Abstract: Disclosed herein are compositions and methods for delivering compositions to a subject in need of treatment for epilepsy. The disclosed compositions are orally delivered. Further disclosed are kits comprising the disclosed compositions as part of a method of delivering cannabidiol and CBD-containing compositions to subjects in need of treatment for epilepsy.

Abstract: Catalyst systems for olefin polymerization include a metal-ligand complex of a general formula (I). The metal-ligand complex of formula (I) is a transition metal complex of titanium, zirconium, or hafnium, in which the transition metal is coordinated with a biaryl phenoxy ligand structure. Olefin polymerization processes include contacting ethylene and optionally one or more (C3-C12) alpha-olefins in the presence of the catalyst system to produce an ethylene-based polymer or copolymer.

Abstract: Processes for polymerizing polyolefins include contacting ethylene and optionally one or more (C3-C12)?-olefin in the presence of a catalyst system, wherein the catalyst system comprises a metal-ligand complex having a structure according to formula (I).

Abstract: An embodiment is directed to a touch bar exit device for use on an exit door. The touch bar exit device include a touch bar and a link bar which moves as the touch bar is depressed. A return mechanism is mounted on the link bar. A damper mechanism is mounted on the link bar. The damper mechanism limits the travel of the link bar and the touch bar to dampen the sound of the touch bar exit device when the touch bar is depressed.

Abstract: An adjustable mounting assembly for an outdoor unit of an air conditioning unit is disclosed. In some embodiments, the outdoor unit on the adjustable mounting assembly may be capable of moving among multiple height positions, for example, from a higher loading position to a lower installed position. For example, in some embodiments, the adjustable mounting assembly may include a counterbalancing mechanism to facilitate the position movement of the outdoor unit. In some other embodiments, the position movement of the outdoor unit may be achieved by folding and/or unfolding of a scissor lifting mechanism.

Abstract: A lock mechanism having a bolt movable between a thrown position and a retracted position, and a deadbolt assembly includes a sliding deadbolt configured to slide between a locked position in which the sliding deadbolt inhibits retraction of the bolt and an unlocked position. The sliding deadbolt includes a first anti-thrust cam configured to restrain the sliding deadbolt in the locked position, and a release driver arranged such that, when driven, the release driver releases the first anti-thrust cam from restraining the sliding deadbolt in the locked position and slides the deadbolt to the unlocked position.

Abstract: A duct includes a rigid air-permeable tube of composite material. The duct also includes a layer of insulation coupled to an exterior surface of the rigid air-permeable tube. The duct further includes a non-rigid insulation layer in contact with the layer of insulation. The non-rigid insulation layer forms an air-impermeable duct wall.

Abstract: A flow-through electrochemical detection system determines if a target nucleic acid polymer is present in a sample. This system contains, at a minimum, an assay reaction chamber that contains a porous working electrode to which target nucleic acid polymer capturing molecules are bound. As a sample passes through the working electrode, any target nucleic acid polymer present in the sample binds to the target nucleic acid polymer capturing molecules. After the sample passes through the flow-through electrochemical detection system, target nucleic acid polymer detectors are placed inside the assay reaction chamber and bind to any target nucleic acid polymer present. The target nucleic acid polymer detectors contain a means for generating an electric current when exposed to a chemical or an enzyme. A potentiostat connected to the working electrode measures the generated current, thereby detecting the presence and quantity of the target nucleic acid polymer in the sample.

Abstract: Display assemblies and related systems and methods for mounting are provided. A mounting structure includes a central airflow pathway for a first dedicated flow of ambient air with electronic equipment located along the same. One or more side assemblies are attached to the mounting structure and include a cover, a display layer located rearward of the cover, an illumination device for illuminating at least the display layer when operated, and a side assembly open loop airflow pathway for a second dedicated flow of the ambient air. When operated, the electronic equipment provides functionality other than operation of the one or more side assemblies. The central airflow pathway and the side assembly open loop airflow pathway of each of the one or more side assemblies are fluidly separated from one another.

Abstract: The invention relates to oxopyrimidinyl-methyl-benzamide derivatives, for example in a pharmaceutically acceptable salt form or crystal form, pharmaceutical compositions comprising the derivatives, and their medical use, in particular for use in the treatment of ?1-antitrypsin deficiency (A1AD or AATD).

Abstract: A droplet detection system includes a sensing channel, such as a microfluidic channel, configured to receive a flow of fluid that may contain one or more liquid droplets dispersed in the fluid. The cross-sectional area of the sensing channel maybe configured to allow droplets of a predetermined size to flow through the channel one at a time. A light source, a light aperture, and a light detector are positioned outside the sensing channel, which use light in a selected frequency band that has a substantially different absorbance for the liquid compared to the fluid. Liquid droplets may be detected and characterized using a signal from the light detector.

