Patents by Inventor Andrei V. Gudkov

Andrei V. Gudkov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10898543
    Abstract: The use of flagellin and flagellin related polypeptide for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: January 26, 2021
    Assignee: Cleveland Clinic Foundation
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20200392190
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 17, 2020
    Inventors: Andrei V. GUDKOV, Vadim METT, Vadim KRIVOKRYSENKO
  • Publication number: 20200261535
    Abstract: The use of flagellin and flagellin related polypeptide for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: November 26, 2019
    Publication date: August 20, 2020
    Inventors: Andrei V. GUDKOV, Joseph A. DIDONATO, Vadim KRIVOKRYSENKO
  • Patent number: 10730915
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: August 4, 2020
    Assignee: Genome Protection, Inc.
    Inventors: Andrei V. Gudkov, Vadim Mett, Vadim Krivokrysenko
  • Patent number: 10543251
    Abstract: The use of flagellin and flagellin related polypeptide for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: January 28, 2020
    Assignee: Cleveland Clinic Foundation
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20190381139
    Abstract: The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-?B activity. The modulators may be used, for example, in the treatment of NF-?B-mediated diseases, conditions, and injuries.
    Type: Application
    Filed: July 31, 2019
    Publication date: December 19, 2019
    Inventor: Andrei V. GUDKOV
  • Publication number: 20190315810
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Application
    Filed: May 16, 2019
    Publication date: October 17, 2019
    Inventors: Andrei V. GUDKOV, Vadim METT, Vadim KRIVOKRYSENKO
  • Patent number: 10406206
    Abstract: The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-?B activity. The modulators may be used, for example, in the treatment of NF-?B-mediated diseases, conditions, and injuries.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: September 10, 2019
    Assignee: The Cleveland Clinic Foundation
    Inventor: Andrei V. Gudkov
  • Patent number: 10336793
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: July 2, 2019
    Assignee: GENOME PROTECTION, INC.
    Inventors: Andrei V. Gudkov, Vadim Mett, Vadim Krivokrysenko
  • Publication number: 20190151407
    Abstract: The use of flagellin and flagellin related polypeptide for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: August 24, 2018
    Publication date: May 23, 2019
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20180354995
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 13, 2018
    Inventors: Andrei V. Gudkov, Vadim Mett, Vadim Krivokrysenko
  • Patent number: 10086038
    Abstract: The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: October 2, 2018
    Assignee: CLEVELAND CLINIC FOUNDATION
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20180140663
    Abstract: The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: October 26, 2017
    Publication date: May 24, 2018
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Patent number: 9827289
    Abstract: The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: November 28, 2017
    Assignee: CLEVELAND CLINIC FOUNDATION
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20170266278
    Abstract: The present invention relates to, in part, compositions comprising improved flagellin derived constructs and methods of using for vaccination, including adjuvants comprising flagellin-based agents.
    Type: Application
    Filed: July 30, 2015
    Publication date: September 21, 2017
    Inventors: Andrei V. GUDKOV, Vadim METT, Vadim KRIVOKRYSENKO
  • Publication number: 20170128533
    Abstract: The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-?B activity. The modulators may be used, for example, in the treatment of NF-?B-mediated diseases, conditions, and injuries.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 11, 2017
    Inventor: Andrei V. Gudkov
  • Publication number: 20170080051
    Abstract: The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 23, 2017
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Patent number: 9585939
    Abstract: The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-?B activity. The modulators may be used, for example, in the treatment of NF-?B-mediated diseases, conditions, and injuries.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: March 7, 2017
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Andrei V. Gudkov
  • Patent number: 9457061
    Abstract: The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: October 4, 2016
    Assignee: Cleveland Clinic Foundation
    Inventors: Andrei V. Gudkov, Joseph A. DiDonato, Vadim Krivokrysenko
  • Publication number: 20160213714
    Abstract: Provided are compositions and methods for aiding in healing of a tissue wound in an individual. The method generally entail delivering to an individual in need thereof senescent cells such that healing of the wound is accelerated. The disclosure includes use of senescent cells and senescent tumor cells, either of which may be allogeneic or autologous to the individual. Also provided are methods for inducing senescence in cells and using the cells for wound healing, and articles of manufacture comprising senescent cells for use in wound healing.
    Type: Application
    Filed: January 25, 2016
    Publication date: July 28, 2016
    Inventors: Andrei V. Gudkov, Olga Chernova, Brandon Hall