Abstract: The invention relates to a vibration dosimeter (2) and a method for determining the daily vibrational loading of persons who are exposed to mechanical oscillations at their place of work due to the operation of a work means and in particular of a manually operated electronic tool (4, 6). What is provided is that the dosimeter (2) comprises a determination device (12, 18) for determining the effective daily operating duration of the work means (4, 6), a computer device (22) for calculating a daily work time until a specified trigger value or exposition limit value of the vibrational loading is reached from a work-means-typical vibration value and the trigger value or exposition limit value, and a comparison device (24) for comparing the determined effective daily operating duration of the work means with the calculated daily work time until the specified trigger value is reached.

Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bmf”, and to genetic sequences encoding same and to regulatory sequences such as a promoter sequence directing expression of Bmf. Bmf comprises a BH3 domain which facilitates interaction to pro-survival Bcl-2 family members thereby triggering apoptosis. Bmf is regarded, therefore, as a BH3-only molecule. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.

Abstract: The invention relates to a tool receptacle (1), in particular for a hammer drill and/or rotary hammer, comprising a receptacle body (2) which has an insertion opening (3) for accommodating a tool shank (4), an axially displaceable locking control element (41) for axially locking the tool shank (4) in the insertion opening (3), and a rotatably mounted locking control body (41) for rotationally locking the receptacle body (2). Provision is made for the locking control element and the locking control body to be designed as a common component (41).

Abstract: A vibration dosimeter (2) for determining the vibrational loading of people comprises a determination device (6) for determining the operating period duration, a calculation device (6) for calculating the permitted work time as a function of a tool-specific characteristic vibration value, a comparison device (6) for comparing the effective operating period duration with the permitted work time, and an interface (3) for reading in the characteristic vibration value from the tool (1).

Abstract: The invention relates to a machine tool comprising an electric motor (2) which serves to drive a tool and which has an adjustable, electric brush arrangement (3), and comprising a mode selector switch (6) having various switch positions. Provision is made for an adjusting device (8) to displace the brush arrangement (3) as a function of the switch position of the mode selector switch (6). Furthermore, the invention relates to a corresponding method.

Abstract: A handle for an electric hand tool, which in use, is detachably connected to the hand tool as an auxiliary handle (2), includes at least one detection device (6), which communicates with at least one regulating and/or control element in the electric hand tool through a contactless signal transmission device.

Abstract: A hand-held power tool has a main element; a main handle fastened to the main element, the main handle being supported such that the main handle is movable relative to the main element, the main element including a tool fitting that defines a tool axis and the center of gravity that defines a normal direction oriented perpendicular to the tool axis and pointing toward the center of gravity, the main element being moved out of a stationary position toward the main handle so that a portion of at least 10% by weight of the main element is guided with a movement component in the normal direction along a trajectory.

Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bim”, and to genetic sequences encoding same. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.

Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bmf”, and to genetic sequences encoding same and to regulatory sequences such as a promoter sequence directing expression of Bmf. Bmf comprises a BH3 domain which facilitates interaction to pro-survival Bcl-2 family members thereby triggering apoptosis. Bmf is regarded, therefore, as a BH3-only molecule. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.

Abstract: The present invention concerns a device (10) for the manufacture of compressed particle beds having a container (22) for receiving particles respectively materials in particle form, a guiding device (14) for the support and guidance of the container (22) and a compression equipment (22), whereby the compression equipment (20) is in effective connection with the container (22).

Abstract: The invention relates to a vibration dosimeter (2) and a method for determining the daily vibrational loading of persons who are exposed to mechanical oscillations at their place of work due to the operation of a work means and in particular of a manually operated electronic tool (4, 6). What is provided is that the dosimeter (2) comprises a determination device (12, 18) for determining the effective daily operating duration of the work means (4, 6), a computer device (22) for calculating a daily work time until a specified trigger value or exposition limit value of the vibrational loading is reached from a work-means-typical vibration value and the trigger value or exposition limit value, and a comparison device (24) for comparing the determined effective daily operating duration of the work means with the calculated daily work time until the specified trigger value is reached.

