Abstract: A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includes includes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.

Abstract: A filter element has a pleated filter mat (3). The terminal axial ends (7, 8) of the mat are connected to end caps (9, 11). The mat has a main structural layer (15) having filtering properties and a first additional structural layer and a second additional structural layer (17,19). The surface area of each of the additional structural layers (17, 19) is smaller than the surface area of the main structural layer (15). The axial ends (12, 14) of one additional structural layer (17) is located at an axial distance from the axial ends (16, 18) of the other additional structural layer (19) on the filter mat (3).

Abstract: A schematic block diagram of an audio encoder for encoding a multichannel audio signal is shown. The audio encoder includes a linear prediction domain encoder, a frequency domain encoder, and a controller for switching between the linear prediction domain encoder and the frequency domain encoder. The controller is configured such that a portion of the multichannel signal is represented either by an encoded frame of the linear prediction domain encoder or by an encoded frame of the frequency domain encoder. The linear prediction domain encoder includes a downmixer for downmixing the multichannel signal to obtain a downmixed signal. The linear prediction domain encoder further includes a linear prediction domain core encoder for encoding the downmix signal and furthermore, the linear prediction domain encoder includes a first joint multichannel encoder for generating first multichannel information from the multichannel signal.

Abstract: An apparatus for generating an enhanced signal from an input signal, wherein the enhanced signal has spectral values for an enhancement spectral region, the spectral values for the enhancement spectral regions not being contained in the input signal, includes a mapper for mapping a source spectral region of the input signal to a target region in the enhancement spectral region, the source spectral region including a noise-filling region; and a noise filler configured for generating first noise values for the noise-filling region in the source spectral region of the input signal and for generating second noise values for a noise region in the target region, wherein the second noise values are decorrelated from the first noise values or for generating second noise values for a noise region in the target region, wherein the second noise values are decorrelated from first noise values in the source region.

Abstract: A new, stable trimeric TNF? structure is disclosed with distorted symmetry which can bind to the TNFR1 receptor to attenuate signalling therefrom, which can be used in the treatment and/or prevention of diseases associated with the soluble TNF?/TNFR1 interaction. Membrane-bound TNF? is not affected in its ability to signal through TNFR2, and thus the new structure of TNF? may be used in therapies which do not significantly raise the risk of infection or malignancy.

Abstract: An Al—Mg-based or Al—Mg—Si-based or Al—Zn-based or Al—Si-based starting material in the form of a powder or wire for an additive manufacturing process, the use thereof, and an additive manufacturing process using this starting material are disclosed.

Abstract: A method for simple measurement of phase shift between a first clock signal and a second clock signal is described, each clock signal having a period T0. The method includes: feeding the first clock signal into a first input of a mixer; feeding the second clock signal into a second input of the mixer; feeding the output signal of the mixer into a low pass filter; and measuring the output signal of the low pass filter, with the aid of an output voltage that is normalized to operating voltage of the mixer. A circuit for implementing the method includes a mixer and a low pass filter. The mixer includes a first input for feeding in the first clock signal, and a second input for feeding in the second clock signal. The output of the mixer is connected to the input of the low pass filter.

Abstract: An input stage for an LVDS receiver circuit is provided, which includes at least one supply voltage connection as well as a first and a second stage input to be acted upon by a differential input signal pair. The input stage further includes a first and a second differential stage, the stage inputs being directly connected to one input each of the first differential stage and indirectly, via one level-shifting circuit each, to one input each of the second differential stage. According to the present invention, the first and the second differential stage are connected to the supply voltage connection via one transistor each of a third differential stage, the control input of one of these transistors being connected to a measuring path connecting the stage inputs to one another, with the control input of the other transistor being connected to an apparatus/device (arrangement) for providing a reference voltage.

Abstract: An input stage for an LVDS receiver circuit is provided, which includes at least one supply voltage connection as well as a first and a second stage input to be acted upon by a differential input signal pair. The input stage further includes a first and a second differential stage, the stage inputs being directly connected to one input each of the first differential stage and indirectly, via one level-shifting circuit each, to one input each of the second differential stage. According to the present invention, the first and the second differential stage are connected to the supply voltage connection via one transistor each of a third differential stage, the control input of one of these transistors being connected to a measuring path connecting the stage inputs to one another, with the control input of the other transistor being connected to an apparatus/device (arrangement) for providing a reference voltage.

Abstract: A detector circuit for galvanically isolated transmission of digital signals. The detector circuit includes two differential signal inputs, one input common-mode voltage connection, one alternating voltage coupling, and one differential stage. The detector circuit also includes one operating voltage connection, one operating ground connection, one signal output, one bias current connection, and one rectifier stage. The alternating current coupling includes two capacitors and two resistors. The differential stage includes a first n-channel transistor and a second n-channel transistor. The bias current connection is connected to the differential stage via a third n-channel transistor. The bias current connection is connected to the rectifier stage via a fourth n-channel transistor and a fifth n-channel transistor. The rectifier stage includes five p-channel transistors.

