an electron source thereby removing, without using a plasma, the one or more modified surface layers on the substrate. An apparatus may include a processing chamber, a process gas unit, an electron source, and a controller with instructions configured to cause the process gas unit to flow a first process gas to a substrate in a chamber interior, the first process gas is configured to modify one or more layers of material on the substrate, and to cause the electron source to generate electrons and expose the one or more modified surface layers on the substrate to the electrons, the one or more modified surface layers being removed, without using a plasma.

Abstract: A plug connector housing for a plug connector, having a main body and a latching installation. The latching installation has a first connection portion integrally connecting the latching mechanism to the main body. A void extends along a longitudinal axis on the main body and is at least in portions formed between the latching installation and the main body. The plug connector housing furthermore has first and second protective elements which extend in each case integrally from the main body. The latching installation is disposed between the protective elements, wherein each of the protective elements in at least one covered region covers the void in a transverse direction. Each of the protective elements moreover configures at least one access region in which the void is accessible along the transverse direction. Each of the covered regions faces a respective access region of the respective other protective element along the transverse direction.

Abstract: A cover layer of a fleece material for an innerspring unit comprising a plurality of pocketed springs is manufactured by supplying at least two longitudinal fleece webs, which extend substantially parallel in a longitudinal direction and are spaced from one another, and repeatedly attaching a transverse fleece web, which extends between the longitudinal fleece webs in a direction substantially perpendicular to the longitudinal direction, to the longitudinal fleece webs. The transverse fleece web segments are attached to the longitudinal fleece webs such that they form together with the longitudinal fleece webs a frame-like structure serving as the cover layer.

Abstract: Molybdenum is etched in a highly controllable manner by performing one or more etch cycles, where each cycle involves exposing the substrate having a molybdenum layer to an oxygen-containing reactant to form molybdenum oxide followed by treatment with boron trichloride to convert molybdenum oxide to a volatile molybdenum oxychloride with subsequent treatment of the substrate with a fluorine-containing reactant to remove boron oxide that has formed in a previous reaction, from the surface of the substrate. In some embodiments the method is performed in an absence of plasma and results in a substantially isotropic etching. The method can be used in a variety of applications in semiconductor processing, such as in wordline isolation in 3D NAND fabrication.

Abstract: A method for controlling a servomotor with a converter includes monitoring a circuit of a direct-voltage DC link that is connected to an input circuit for flow of an electric current; switching off a first switching device to end the supply of the direct-voltage DC link from an electrical grid if a stop signal occurs; braking the servomotor by control of power semiconductor switches of an inverter circuit in a regenerative braking operation, to reduce the rotation speed of the servomotor, if the monitoring detects that an electric current is not flowing after the first switching device has been switched off; and switching off a second switching device to prevent feeding electrical energy from the direct-voltage DC link into the servomotor if the monitoring detects a flow of electric current after the first switching device has been switched off.

Abstract: A system for computed tomography inspection can include a stage, a stationary radiation source, a stationary radiation detector, and a controller. The stage can secure a target thereon and rotate about a rotation axis. The radiation source can emit a beam of penetrating radiation from a focal point that is directed upon a portion of the target. The radiation detector can include a sensing face configured to acquire measurements of radiation beam intensity incident thereon as a function of position. The controller can command the stage to translate from a first position to a second position in a direction transverse to a central axis of the radiation beam. A magnification of the target at the first and second positions can be approximately equal. The stage does not translate transverse to the central axis of the radiation beam during measurement of the radiation beam intensity by the detector.