Abstract: In a method of processing a contact pad, a passivation layer stack including at least one passivation layer is formed on at least an upper surface of a contact pad region. A first portion of the passivation layer stack is removed from above the contact pad region, wherein a second portion of the passivation layer remains on the contact pad region and covers the contact pad region. An adhesion layer is formed on the passivation layer stack. The adhesion layer is patterned, wherein the adhesion layer is removed from above the contact pad region. Furthermore, the second portion of the passivation layer stack is removed.

Abstract: A chuck is described, in particular for a hammer drill or chisel hammer, having a chuck body having an insertion opening for holding a tool shank, and a locking element for axially locking the tool shank in the insertion opening, the locking element being movable between a locked position and an unlocked position, and having an arresting pin, mounted in the locking element and radially displaceable between an arresting position and a release position, which axially arrests the locking element in its arresting position and axially releases it in its release position.

Abstract: A hand-held power tool, in particular a rotary hammer, is indicated that includes a machine housing (10) with a tool fitting (12) integrated therein, the tool fitting (12) being rotatably drivable in a first mode and being non-rotatably fixable on the machine housing (10) in a second mode, and that includes a duty-type switch (20) with a coupling element (21) capable of being displaced to activate the modes, and an actuating element (22) that induces its displacement. To prevent maloperation and resultant damage to the machine when the operator switches between modes, the actuating element is designed as an electrical actuator (23), preferably as an electromagnet (25) controlled by an electronic control unit (24) (FIG. 1).

Abstract: The invention relates to a machine tool comprising an electric motor (2) which serves to drive a tool and which has an adjustable, electric brush arrangement (3), and comprising a mode selector switch (6) having various switch positions. Provision is made for an adjusting device (8) to displace the brush arrangement (3) as a function of the switch position of the mode selector switch (6). Furthermore, the invention relates to a corresponding method.

Abstract: The present invention is based on a method for operating a guided power tool (10), in particular an electric power tool, with a rotatably and/or percussively driven insert tool (36), whereby the insert tool (36) is driven into a work piece (34) in a work process. It is proposed that at least one measured signal detected at the power tool (10) during the work process is evaluated to derive a property of the work piece (34) located in the working direction of the Insert tool (36), and the power tool (10) is operated in accordance with the property. A guided power tool is also proposed.

Abstract: A hand-held power tool, in particular a rotary hammer, is indicated that includes a machine housing (10) with a tool fitting (12) integrated therein, the tool fitting (12) being rotatably drivable in a first mode and being non-rotatably fixable on the machine housing (10) in a second mode, and that includes a duty-type switch (20) with a coupling element (21) capable of being displaced to activate the modes, and an actuating element (22) that induces its displacement. To prevent maloperation and resultant damage to the machine when the operator switches between modes, the actuating element is designed as an electrical actuator (23), preferably as an electromagnet (25) controlled by an electronic control unit (24).

Abstract: A chuck is described, in particular for a hammer drill or chisel hammer, having a chuck body having an insertion opening for holding a tool shank, and a locking element for axially locking the tool shank in the insertion opening, the locking element being movable betveen a locked position and an unlocked position, and having an arresting pin, mounted in the locking element and radially displaceable between an arresting position and a release position, which axially arrests the locking element in its arresting position and axially releases it in its release position.

Abstract: The present invention relates to a workstation for the handling of chemicals and containers, in particular of containers as used in a laboratory, in combination with a metering device for solids and liquids. The workstation comprises at least: (i) a platform, which has at least one module with at least one reservoir for a sample and at least one module with at least one target container (ii) a metering system for the metering of the sample, (iii) a portal system, which is arranged above the platform and which maneuvers the metering system to all three directions in space, (iv) a control device for controlling the movements of the metering system, and (v) a measuring system for the samples. Thereby, the metering system (ii) has a gripper device for the uptake of a metering tool and/or of the containers, and said metering tool is supported within at least one module on the platform.

Abstract: A lubricating device for lubricating a tool unit includes a lubricating unit, wherein the lubricating unit is configured for using a damming motion for lubricating the tool unit.