Abstract: A detector circuit for galvanically isolated transmission of digital signals. The detector circuit includes two differential signal inputs, one input common-mode voltage connection, one alternating voltage coupling, and one differential stage. The detector circuit also includes one operating voltage connection, one operating ground connection, one signal output, one bias current connection, and one rectifier stage. The alternating current coupling includes two capacitors and two resistors. The differential stage includes a first n-channel transistor and a second n-channel transistor. The bias current connection is connected to the differential stage via a third n-channel transistor. The bias current connection is connected to the rectifier stage via a fourth n-channel transistor and a fifth n-channel transistor. The rectifier stage includes five p-channel transistors.

Abstract: A new, stable trimeric TNF? structure is disclosed with distorted symmetry which can bind to the TNFR1 receptor to attenuate signalling therefrom, which can be used in the treatment and/or prevention of diseases associated with the soluble TNF?/TNFR1 interaction. Membrane-bound TNF? is not affected in its ability to signal through TNFR2, and thus the new structure of TNF? may be used in therapies which do not significantly raise the risk of infection or malignancy.

Abstract: A new, stable trimeric TNF? structure is disclosed with distorted symmetry which can bind to the TNFR1 receptor to attenuate signalling therefrom, which can be used in the treatment and/or prevention of diseases associated with the soluble TNF?/TNFR1 interaction. Membrane-bound TNF? is not affected in its ability to signal through TNFR2, and thus the new structure of TNF? may be used in therapies which do not significantly raise the risk of infection or malignancy.

Abstract: A formulation for the coating of substrates, the formulation including 5 to 70 wt % of hydroxy-functional fluoropolymers, 5 to 70 wt % of polyesters based on dicarboxylic or polycarboxylic acids or derivatives thereof and on aliphatic or cycloaliphatic diols or polyols, the polyester including at least one aliphatic or cycloaliphatic dicarboxylic acid or polycarboxylic acid or derivatives thereof, 2 to 25 wt % of crosslinkers, 0.01 to 2 wt % of crosslinking catalysts, up to 20 wt % of UV absorbers and up to 10 wt % of UV stabilizers.

Abstract: An Al—Mg-based or Al—Mg—Si-based or Al—Zn-based or Al—Si-based starting material in the form of a powder or wire for an additive manufacturing process, the use thereof, and an additive manufacturing process using this starting material are disclosed.

Abstract: A method for protecting personnel working in a wind turbine nacelle or hub includes monitoring a nacelle roof hatch and a hub access hatch, each hatch having a switch configured therewith. When at least one of the hatches is detected as opened, a control system detects if a rotor lock has been engaged. If the rotor lock has not been engaged, the control system triggers a rotor brake to stop rotor and drivetrain component rotational movement and actuates a first control lockout between the respective switch configured with the open hatch and the rotor brake. The control system also initiates a control lockout that prevents release of the rotor brake until the switch indicates that the open hatch has been closed and the first control lockout has been reset.

Abstract: A cylinder for a reciprocating piston system, with a cylinder running surface, which is finished by machining by means of a tool with a geometrically defined cutting edge, wherein the finished cylinder running surface has a multiplicity of pores and/or cavities and is formed from a grey cast iron material with a proportion of the surface area that is taken up by pores of 2 to 10% or is formed from a thermally sprayed layer of iron or a thermally sprayed layer of ceramic with a proportion of the surface area that is taken up by pores of 5 to 25%. A method is also provided for finishing a cylinder in which a cylinder running surface of the cylinder is finished by machining by a tool with a geometrically defined cutting edge such that after the finishing the cylinder surface has a multiplicity of pores and/or cavities.

Abstract: A method for protecting personnel working in a wind turbine nacelle or hub includes monitoring a nacelle roof hatch and a hub access hatch, each hatch having a switch configured therewith. When at least one of the hatches is detected as opened, a control system detects if a rotor lock has been engaged. If the rotor lock has not been engaged, the control system triggers a rotor brake to stop rotor and drivetrain component rotational movement and actuates a first control lockout between the respective switch configured with the open hatch and the rotor brake. The control system also initiates a control lockout that prevents release of the rotor brake until the switch indicates that the open hatch has been closed and the first control lockout has been reset.

Abstract: A new, stable trimeric TNF? structure is disclosed with distorted symmetry which can bind to the TNFR1 receptor to attenuate signalling therefrom, which can be used in the treatment and/or prevention of diseases associated with the soluble TNF?/TNFR1 interaction. Membrane-bound TNF? is not affected in its ability to signal through TNFR2, and thus the new structure of TNF? may be used in therapies which do not significantly raise the risk of infection or malignancy.

Abstract: A formulation for the coating of substrates, the formulation including 5 to 70 wt % of hydroxy-functional fluoropolymers, 5 to 70 wt % of polyesters based on dicarboxylic or polycarboxylic acids or derivatives thereof and on aliphatic or cycloaliphatic diols or polyols, the polyester including at least one aliphatic or cycloaliphatic dicarboxylic acid or polycarboxylic acid or derivatives thereof, 2 to 25 wt % of crosslinkers, 0.01 to 2 wt % of crosslinking catalysts, up to 20 wt % of UV absorbers and up to 10 wt % of UV stabilizers.