Patents by Inventor Andreas Termin

Andreas Termin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of muscarinic receptors
    Publication number: 20080015179
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: December 22, 2006
    Publication date: January 17, 2008
    Inventors: Lewis Makings, Miguel Blanco, Dennis Hurley, Ioana Drutu, Gabriel Raffai, Daniele Bergeron, Akiko Nakatani, Andreas Termin, Alina Silina
  • CGRP receptor antagonists
    Publication number: 20080004261
    Abstract: The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions.
    Type: Application
    Filed: June 13, 2007
    Publication date: January 3, 2008
    Inventors: Corey Gutierrez, Andreas Termin, Sara Hadida-Ruah, Pramod Joshi, Daniele Bergeron, Sanghee Yoo, Hayley Binch, Jon Come, Jingrong Cao, Suganthi Nanthakumar
  • Thienopyrimidines useful as modulators of ion channels
    Publication number: 20070287717
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: June 12, 2007
    Publication date: December 13, 2007
    Inventors: Lev Fanning, Pramod Joshi, Paul Krenitsky, Andreas Termin, Dean Wilson, Yulian Zhang
  • Heteroaromatic substituted cyclopropane as corticotropin releasing hormone ligands
    Patent number: 7297708
    Abstract: Provided herein are novel heteroaromatic substituted cyclopropanes of the Formula (I): as well as compositions, including pharmaceutical compositions, containing the same, and the use thereof in the treatment of various neurological and psychological disorders, e.g., anxiety and depression, treatable by antagonizing CRF receptors.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: November 20, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andreas Termin, Peter D. J. Grootenhuis, Dean M. Wilson, Valentina Molteni, Long Mao, Angelo Castellino, Zhicai Yang, Anthony Pechulis, Mark Suto
  • Compositions useful as inhibitors of voltage-gated sodium channels
    Publication number: 20070238733
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: April 11, 2007
    Publication date: October 11, 2007
    Inventors: Pramod Joshi, Paul Krenitsky, Jesus Gonzalez, Jian Wang, Dean Wilson, Andreas Termin
  • Substituted thiazoles and oxazoles as corticotropin releasing hormone ligands
    Patent number: 7276526
    Abstract: Provided herein are novel substituted thiazoles and oxazoles of the Formula (I): as well as compositions, including pharmaceutical compositions, containing the same, and the use thereof in the treatment of various neurological and psychological disorders, e.g., affective disorder, anxiety and depression, treatable by antagonizing CRF receptors.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: October 2, 2007
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Andreas Termin, Peter Grootenhuis, Dean Wilson, Valentina Molteni, Long Mao
  • Bicyclic derivatives as modulators of voltage gated ion channels
    Publication number: 20070203130
    Abstract: Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
    Type: Application
    Filed: September 8, 2006
    Publication date: August 30, 2007
    Inventors: Timothy Neubert, Nicole Zimmermann, Esther Martinborough, Aarti Kawatkar, Andreas Termin
  • Derivatives for modulation of ion channels
    Publication number: 20070203122
    Abstract: Sulfonamide derivatives act as ion channel antagonists. The compositions are useful for treating or relieving pain-related conditions.
    Type: Application
    Filed: October 23, 2006
    Publication date: August 30, 2007
    Inventors: Esther Martinborough, Andreas Termin, Timothy Neubert, Nicole Zimmermann, Corey Gutierrez
  • Indane derivatives as modulator of ion channels
    Publication number: 20070117801
    Abstract: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: June 9, 2006
    Publication date: May 24, 2007
    Inventors: Timothy Neubert, Aarti Kawatkar, Esther Martinborough, Andreas Termin
  • Quinolines useful as modulators of ion channels
    Publication number: 20070099873
    Abstract: The present invention relates to compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 15, 2006
    Publication date: May 3, 2007
    Inventors: Andreas Termin, Dean Wilson, Pramod Joshi
  • Pyrimidines and pyrazines useful as modulators of ion channels
    Publication number: 20070093454
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 4, 2006
    Publication date: April 26, 2007
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi, Urvi Sheth
  • Pyridines useful as modulators of ion channels
    Publication number: 20070082889
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: May 4, 2006
    Publication date: April 12, 2007
    Inventors: Dean Wilson, Andreas Termin, Dewey Fanning, Paul Krenitsky, Pramod Joshi
  • Modulators of muscarinic receptors
    Publication number: 20070043023
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: February 22, 2006
    Publication date: February 22, 2007
    Inventors: Lewis Makings, Miguel Blanco, Dennis Hurley, Ioana Drutu, Gabriel Raffai, Daniele Bergeron, Akiko Nakatani, Andreas Termin, Alina Silina
  • Quinazolines useful as modulators of ion channels
    Publication number: 20060217377
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: September 2, 2004
    Publication date: September 28, 2006
    Inventors: Jesus Gonzalez, Dean Wilson, Andreas Termin, Peter Grootenhuis, Yulian Zhang, Benjamin Petzoldt, Lev Fanning, Timothy Neubert, Roger Tung, Esther Martinborough, Nicole Zimmerman
  • Quinazolines useful as modulators of ion channels
    Publication number: 20060173018
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: August 31, 2005
    Publication date: August 3, 2006
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Lev Fanning, Timothy Neubert, Paul Krenitsky, Pramod Joshi, Dennis Hurley, Urvi Sheth
  • Modulators of muscarinic receptors
    Publication number: 20060079505
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: August 19, 2005
    Publication date: April 13, 2006
    Applicant: VERTEX PHARMACEUTICALS, INCORPORATED
    Inventors: Lewis Makings, Miguel Blanco, Dennis Hurley, Ioana Drutu, Gabriel Raffai, Daniele Bergeron, Akiko Nakatani, Andreas Termin, Alina Silina
  • Heterocyclic derivatives for modulation of calcium channels
    Publication number: 20060074076
    Abstract: Heterocyclic derivatives act as Ca channel antagonists. The compositions are useful for treating or relieving Ca channel mediated conditions.
    Type: Application
    Filed: June 22, 2005
    Publication date: April 6, 2006
    Inventors: Andreas Termin, Esther Martinborough, Nicole Zimmerman, Charles Cohen, Corey Gutierrez
  • Carboxylic acid substituted heterocycles, derivatives thereof and methods of use
    Patent number: 7022690
    Abstract: Selected novel carboxylic acid substituted heterocycle compounds are effective for prophylaxis and treatment of inflammation, tissue degradation, cancer, fibrosis and related diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of inflamation, tissue degradation and related diseases. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: April 4, 2006
    Assignee: Amgen Inc.
    Inventors: Kevin Koch, Andreas Termin, John A. Josey
  • Compositions useful as inhibitors of voltage-gated sodium channels
    Publication number: 20060025415
    Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: February 17, 2005
    Publication date: February 2, 2006
    Inventors: Jesus Gonzalez, Andreas Termin, Esther Martinborough, Nicole Zimmerman
  • Benzimidazoles useful as modulators of ion channels
    Publication number: 20050209282
    Abstract: The present invention relates to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the R1, Z, Y, RA, and W groups of formula I are as defined herein. The invention also provides pharmaceutically acceptable compositions and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: October 28, 2004
    Publication date: September 22, 2005
    Inventors: Dean Wilson, Andreas Termin, Jesus Gonzalez, Nicole Zimmermann, Yulian Zhang, Lev Fanning