Abstract: Systems and methods for monitoring a fleet of self-driving vehicles are disclosed. The system comprises one or more self-driving vehicles having at least one sensor for collecting current state information, a fleet-management system, and computer-readable media for storing reference data. The method comprises autonomously navigating a self-driving vehicle in an environment, collecting current state information using the vehicle's sensor, comparing the current state information with the reference data, identifying outlier data in the current state information, and generating an alert based on the outlier data. A notification based on the alert may be sent to one or more monitoring devices according to the type and severity of the outlier.

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Abstract: A computer-implemented method (200) of managing a telecommunications network (110), the telecommunication network comprising a network orchestrator (120), a plurality of network nodes (150) and a network ledger (140) for electronically storing data, the method comprising the steps of: the network orchestrator generating an instruction for reconfiguring at least one of the plurality of nodes (210); in response to generating said instruction, requesting and retrieving first status information from the at least one of the plurality of nodes (240); recording the instruction and the first status information to the network ledger (240)); communicating the instruction to the at least one of the plurality of nodes thereby to effect the instructed reconfiguration (230); in response to effecting the instructed reconfiguration, requesting and retrieving second status information from the at least one of the plurality of nodes; and recording said second status information in the network ledger (280).

Abstract: A non-powered insect repellent device can include a heating element, a removable cover, an insect repellent element, and a housing. The heating element can include a chemical compound configured to generate heating energy via an exothermic reaction. The removable cover can be coupled with a portion of the heating element. The portion of the heating element can be exposed to air with the removable cover at least partially removed from the heating element. The insect repellent element can emanate insect repellent solution in response to the heating energy. The housing can define a cavity, a first opening, and a second opening. Air can flow through the first opening to the heating element. The housing is configured to provide vaporized insect repellent solution through the second opening.

Abstract: A wake-up radio system in a wireless sensor network, the wake-up radio comprising: an analog front end configured to communicate with matching network; an analog to digital converter coupled to the analog front end; and a digital baseband coupled to the analog to digital converter, wherein the digital baseband outputs a fast wake-up signal and a secure wake-up signal, and wherein the wake-up radio listens to all channels simultaneously.

Abstract: A mass spectrometer is disclosed comprising a rotatable isolation valve 1 having a curved, spherical, cylindrical or concave portion. At least a portion of an ion guide 2 is positioned so as to extend within a swept volume of the isolation valve 1 enabling the ion guide 2 to be positioned close to a second downstream ion guide 3 and for ions to be transmitted from the first 2 ion guide to the second ion guide 3 with high ion transmission efficiency.

Abstract: Polypeptides are provided that have activity at each of the GIP, GLP-1 and glucagon receptors. The polypeptides have structural features resulting in activity and extended duration of action at each of these receptors. Methods also are provided for treating diseases and/or conditions such as obesity, chronic weight management, type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), dyslipidemia, metabolic syndrome, Chronic Kidney Disease (CKD), osteoarthritis (OA), obesity-related sleep apnea (OSA) and polycystic ovary syndrome (PCOS).

Abstract: In one example, an unsaturated cyclic dione is coupled to the substrate, and is reacted with an indole or indazole including a first functional group to form a first adduct coupling the first functional group to the substrate. In another example, an unsaturated cyclic dione is coupled to a substrate and reacted with a diene including a functional group to form an adduct coupling the functional group to the substrate. In another example, an indole or indazole is coupled to a substrate, and is reacted with an unsaturated cyclic dione including an oligonucleotide to form an adduct coupling the oligonucleotide to the substrate. In another example, a diene is coupled to a substrate, and is reacted with an unsaturated cyclic dione including an oligonucleotide to form an adduct coupling the oligonucleotide to the substrate.

Abstract: Systems and methods for operating a fluid supply system. The methods comprise: using a micro-turbine and an Energy Harvesting Circuit (“EHC”) to harvest energy from a fluid flowing through a pipeline; operating a switch to disconnect the EHC from the micro-turbine when an amount of energy harvested reaches a threshold value; detecting by a sensor device an amount of natural fluid flow through the pipeline while the EHC is disconnected from the micro-turbine; and operating the switch to reconnect the EHC to the micro-turbine after the amount of natural fluid flow has been detected.

Abstract: The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein.