Abstract: This disclosure relates to GLP-1 agonists of Formula (I), including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

Abstract: A target material supply apparatus includes: first and second fluid flow components (1122, 1126) that define an axial flow path when joined together, in which the axial flow path is between a source of target material fluid and a nozzle supply apparatus; and a coupling apparatus configured to seal the joint between the first and second fluid flow components. The coupling apparatus includes a gasket (1105) having an annular shape defining an inner opening that is a part of the axial flow path when seated and sealed. When the gasket is seated between the first and second fluid flow components to thereby seal the joint formed by attaching the first and second fluid flow components, pressure applied to the gasket from target material fluid traversing the gasket inner opening along the axial flow path improves the hermetic function of the seal at the joint. Optionally, a functional insert like e.g. a flow restrictor (1160) can be seated in the gasket.

Abstract: A compressor has: a rotor and a shroud having a internal and external sides and an air outlet; an annular case mounted to the external side and enclosing a plenum, the annular case having inner and outer sides and defining an aperture; a valve mounted to the annular case at the aperture and having: a support secured to the annular case and defining a seat surrounding a bleed passage, the seat located on the outer side, the support defining a guiding aperture, and a valve member having a head and a stem slidably received within the guiding aperture, the valve member having a closed position and an open position, the head abutting the valve seat in the closed position and offset from the valve seat in the open position; and an actuator engaged to the valve member for moving the valve member between the closed position and the open position.

Abstract: Adjustable focal length eyewear (11) comprising two lenses (21, 22) that are mounted to a frame (14, 15, 16) for supporting the lenses (21, 22) in front of a user's eyes. At least one of the lenses (21, 22) is a variable focal length lens of the kind comprising two superposed lens elements (31, 41) having cooperating optical surfaces that are shaped such that the focal length of the variable focal length lens (21, 22) is variable according to the relative lateral disposition of the lens elements (31, 41). One of the lens elements (31) is fixedly mounted to the frame (14, 15, 16) and the other lens element (41) is movable manually relative to the fixed lens element (31) for varying the focal length of the variable focal length lens (21, 22).

Abstract: A clip assembly allows users to adjust the position at which the clip is mounted, allows for variance in mounting positions and styles, provides adjustability to allow a varying width of belts or webbing, and has cloth gripping abilities. The clip assembly can include a wire clip that is adjustably attached to a mounting base. The wire clip can, for example, be mounted facing upward, relative to the mounting base, downward, relative to the mounting base, or may adjustably slide to a desired position relative to the mounting base. A spacer may be provided that can adjust a size of an opening of the wire clip. The spacer may also provide a fabric catch member for helping keep the clip assembly in a desired position.

Abstract: A storage platform (100) improves data flow when modifying mirrored volumes. A backup storage component (120 A) that receives a service request keeps a copy of change data when redirecting the service request to a primary storage component (120B) that owns the volume that the service request targets. The primary storage (120B) component does not need to return the change data to the backup storage component (120A) when the primary storage component (120B) instructs the backup storage component (120 A) to apply the modification request to the backup copy of the volume.

Abstract: The validity of a mail item containing a monetary solicitation is determined. An image is received of the mail item and the image is analyzed to identify a plurality of data fields within the mail item. The validity or invalidity of the data within each of the plurality of identified data fields is then established, and a user-interactive image overlay is generated for the image of the mail item that includes a validity indicator for each of the plurality of identified data fields. The validity indicator is representative of the validity or invalidity of the data within each of the identified plurality of data fields. The user-interactive image overlay is sent to a user device to display the image of the mail item.

Abstract: A light detection and ranging (LIDAR) sensor system for a vehicle can include: a light source configured to output a beam; a photonics integrated circuit (PIC) including a semiconductor die, the semiconductor die including a substrate having two or more semiconductor stacks respectively associated with two or more semiconductor devices formed on the substrate, the two or more semiconductor devices respectively configured to receive the beam from the light source and modify one or more features of the beam; a transmitter configured to receive the beam from the semiconductor die; and one or more optics configured to receive the beam from the transmitter and emit the beam towards an object.

Abstract: A refrigerator appliance or ice making assembly may include an ice mold, a heat exchanger, a lifter arm, and a cam shaft. The ice mold may define a mold cavity for receiving water. The heat exchanger may be in thermal communication with the ice mold to freeze the water and form one or more ice cubes therein. The lifter arm may be disposed below the ice mold and movable relative to the mold cavity along a channel path between a lowered position and a raised position to raise ice cubes within the mold cavity. The cam shaft may include a rotating cam lobe slidably engaged with the lifter arm to direct the lifter arm between the lowered position and the raised position. The cam shaft may be rotatable about a cam axis horizontally offset from the channel path.