Patents by Inventor Andreas WIRTH
Andreas WIRTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9284525Abstract: The invention relates to a method for the application of at least one voltage pulse to at least two containers fitted with electrodes, by means of which at least one voltage pulse is applied to at least one container, while at least one other container is subjected to a preparation or a post-processing. According to the invention the method comprises mutual exchange of the respective positions of the container to which a voltage pulse has already been applied and the further container. Furthermore, the invention relates to a device (1) for making electrical contact with at least one container fitted with electrodes, with at least one receptacle (3, 7) upon which at least one container can be set, and with at least one contact appliance (8) for making contact with the electrodes of the container.Type: GrantFiled: January 20, 2010Date of Patent: March 15, 2016Assignee: LONZA COLOGNE GMBHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Müller-Hartmann, Andreas Wirth
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Patent number: 9249384Abstract: The invention relates to a method for applying at least one electrical voltage pulse to at least one reaction space by at least partially discharging at least one charge storing unit for storing electrical charges. According to the invention the method comprises applying at least one voltage pulse to a reaction space by at least partially discharging a second charge storing unit and simultaneously charging or partially discharging a first charge storing. Furthermore, the invention relates to a device 1 for applying at least one electrical voltage pulse to at least one reaction space, comprising at least two charge storing units (10, 11) for storing electrical charges and at least one power supply unit (12) for charging the charge storing units (10, 11) and/or at least one discharge device for partially discharging the charge storing units (10, 11). According to the invention it is provided that at least two of the charge storing units (10, 11) form a common storage module which can be discharged at any time.Type: GrantFiled: January 20, 2010Date of Patent: February 2, 2016Assignee: LONZA COLOGNE GMBHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Müller-Hartmann, Andreas Wirth
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Patent number: 9080139Abstract: The invention relates to a container (1) with at least three reaction spaces (2) which in each case have at least one electrode pair for applying an electric voltage for generating an electric field within the reaction space (2) and which are arranged geometrically in at least one row and/or electrically connected in at least one row, wherein at least one electrode (3, 4) of a reaction space (2) is a common electrode (3, 4) with at least one other reaction space (2). According to the invention n+x electrodes (3, 4, 5) are provided, wherein n is the number of reaction spaces (2), with n?3 and x is the number of rows, with x?1.Type: GrantFiled: January 20, 2010Date of Patent: July 14, 2015Assignee: LONZA COLOGNE GMBHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Mueller-Hartmann, Andreas Wirth
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Publication number: 20130260434Abstract: The invention relates to an electrode assembly 20, in particular for applying at least one electric field to adherent cells, comprising at least two electrodes 21, each having at least one surface 32 which is arranged opposite the corresponding surface 32 of the other electrode 21, wherein an electrically insulating material 26 is arranged at least partially between the surfaces 32 of the electrodes 21. The solution according to the invention allows the electric field to be concentrated in the region of the cells to be treated such that a voltage pulse, or the current produced thereby, flows through the cells without the majority flowing away over the cells unused in the electrolyte.Type: ApplicationFiled: June 21, 2011Publication date: October 3, 2013Applicant: LONZA COLOGNE GMBHInventors: Herbert Mueller-Hartmann, Andreas Wirth
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Publication number: 20130230895Abstract: The invention relates to a method for subjecting adherent cells to at least one electric field, in which the electric field is generated by applying a voltage to at least two active electrodes 63, wherein at least three electrodes 63, 64 are provided, and wherein at least two electrodes 63, 64 are active electrodes 63 when the voltage is applied in order to generate a first electric field, and in which at least one second electric field is generated, wherein at least one of the two previously active electrodes 63 is a potential-free electrode 64 when the voltage is applied.Type: ApplicationFiled: June 21, 2011Publication date: September 5, 2013Applicant: LONZA COLOGNE GMBHInventors: Thomas Koblizek, Andreas Heinze, Timo Gleissner, Herbert Mueller-Hartmann, Andreas Wirth
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Patent number: 8450102Abstract: A device 1 with at least one electrode 8 for generating an electrical field in a chamber 7 is disclosed. The device 1 comprises at least one input channel 6 for introducing a fluid into the chamber 7, and at least one output channel 11 for discharging the fluid from the chamber 7. Also disclosed is a method for stabilizing the flow of a fluid through a chamber 7 in which an electrical field is generated and which has at least one input channel 6 for introducing the fluid into the chamber and at least one output channel 11 for discharging the fluid from the chamber 8. To avoid undesirable backflow of the fluid due to gas formation, the average inside diameter of the input channel 6 of device 1 is smaller than the average inside diameter of the output channel 11.Type: GrantFiled: February 22, 2008Date of Patent: May 28, 2013Assignee: Lonza Cologne GmbHInventors: Andreas Wirth, Michael Kazinski
