Abstract: The invention relates to a linear motor system, in particular a transport system, e.g. a multicarrier, having at least one carrier, having a guide track for the carrier, having a guide rail arranged at the guide track, and having a guide element arranged at the carrier, wherein the guide rail and the guide element cooperate to guide the carrier at the guide track, wherein a magnet is provided at the carrier and a magnet is provided at the guide track for driving the carrier along the guide track and/or for holding the carrier at the guide track, wherein a y direction extends in parallel with a spacing between the magnets, wherein the guide track comprises a contact surface which the guide rail contacts, and wherein a normal of the contact surface extends with at least one component in parallel with the y direction.

Abstract: A system for the functionalization of polyolefin fiber includes a reactor chamber, a fiber pulley system, and a precursor sprinkler system. The reactor chamber defines an interior reactor space and a plurality of fiber inlet/outlet pairs positioned at opposite ends of respective fiber processing axes. The fiber pulley system is arranged to direct polyolefin fiber through the plurality of fiber inlet/outlet pairs, along a fiber processing path comprising the respective fiber processing axes. The precursor sprinkler system is operable to aerosolize a precursor solution and contact the aerosolized precursor solution with the polyolefin fiber.

Abstract: A structure comprises: a plurality of substructures and a vernier-based position marker. The plurality of substructures include a first substructure, a second substructure, and at least one electronic component. The second substructure is at least partially additively manufactured on the first substructure. The vernier-based position marker is configured to indicate a relative offset between the first substructure and the second substructure.

Abstract: A method of treatment or prevention of HIV and other viral infection comprising the administration of a biopolymer-based hydrogel nanoparticles and/or microparticles. In preferred embodiments, the particles comprise chitosan, hydroxyethyl cellulose (HEC), and linseed oil polyol. These biopolymer-based hydrogel nanoparticles and/or microparticles are antiviral agents that can be employed alone or in combination with other drugs for treatment of the viral infection. Further, the pre-treatment with the particles is highly effective at inhibiting viruses. Therefore, this antiviral biopolymer-based hydrogel nanoparticles and/or microparticles may also be employed as a prophylactic.

Abstract: A molding tool (1000), in particular a thermoforming tool, for producing a container (10) is provided. The molding tool comprises a mold bottom (200) and a mold insert (100) receiving the mold bottom (200), wherein the mold insert (100) is constructed of at least two mold insert parts (110, 120) that together with the mold bottom (200) define a cavity (300) provided for reshaping a two-dimensional web of material into a container, wherein a first mold insert part (110) is mounted stationary in the molding tool (1000) and a second mold insert part is axially movable in the molding tool (1000).

Abstract: In an embodiment a sensor system includes a first sensor having a first thermistor configured to sense a change in heat flow and a first heater configured to heat the first thermistor and a second sensor having a second thermistor configured to sense a change in heat flow and a second heater configured to heat the second thermistor, wherein a heat conduction path between the first heater and the first thermistor has a higher thermal conductivity than a heat conduction path between the second heater and the second thermistor.

Abstract: The present invention relates to a bacterial strain of Bifidobacterium bifidum MIMBb23 sg (=BbfIBSCM) DSM 32708, compositions comprising said bacterial strain and the use thereof in methods for the treatment of gastrointestinal disorders, in particular functional gastrointestinal disorders, such as, for example, irritable bowel syndrome (IBS) or inflammatory bowel diseases (IBDs).

Abstract: A method for operating a system for electrolysis in order to obtain at least one gaseous electrolysis product, in which system at least one electrolysis device is electrically connected to a power converter by means of a direct-voltage circuit, the power converter being connected to an alternating-voltage circuit in order to supply the at least one electrolysis device with electrically energy for the operation of the at least one electrolysis device, the power converter being operated by means of zero crossing control. The invention further relates to a system of this type.

Abstract: An electric machine (1), comprising: a housing (2), in which a stator (3) and a rotor (4), which is rotatable relative to the stator (3), are accommodated, a cooling device with a cooling channel (5) through which a coolant can flow and which extends from an inlet (7), through the housing (2) and through the rotor (4), to an outlet (6), and a sealing device (21) for sealing off the rotor (4) with respect to an interior space (22) of the housing, wherein an end section of the rotor (4) is surrounded by a sleeve (10), which is surrounded by a radial shaft sealing ring (11) of the sealing device (21). Additionally described are a drivetrain for a vehicle (17), a vehicle (17) of said type, and a method for operating the electric machine (1).

