Abstract: An implantable neurostimulation device includes a system for determining at least one physiological and/or at least one biological parameter. The device is configured to derive a health status based at least in part on the at least one parameter. The system includes at least one element or shares at least one element associated with a neurostimulation therapy for determining the at least one parameter. Further aspects relate to a method carried out by such a device and a computer program.

Abstract: A pacemaker comprises a processing unit, a detector and a pacing signal generator, all electrically interconnected, the detector determines patient activity signals and provides the activity signals to the processing unit, the processing unit determines a pacing rate based on the currently received activity signals and on a gain value in an adaption or stabilized mode, the processing unit produces a pace control signal based on the determined pacing rate and provides it to the pacing signal generator, in the adaption mode the processing unit adapts the gain value to the specific patient, the processing unit stays in the adaption mode as long as a stability criterion is not met and transitions in the stabilized mode if a stability criterion is met, wherein in the stabilized mode the processing unit uses a locked gain value determined based on the most recently adapted gain values for determining the pacing rate.

Abstract: A system and method for neurostimulation of a patient's body includes a device to provide a unique combination of multiphase therapy modes that minimize the recruitment of large diameter nerve fibers and provides distributed neuron recruiting compounding effect thus reducing paresthesia. The system includes a plurality of Z electrodes. For the number of the plurality of electrodes, Z?3 applies. The delivers, via each electrode of a group of N electrodes (N?Z and if Z=3 then N=Z), a set of electric pulses including one therapeutic electric pulse having an amplitude I1, I2, . . . . IN and a number of (N?1) charge balancing electric pulses during one cycle. The charge balancing electric pulses each have a polarity being opposite a polarity of the therapeutic electric pulse. Each therapeutic electric pulse and each charge balancing electric pulse have a non-rectangular shape.

Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.

Abstract: A medical device for a patient's body includes an accelerometer unit and a processor which are electrically interconnected. The patient's body has two orthogonal axes (YP, ZP). The first orthogonal axis (YP) is given by the craniocaudal or similar axis of the patient's body and the second orthogonal axis (ZP) is given by the dorsoventral or similar axis of the patient's body. The accelerometer unit is configured to determine at least 2-dimensional acceleration data (YD-data, ZD-data) over time along the first orthogonal axis (YP) and the second orthogonal axis (ZP). There is also a respective method for determining the number of steps made by a patient using a medical device, a computer program product and a computer readable data carrier.

Abstract: A device used for neurostimulation includes a plurality of electrodes. In order to improve therapeutic efficacy when using a group of N electrodes equal to or larger than 3, the device is configured to deliver a number of N+1 electrical phases during one cycle via the electrodes such that during N electrical phases of the cycle each electrode of the group delivers alternating a therapeutic electric phase and a number of N?1 charge balancing electric phases. One electrode of the group delivers its specific therapeutic electric phase and the other electrodes of the group deliver a charge balancing phase having an opposite polarity of the therapeutic electric phase delivered, and such that during an additional electrical phase each electrode of the plurality of electrodes delivers an electrical phase with an amplitude that establishes charge neutrality for residual charge on each respective electrode based on phases of the N other electrical.

Abstract: An implantable cardiac pacemaker, wherein the pacemaker is configured to apply pacing pulses to the heart of a person during operation of the pacemaker, and wherein the pacemaker comprises a motion detection system that comprises a first module and a second module. The first module is configured to continuously run during operation of the pacemaker. The second module is configured to receive a trigger signal to change from an idle state to an active state or to receive a further trigger signal to change from an active state to an idle state. An energy consumption per time unit of the second module in the active state is larger than in the idle state. When the second module is in its active state, the second module is configured to execute a rate adaptation algorithm that adapts a rate of the pacing pulses to meet a metabolic demand of the person.

Abstract: The present invention relates to a system for remote patient monitoring. The system comprises at least one medical device, a patient remote device, a remote monitoring server device (RMS), and a health care professional (HCP) remote device. The at least one medical device is configured to automatically collect physiological data of a patient and transmit the collected physiological data of the patient to the RMS via the patient remote device. The RMS is configured to interface with the HCP remote device via a healthcare professional interface comprising a web-based portal and/or an app-based portal to allow a health care professional to access the collected physiological data of the patient on the RMS. In this way, it is possible to provide continuous remote monitoring of physiological data from a medical implant with no patient interaction required. The monitoring data is available to physicians via web-based and/or app-based user portal on-demand. The RMS may provide frequent (e.g.