Abstract: Various hard hat fan systems are provided. In a certain embodiment, fan system includes an impact absorbing layer with a channel that defines a recessed surface which extends into the impact absorbing layer away from an inner surface of a shell of a hard hat. Together, the inner surface of the shell and the recessed surface define a duct configured to provide fluid communication between an inlet of the channel and an air vent positioned along the channel. In another embodiment, fan system includes a mounting bracket with first and second cam levers which may be actuated into a locked position, and first and second channels. When in the locked position, the first and second cam levers bias the edges of a mounting ridge of the shell against the first and second channels of the mounting bracket such that the mounting bracket is retained on the shell.

Abstract: The present disclosure various apparatuses, and systems for 3D printing. The present disclosure provides three-dimensional (3D) printing methods, apparatuses, software, and systems for a step and repeat energy irradiation process; controlling material characteristics and/or deformation of the 3D object; reducing deformation in a printed 3D object; and planarizing a material bed including usage of a non-contact material removal mechanism.

Abstract: A nozzle segment includes an inner band, an outer band, and at least one nozzle vane extending between the inner and outer bands. The outer band includes a hook that extends radially outwardly from an outer surface. The hook is oriented to couple to a support within different first and second turbine engines. The hook extends circumferentially across the outer surface and includes slots defined therein. A first slot includes a first circumferential load surface, and a second slot includes a second circumferential load surface. When the nozzle segment is coupled within the first turbine engine, the first circumferential load surface engages an anti-rotation element while the second circumferential load surface does not engage an anti-rotation element. When the nozzle segment is coupled within the second turbine engine, the second circumferential load surface engages an anti-rotation element while the first circumferential load surface does not engage an anti-rotation element.

Abstract: A carbonated beverage maker includes a water reservoir, a carbon dioxide creation chamber, and a carbonation chamber. The water reservoir holds ice water and has a first impeller and a shroud surrounding the first impeller. The carbon dioxide creation chamber contains chemical elements and receives warm water. The chemical elements react with each other to create carbon dioxide when the warm water is introduced to the carbon dioxide creation chamber. The carbonation chamber is connected to the water reservoir and the carbon dioxide creation chamber. The carbonation chamber has a second impeller that includes a stem portion and blades. The stem portion and the blades define conduits therein. The blades create a low pressure region in a lower portion of the carbonation chamber such that carbon dioxide from the carbon dioxide creation chamber flows through the conduits to the low pressure region.

Abstract: A reconfigurable apparatus used to store removable vehicular doors, roofs, roof components and hitch accessories. A rolling frame supports pivoting door storage arms, removable roof storage framework components and tubes for storage of hitch accessories. Components can be reconfigured to allow for compact storage and/or vehicular transportation of the apparatus itself.

Abstract: An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.

Abstract: An example of a flow cell includes a substrate and a pattern of two different silanes on at least a portion of a surface of the substrate. A first polymer is attached to a first of the two different silanes and a second polymer is attached to a second of the two different silanes. The first and second polymers respectively include a first functional group and a second functional group of a functional group pair, the functional group pair being selected from the group consisting of an activated ester functional group and an azide functional group, a tetrazine functional group and an activated ester functional group, and a tetrazine functional group and an azide functional group. A first primer set is grafted to the first polymer and a second primer set is grafted to the second polymer. The first and second primer sets are different.

Abstract: An example of a resin composition includes an epoxy resin matrix, a free radical photoinitiator selected from the group consisting of 2-ethyl-9,10-dimethoxyanthracene, 2,2-dimethoxy-2-phenylacetophenone, 2-ethoxy-2-phenylacetophenone, and a phosphine oxide, and a photoacid generator. When cured, the resin composition has low or no autofluorescence when exposed to blue excitation wavelengths ranging from about 380 nm to about 480 nm or green excitation wavelengths ranging from about 510 nm to about 560 nm.

Abstract: A method for tuning one or more sensor devices is provided, wherein each sensor device comprises one or more proof masses configured to move in response to an external stimulus of interest, and the one or more proof masses are also susceptible to move in response to one or more stimuli other than the external stimulus of interest. Each sensor device also comprises one or more pick-off mechanisms respectively associated with each of the one or more proof masses. The one or more pick-off mechanisms is proportionally responsive to a motion of the sensor device. The method for tuning includes adjusting gain of one or more of the pick-off mechanisms to reduce an output of each sensor device when the one or more proof masses move in response to the one or more stimuli other than the external stimulus of interest.

Abstract: Described herein are heterocyclic azide-containing monomer units, copolymers comprising such heterocyclic azide-containing monomer units, substrate-bound copolymers, and oligonucleotide-bound copolymers, methods for making such copolymers and reacting them with a substrate and/or oligonucleotide, and methods of using such copolymers for immobilization of oligonucleotides to a substrate, for example for use in DNA sequencing or other diagnostic applications.