Patents by Inventor Andreas PHILIPP

Andreas PHILIPP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11840515
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: December 12, 2023
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Publication number: 20220024871
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Application
    Filed: March 16, 2021
    Publication date: January 27, 2022
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10981870
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: April 20, 2021
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10981871
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: April 20, 2021
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10923251
    Abstract: An arrangement has a coaxial resistor. The coaxial resistor is to be placed on an electrically conductive housing, and sensor lines of the coaxial resistor are to be guided through an interior of the coaxial resistor into the interior of the electrically conductive housing and to be connected to an electrical interface in the electrically conductive housing.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: February 16, 2021
    Assignee: Siemens Aktiengesellschaft
    Inventors: Wilhelm Delchmann, Michael Hofstetter, Andreas Philipp, Michael Zorawik
  • Publication number: 20200300283
    Abstract: The present invention relates to a connecting element for non-detachably connecting at least two components by means of friction welding when the connecting element is rotated about a longitudinal axis of the connecting element. The connecting element includes a stem formed along the longitudinal axis with a stem face at a free end of the stem for penetrating at least one component, and a head connected to the stem for transmitting a torque about the longitudinal axis from a turning tool to the stem. The stem face has a stem end face which has a convex envelope with a blunt shape.
    Type: Application
    Filed: November 8, 2018
    Publication date: September 24, 2020
    Applicant: ARNOLD UMFORMTECHNIK GmbH & Co. KG
    Inventors: Dominik FRÖHLICH, Georg VOGEL, Andreas PHILIPP, Patrick ROMINGER, Klaus TRUETSCH
  • Publication number: 20200181087
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Application
    Filed: February 10, 2020
    Publication date: June 11, 2020
    Applicant: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Publication number: 20200165202
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N,-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —OR, or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-4 alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N- methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobemzyl)-N-(1-methylpiperidin-4-yl)-N?,-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 28, 2020
    Applicant: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10597363
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: March 24, 2020
    Assignee: ACADIA Pharmaceuticals Inc.
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10530644
    Abstract: A method for establishing a communication connection between a first network entity and a second network entity via at least two different network flows includes: transmitting a first request, by the first network entity, directed to the second network entity via a first network flow; transmitting at least one second request, by the first network entity, directed to the second network entity via at least one second network flow, wherein the at least one second request is transmitted by the first network entity before the first network entity receives a reply to the first request from the second network entity; and establishing the communication connection between the first network entity and the second network entity based on at least one of the first request or the at least one second request.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: January 7, 2020
    Assignee: DEUTSCHE TELEKOM AG
    Inventors: Markus Amend, Eckard Bogenfeld, Andreas Philipp Matz
  • Patent number: 10468884
    Abstract: A device controls a load flow in an alternating-voltage network. The device is distinguished by a module series circuit of two-pole switching modules that can be inserted in series into a phase line of the alternating-voltage network. Each switching module has an energy store and controllable power semiconductors that can be switched on an off and each switching module can be controlled in such a way that a switching-module voltage can be produced at the poles thereof, which switching-module voltage corresponds to a positive or negative energy-store voltage or a voltage having the value of zero. A control apparatus for controlling the switching modules is provided, which control apparatus is configured to control the switching modules in such a way that a periodic longitudinal voltage can be produced at the module series circuit. A method for controlling a load flow in an alternating-voltage network is performed by the device.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: November 5, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Friedemann Augsburger, Dominik Ergin, Hans-Joachim Knaak, Andreas Philipp, Jochen Schaefer
  • Publication number: 20190180893
    Abstract: An arrangement has a coaxial resistor. The coaxial resistor is to be placed on an electrically conductive housing, and sensor lines of the coaxial resistor are to be guided through an interior of the coaxial resistor into the interior of the electrically conductive housing and to be connected to an electrical interface in the electrically conductive housing.
    Type: Application
    Filed: December 12, 2018
    Publication date: June 13, 2019
    Inventors: WILHELM DELCHMANN, MICHAEL HOFSTETTER, ANDREAS PHILIPP, MICHAEL ZORAWIK
  • Patent number: 10243357
    Abstract: An apparatus switches a direct current in a high-voltage line. The apparatus contains a multiplicity of switching units, which are arranged so as to form a series circuit in the high-voltage line. Each switching unit in this case contains a switching element and a surge arrester arranged in a parallel circuit with the switching element, the threshold voltage of the surge arrester being higher than a rated voltage of the switching element. A sum of the rated voltages of the switching elements corresponds at least to an operating voltage of the high-voltage line. The switching elements are mechanical switches, and each mechanical switch contains a contact arrangement having two disconnectable contact pieces and is configured to build up an arcing voltage on disconnection of the contact pieces with a magnitude which is higher than the rated voltage of the mechanical switch.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: March 26, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventors: Hans-Guenter Eckel, Dominik Ergin, Herbert Gambach, Hans-Joachim Knaak, Andreas Philipp, Hubert Schierling
  • Publication number: 20190047955
    Abstract: Disclosed herein are methods for obtaining N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide (pimavanserin) comprising the step of contacting an intermediate according to Formula (A) or a salt thereof, with an intermediate Formula B, or a salt thereof, to produce pimavanserin or a salt thereof wherein Y is —ORi or —NR2aR2b; R3 is hydrogen or substituted or unsubstituted heteroalicyclyl, R4 is substituted or unsubstituted aralkyl; X is —OR22 or —NR23R24; (wherein R22 is hydrogen or substituted or unsubstituted C1-6alkyl and one of R23 and R24 is hydrogen and the other is hydrogen or N-methylpiperidin-4-yl); and R21 is —OCH2CH(CH3)2 or F; Also disclosed herein is the tartrate salt of N-(4-fluoroben-zyl)-N-(1-methylpiperidin-4-yl)-N?-(4-(2-methylpropyloxy)phenylmethyl) carbamide and methods for obtaining the salt.
