Abstract: The present invention discloses a method of generating subsets of methylation specific markers from a set, having diagnostic power for various diseases, e.g. cancer of thyroid, breast, colon, or leukemia, in diverse samples; identified subsets of that set, as well as methods for the prognosis and diagnosis of diseases.

Abstract: A method is provided of diagnosing prostate cancer or the risk of prostate cancer in a patient by detecting antibodies against the following marker proteins or a selection of at least 2 or at least 20% of the marker proteins of any List provided herein in a patient, including the step of detecting antibodies binding the marker proteins in a sample of the patient; and systems and kits for such methods.

Abstract: The present invention discloses a method of diagnosing lung cancer by using specific markers from a set, having diagnostic power for lung cancer diagnosis and distinguishing lung cancer types in diverse samples.

Abstract: The present invention relates to specifically methylated nucleic acids, methods of diagnosing lung cancer or a predisposition therefor, and a corresponding kit.

Abstract: The invention provides method of identifying a colorectal cancer in a sample comprising DNA from a subject, determining the methylation status of one or more of the genes selected from BOLL, CDX1, CLIC4, DCC, ESR1, GATA4, GDNF, HLA-G, JUB, MYOD1, NKX2-1, PENK, PITX2, PTGS2, RARB, S100A2, SALL3, SEZ6L, SFRP2, SPARC, TCEB2, TFPI2, THBD, TJP2, TMEFF2, TP53, TWIST1, WT1 or combinations thereof and comparing the methylation status with a control, thereby identifying colorectal cancer DNA in the sample and means for performing the inventive method.

Abstract: The present invention discloses a method of diagnosing breast cancer by using specific markers from a set, having diagnostic power for breastcancer diagnosis and distinguishing breastcancer types in diverse samples.

Abstract: The present invention discloses a method of diagnosing lung cancer by using methylation specific markers from a set, having diagnostic power for lung cancer diagnosis and distinguishing lung cancer types in diverse samples; as well as methods to identify sets of prognostic and diagnostic value.

Abstract: The present invention discloses a method of diagnosing lung cancer by using specific markers from a set, having diagnostic power for lung cancer diagnosis and distinguishing lung cancer types in diverse samples.

Abstract: The present invention discloses a method of diagnosing colon cancer by using specific markers from a set, having diagnostic power for colon cancer diagnosis and distinguishing colon cancer types in diverse samples.

Abstract: The present invention discloses a method of diagnosing lung cancer by using methylation specific markers from a set, having diagnostic power for lung cancer diagnosis and distinguishing lung cancer types in diverse samples; as well as methods to identify sets of prognostic and diagnostic value.

Abstract: The present invention discloses a method of generating subsets of methylation specific markers from a set, having diagnostic power for various diseases, e.g. cancer of thyroid, breast, colon, or leukemia, in diverse samples; identified subsets of that set, as well as methods for the prognosis and diagnosis of diseases.

Abstract: A method for detecting and evaluating a potentially aberrantly methylated DNA region on the X chromosome, or the clonality, wherein the extent of methylation of the potentially aberrantly methylated DNA region and optionally the extent of methylation in a definitely physiologically methylated DNA region of the X chromosome and/or the extent of methylation as well as optionally the sequence variant of a polymorphous DNA region of the X chromosome, which may either be physiologically or aberrantly methylated, are determined in a sample and the presence and optionally the variant and the extent of the potential aberration, or the clonality, are subsequently diagnosed from the comparison of the methylation determinations and optionally the sequence variant.