Patents by Inventor Andreas Termin

Andreas Termin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biaryls useful as modulators of ion channels
    Patent number: 7705002
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: April 27, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Dean Wilson, Lev T. D. Fanning, Paul Krenitsky, Pramod Joshi
  • Pyridines useful as modulators of ion channels
    Patent number: 7683065
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi
  • Isoquinolines useful as modulators of ion channels
    Patent number: 7683066
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Dean Wilson, Pramod Joshi
  • Biphenyl derivatives as modulators of voltage gated ion channels
    Patent number: 7683083
    Abstract: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: March 23, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Esther Martinborough, Danielle Lehsten, Timothy Neubert, Aarti Sameer Kawatkar, Nicole Zimmermann, Andreas Termin
  • Indane Derivatives as Modulators of ION Channels
    Publication number: 20090326023
    Abstract: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: August 31, 2009
    Publication date: December 31, 2009
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Timothy Neubert, Aarti S. Kawatkar, Esther Martinborough, Andreas Termin
  • Quinazolines useful as modulators of ion channels
    Publication number: 20090312342
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 3, 2006
    Publication date: December 17, 2009
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Lev Fanning, Timothy Neubert, Paul Krenitsky, Pramod Joshi, Dennis Hurley, Urvi Sheth
  • Indane derivatives as modulators of ion channels
    Patent number: 7605174
    Abstract: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: October 20, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Timothy Neubert, Aarti S. Kawatkar, Esther Martinborough, Andreas Termin
  • HETEROCYCLIC DERIVATIVES FOR MODULATION OF CALCIUM CHANNELS
    Publication number: 20090253682
    Abstract: Heterocyclic derivatives act as Ca channel antagonists. The compositions are useful for treating or relieving Ca channel mediated conditions.
    Type: Application
    Filed: April 16, 2009
    Publication date: October 8, 2009
    Inventors: Andreas Termin, Esther Martinborough, Nicole Zimmerman, Charles Cohen, Corey Gutierrez
  • Heterocyclic derivatives for modulation of calcium channels
    Patent number: 7569604
    Abstract: Heterocyclic derivatives act as Ca channel antagonists. The compositions are useful for treating or relieving Ca channel mediated conditions.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: August 4, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Andreas Termin, Esther Martinborough, Nicole Zimmerman, Charles Cohen, Corey Gutierrez
  • CGRP RECEPTOR ANTAGONISTS
    Publication number: 20090176769
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Application
    Filed: December 13, 2007
    Publication date: July 9, 2009
    Inventors: Corey Anderson, Andreas Termin, Sara Hadida-Ruah, Pramod Joshi, Sanghee Yoo, Daniele Bergeron, Hayley Binch, Jon Come, Jingrong Cao, Suganthi Nanthakumar, Elaine Krueger, John Maxwell, Arnaud Le Tiran, Yusheng Liao
  • AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090118333
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 7, 2009
    Inventors: Weichuan Caroline Chen, Paul Krenitsky, Andreas Termin, Dean Wilson
  • ARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090118338
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 7, 2009
    Inventors: Weichuan Caroline Chen, Paul Krenitsky, Pramod Joshi, Andreas Termin, Dean Wilson
  • HETEROARYL AMIDES USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20090099233
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 10, 2008
    Publication date: April 16, 2009
    Inventors: Pramod Joshi, Paul Krenitsky, Andreas Termin, Dean Wilson
  • Bicyclic derivatives as modulators of ion channels
    Publication number: 20090012117
    Abstract: Bicyclic derivatives having formula (I) and a composition thereof are useful as ion channel antagonists:
    Type: Application
    Filed: May 8, 2006
    Publication date: January 8, 2009
    Inventors: Aarti S. Kawatkar, Tara M. Whitney, Timothy D. Neubert, Nicole Zimmermann, Andreas Termin, Esther Martinborough
  • Heterocycles useful as modulators of ion channels
    Publication number: 20080255147
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 26, 2006
    Publication date: October 16, 2008
    Inventors: Dean Wilson, Andreas Termin, Lev T.D. Fanning, Paul Krenitsky, Pramod Joshi
  • Quinazolines useful as modulators of voltage gated ion channels
    Publication number: 20080221137
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 13, 2006
    Publication date: September 11, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • QUINAZOLINES USEFUL AS MODULATORS OF VOLTAGE GATED ION CHANNELS
    Publication number: 20080167305
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: March 18, 2008
    Publication date: July 10, 2008
    Inventors: Dean Wilson, Lev T.D. Fanning, Paul Krenitsky, Andreas Termin, Pramod Joshi, Urvi Sheth
  • Bicyclic derivatives as modulators of ion channels
    Publication number: 20080119453
    Abstract: The present invention relates to bicyclic compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 12, 2006
    Publication date: May 22, 2008
    Inventors: Andreas Termin, Nicole Zimmermann, Tara Leanne Knoll, Gabriel Martinez Botella, Esther Martinborough
  • Biphenyl derivatives as modulators of voltage gated ion channels
    Publication number: 20080113990
    Abstract: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
    Type: Application
    Filed: October 12, 2006
    Publication date: May 15, 2008
    Inventors: Esther Martinborough, Danielle Lehsten, Timothy Neubert, Aarti Sameer Kawatkar, Nicole Zimmermann, Andreas Termin
  • Biaryls useful as modulators of ion channels
    Publication number: 20080090837
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 15, 2006
    Publication date: April 17, 2008
    Inventors: Andreas Termin, Dean Wilson, Lev Fanning, Paul Krenitsky, Pramod Joshi