    Type: Application
    Filed: July 19, 2016
    Publication date: February 14, 2019
    Inventors: Marlon Carlos, Sagun Tandel, Roger Olsson, Mikael Hillgren, Matthew J. Fleming, Andreas Philipp Boudier, Beat T. Weber
  • Patent number: 10163546
    Abstract: A field control device for a high-voltage system includes a shielding element for field control, which can be connected to an electrical conductor of the high-voltage system in an electrically conductive manner and, when connected to the conductor, at least partly delimits a weak-electric-field spatial region. A cooling body, which can be connected to the electrical conductor in a thermally conductive manner and which is disposed within the weak-field spatial region, has an outer surface area which is greater than an outer surface area of the shielding element. A high-voltage system having the field control device is also provided.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: December 25, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Michael Hofstetter, Jochen Schaefer, Andreas Philipp
  • Publication number: 20180358808
    Abstract: A device controls a load flow in an alternating-voltage network. The device is distinguished by a module series circuit of two-pole switching modules that can be inserted in series into a phase line of the alternating-voltage network. Each switching module has an energy store and controllable power semiconductors that can be switched on an off and each switching module can be controlled in such a way that a switching-module voltage can be produced at the poles thereof, which switching-module voltage corresponds to a positive or negative energy-store voltage or a voltage having the value of zero. A control apparatus for controlling the switching modules is provided, which control apparatus is configured to control the switching modules in such a way that a periodic longitudinal voltage can be produced at the module series circuit. A method for controlling a load flow in an alternating-voltage network is performed by the device.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 13, 2018
    Inventors: FRIEDEMANN AUGSBURGER, DOMINIK ERGIN, HANS-JOACHIM KNAAK, ANDREAS PHILIPP, JOCHEN SCHAEFER
  • Publication number: 20180268963
    Abstract: A field control device for a high-voltage system includes a shielding element for field control, which can be connected to an electrical conductor of the high-voltage system in an electrically conductive manner and, when connected to the conductor, at least partly delimits a weak-electric-field spatial region. A cooling body, which can be connected to the electrical conductor in a thermally conductive manner and which is disposed within the weak-field spatial region, has an outer surface area which is greater than an outer surface area of the shielding element. A high-voltage system having the field control device is also provided.
    Type: Application
    Filed: November 1, 2016
    Publication date: September 20, 2018
    Inventors: MICHAEL HOFSTETTER, JOCHEN SCHAEFER, ANDREAS PHILIPP
  • Patent number: 10032589
    Abstract: An actuating device for a vacuum switching tube has a connecting element which can be connected to an electric contact of the vacuum switching tube, an electromagnetic actuating device for displacing the connecting element between a first and a second position, and a retaining yoke, relative to which the connecting element can be displaced and has a first magnetic element. The first magnetic element generates a first and a second magnetic circuit in the retaining yoke. The actuating device further has a ferromagnetic retaining anchor, which is arranged on the connecting element. The retaining anchor is located in the first position of the connecting element in the first magnetic circuit and in the second position of the connecting element in the second magnetic circuit. The connecting element is held in the first and in the second position by a respective magnetic force between the retaining yoke and the retaining anchor.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: July 24, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Georg Bachmaier, Dominik Ergin, Andreas Goedecke, Sylvio Kosse, Andreas Philipp
  • Publication number: 20180034691
    Abstract: A method for establishing a communication connection between a first network entity and a second network entity via at least two different network flows includes: transmitting a first request, by the first network entity, directed to the second network entity via a first network flow; transmitting at least one second request, by the first network entity, directed to the second network entity via at least one second network flow, wherein the at least one second request is transmitted by the first network entity before the first network entity receives a reply to the first request from the second network entity; and establishing the communication connection between the first network entity and the second network entity based on at least one of the first request or the at least one second request.
    Type: Application
    Filed: July 27, 2017
    Publication date: February 1, 2018
    Inventors: Markus AMEND, Eckard BOGENFELD, Andreas Philipp MATZ
  • Patent number: 9806532
    Abstract: A method for switching an operating current in a meshed DC voltage network enables operating currents in a DC voltage network to be switched economically in both directions. At least one converter connected to the DC voltage network is controlled in such a way that a zero current is generated in a switching branch having a mechanical switch and the mechanical switch is actuated in accordance with the generated zero current.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: October 31, 2017
    Assignee: Siemens Aktiengesellschaft
    Inventors: Dominik Ergin, Hans-Joachim Knaak, Andreas Philipp