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Publication number: 20120214708Abstract: The invention relates to a measuring device for measuring at least one property of cells or vesicles, characterized in that is divided into two chambers by a hydrophobic partition having a horizontal opening, these chambers containing electrolyte solution and said opening being closed by a lipid double layer. The invention is characterized in that at least one cell or vesicle contacts the lipid double layer. The invention also relates to methods involving the use of the measuring device and to arrays, measuring chambers and microtitration plates all suited therefor.Type: ApplicationFiled: December 22, 2011Publication date: August 23, 2012Applicant: Universitat OsnabruckInventors: Richard Wagner, Karsten Gall, Andreas Wirth
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Publication number: 20120087841Abstract: The invention relates to a container (1) with at least three reaction spaces (2) which in each case have at least one electrode pair for applying an electric voltage for generating an electric field within the reaction space (2) and which are arranged geometrically in at least one row and/or electrically connected in at least one row, wherein at least one electrode (3, 4) of a reaction space (2) is a common electrode (3, 4) with at least one other reaction space (2). According to the invention n+x electrodes (3, 4, 5) are provided, wherein n is the number of reaction spaces (2), with n?3 and x is the number of rows, with x?1.Type: ApplicationFiled: January 20, 2010Publication date: April 12, 2012Applicant: LONZA COLOGNE GMBHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Mueller-Hartmann, Andreas Wirth
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Publication number: 20120077245Abstract: The invention relates to a method for applying at least one electrical voltage pulse to at least one reaction space by at least partially discharging at least one charge storing unit for storing electrical charges. According to the invention the method comprises applying at least one voltage pulse to a reaction space by at least partially discharging a second charge storing unit and simultaneously charging or partially discharging a first charge storing. Furthermore, the invention relates to a device 1 for applying at least one electrical voltage pulse to at least one reaction space, comprising at least two charge storing units (10, 11) for storing electrical charges and at least one power supply unit (12) for charging the charge storing units (10, 11) and/or at least one discharge device for partially discharging the charge storing units (10, 11). According to the invention it is provided that at least two of the charge storing units (10, 11) form a common storage module which can be discharged at any time.Type: ApplicationFiled: January 20, 2010Publication date: March 29, 2012Applicant: LONZA COLOGNE GmbHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Müller-Hartmann, Andreas Wirth
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Publication number: 20120067639Abstract: The invention relates to a method for the application of at least one voltage pulse to at least two containers fitted with electrodes, by means of which at least one voltage pulse is applied to at least one container, while at least one other container is subjected to a preparation or a post-processing. According to the invention the method comprises mutual exchange of the respective positions of the container to which a voltage pulse has already been applied and the further container. Furthermore, the invention relates to a device (1) for making electrical contact with at least one container fitted with electrodes, with at least one receptacle (3, 7) upon which at least one container can be set, and with at least one contact appliance (8) for making contact with the electrodes of the container.Type: ApplicationFiled: January 20, 2010Publication date: March 22, 2012Applicant: LONZA COLOGNE GmbHInventors: Ludger Altrogge, Timo Gleissner, Andreas Heinze, Herbert Müller-Hartmann, Andreas Wirth
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Publication number: 20090023600Abstract: The invention relates to a measuring device for measuring at least one property of cells or vesicles, characterized in that is divided into two chambers by a hydrophobic partition having a horizontal opening, these chambers containing electrolyte solution and said opening being closed by a lipid double layer. The invention is characterized in that at least one cell or vesicle contacts the lipid double layer. The invention also relates to methods involving the use of the measuring device and to arrays, measuring chambers and microtitration plates all suited therefor.Type: ApplicationFiled: November 4, 2005Publication date: January 22, 2009Applicant: Universitat OsnabruckInventors: Richard Wagner, Karsten Gall, Andreas Wirth
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Publication number: 20080213854Abstract: A device 1 with at least one electrode 8 for generating an electrical field in a chamber 7 is disclosed. The device 1 comprises at least one input channel 6 for introducing a fluid into the chamber 7, and at least one output channel 11 for discharging the fluid from the chamber 7. Also disclosed is a method for stabilising the flow of a fluid through a chamber 7 in which an electrical field is generated and which has at least one input channel 6 for introducing the fluid into the chamber and at least one output channel 11 for discharging the fluid from the chamber 8. To avoid undesirable backflow of the fluid due to gas formation, the average inside diameter of the input channel 6 of device 1 is smaller than the average inside diameter of the output channel 11.Type: ApplicationFiled: February 22, 2008Publication date: September 4, 2008Applicant: amaxa AGInventors: Andreas WIRTH, Michael KAZINSKI