Abstract: The present disclosure provides methods of treating a subject having metabolic disorders and/or cardiovascular diseases, methods of identifying subjects having an increased risk of developing a metabolic disorder and/or a cardiovascular disease, and methods of detecting human Inhibin Subunit Beta E variant nucleic acid molecules and variant polypeptides.

Abstract: Method to process data, in particular to assess a financial risk relating to a financial transaction that occurs between an investor and one or more counterparts.

Abstract: A water-soluble multicompartment unit dose article having a weight ratio of laundry detergent to total water-soluble film in the water-soluble multicompartment unit dose article of at least 45:1.

Abstract: The invention relates to a method for handling products (17) using an automation system and to an automation system (10), the products being captured by means of an imaging sensor (18) of a control device (12) of the automation system and being handled by means of a handling mechanism (13) of a handling device (11) of the automation system, the control device processing sensor image data from the imaging sensor and controlling the handling device as specified by training data sets contained in a data memory (21) of the control device, the training data sets comprising training image data and/or geometric data and control instructions associated therewith, the training data sets being generated, as a statistical model, exclusively from geometric data contained in the training image data of products, by means of a computer using a computer program product executed thereon, the training data sets being transmitted to the control device.

Abstract: A circuit arrangement for charge integration may include an input for applying a signal representing charge pulses, an output for providing an integrated signal, and an integrating circuit connected between the input and the output, comprising a resistive circuit and a capacitor and having an RC time constant which is a function of the resistive circuit and the capacitor. The circuit arrangement may include a feedback control circuit connected at its input, to the output of the circuit arrangement and providing, at its output, a control signal, where at least one of the resistive circuit and the capacitor has a variable value based on the control signal.

Abstract: A wireless communication device (12) conditions its use of Preconfigured Uplink Resources (PUR), as preconfigured by a wireless communication network (16), on assessing the validity of a Timing Advance (TA) value used by the device (12) for controlling its uplink transmission timing The device (12) maintains a timer (37) and deems the TA value to be invalid upon expiration of the timer (37). In an example case, a device (12) operating in idle mode performs a PUR-based transmission in dependence on the timer (37) not being expired. A radio network node (10) of the network (16) maintains a like timer (57), to maintain an awareness of TA validity at the device (12) and, for example, sends an updated TA for the device (12) upon receiving a PUR-based transmission from the device (12). The device (12) and the node (10) may refresh their respective timers, in association with the TA update.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.

Abstract: A device for generating alerts for Hypo and Hyperglycemia Prevention from Continuous Glucose Monitoring (CGM) determines a dynamic risk based on both information of glucose level and a trend obtainable from a CGM signals. The device includes a display whose color depends on the DR (for example, red for high DR, green for low risk). When DR exceeds a certain threshold, alerts are generated to suggest the patient to pay attention to the current glucose reading and to its trend, both of which are shown on the display in numbers and symbols (e.g. an arrow with different slope or color).

Abstract: An apparatus for a firing mechanism 102 for use in an injection device 100 and comprising: a rear cap 104 having an elongate member 110 extending axially forwards when installed within the injection device; a plunger 106 releasably connected, directly or indirectly, to the elongate member and, upon release of the connection to the elongate member, axially displaceable in a forward direction; and a plunger driver 112 to drive the plunger axially forwards upon release of the connection to the elongate member, wherein the plunger and the rear cap define an axial length of the assembly, which in turn determines a start position of a forward end of the plunger before release of the connection to the elongate member, and wherein, during construction of the assembly, the plunger is releasably connectable, directly or indirectly, to the elongate member at one of a plurality of positions for controlling the axial length of the assembly.

Abstract: The present disclosure relates to a calculation device for determining an interdialytic sodium intake of a patient and/or for determining a non-osmotically triggered interdialytic liquid intake, including a storage device and/or an input device configured for storing or for entering parameter values of the patient; a computing device, configured for calculating the interdialytic sodium intake of the patient and/or for calculating his non-osmotically triggered interdialytic liquid intake; and an output device for outputting a signal for controlling or closed-loop controlling a communication device and/or a medical blood treatment apparatus.

Abstract: The present invention relates to transgenic plants with altered photorespiration and improved CO2 fixation as well as a method of producing said transgenic plants. Particularly, the transgenic plants show an improved growth rate, productivity and energy conversion efficiency. This method can be successfully applied to many agricultural crop plants with nutritional and medicinal uses.