Abstract: A system includes at least one medical device, a remote monitoring server (RMS), at least one patient remote device (PR) and at least one health care professional (HCP) remote device (CP). The system is configured such that one CP establishes a communication session connecting the one CP via the RMS and the PR with the chosen medical device by establishing a first bidirectional communication connection of the one CP and the RMS, triggering the RMS to establish a second bidirectional communication connection of the RMS and the PR corresponding to the chosen medical device and to establish a third bidirectional communication connection of the PR and the chosen medical device. The system is configured to provide real-time remote programming and/or interrogation of the chosen medical device using the one CP via the RMS and the corresponding PR, and to maintain continuous communication connections.

Abstract: An intra-body network system, comprises a first implantable medical device comprising a first communication circuitry and a second implantable medical device comprising a second communication circuitry. The first and second communication circuitries are configured to establish, in an implanted state of the first and second implantable medical devices, a communication for transmitting a communication signal from the first implantable medical device to the second implantable medical device and from the second implantable medical device to the first implantable medical device.

Abstract: A lead anchor for neuromodulation includes a solid anchor block having at least one opening and a lumen. The opening is connected with the lumen and has a longitudinal axis. The lumen is configured to receive a portion of the neuromodulation lead. An anchor body at least partially covers the anchor block. A fixing element has a fastening portion and a head portion. To achieve a lead anchor that is more robust against axially acting forces, so that primarily a slippage of the lead or a slippage of the lead anchor can be prevented, the fastening portion is configured to be inserted along the axis into the opening to fix the portion of the neuromodulation lead. The head portion includes at least one first stop feature having a dimension in a radial direction with respect to the axis that is greater than a diameter of the opening.

Abstract: A method programs an implantable medical device to configure the implantable medical device for stimulating neural tissue by at least one electrode. The method includes: performing, by the implantable medical device, an evoked compound action potential (eCAP) threshold search by stimulating the neural tissue with test stimulation pulses; determining, based on the eCAP threshold search, an eCAP threshold amplitude and a coupling factor that is indicative of a coupling between the at least one electrode and the neural tissue; and generating a first set of stimulation parameters containing at least a stimulation amplitude that is determined in dependence on the eCAP threshold amplitude and the coupling factor.

Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.

Abstract: A device for neurostimulation has a number N of electrodes. N is equal to or larger than 3. The device is configured to deliver via each electrode therapeutic electric phases of amplitudes I1, I2, . . . IN, with a frequency f and after each therapeutic electric phase a number of N?1 charge balancing electric phases. The charge balancing electric phases of the respective electrode each have a polarity that is opposite the polarity of the preceding therapeutic electric phase of the respective electrode. The device is configured to return for each electrode the current of each therapeutic electric phase in the other N?1 electrodes.

Abstract: A method for estimating an offset between a first group and a second group of contacts with respect to a longitudinal direction. Each group of contacts includes a plurality of electrodes arranged along a surface of a body of a lead. The method includes the steps of: (a) Selecting a number of electrode pairs, each electrode pair including an electrode of the first contact group and an electrode of the second contact group, and measuring the impedances between the electrodes of each selected electrode pair; (b) pre-conditioning the measured impedances for attenuating unwanted noise to generate pre-conditioned impedances, and (c) determining the lead offset using the pre-conditioned impedances.

Abstract: An adapter system connects to implantable electrode leads. The adapter system has the pulse generator configured to generate electrical stimulation pulses and has a first connector member. The adapter has a housing containing two receptacles. Each receptacle receives an end portion of an electrode lead to establish an electrical connection between the adapter and the electrode lead. The adapter contains a second connector member configured to engage with the first connector member to establish a mechanical connection between the housing and the pulse generator and an electrical connection between the pulse generator and the electrode lead. A test cable electrically connects the pulse generator to the electrode leads for testing the electrode leads. The test cable contains a first connector member configured to engage with the second connector member to establish an electrical connection. The test cable contains a second connector member configured to engage with the first connector member.

Abstract: A medical electrode device for implantation comprises a carrier formed from an electrically insulating material and defining a surface extending along a plane of extension, and at least one electrode arranged on the carrier for emitting an electrical stimulation signal and/or receiving an electrical sense signal. The at least one electrode comprises first and section wall sections. Said first wall section, in a cross-section along a cross-sectional plane perpendicular to said plane of extension, extends straight along a perpendicular direction with respect to said plane of extension or at an oblique angle with respect to said perpendicular direction, the first wall section in contact with the carrier electrically insulating material. Said second wall section, in said cross-section along said cross-sectional plane perpendicular to said plane of extension, adjoins said first wall section and is curved, the second wall section not in contact with the carrier electrically insulating material.

Abstract: A method programs an implantable medical device to configure the implantable medical device for stimulating neural tissue by at least one electrode. The method includes: performing, by the implantable medical device, an evoked compound action potential (eCAP) threshold search by stimulating the neural tissue with test stimulation pulses; determining, based on the eCAP threshold search, an eCAP threshold amplitude and a coupling factor that is indicative of a coupling between the at least one electrode and the neural tissue; and generating a first set of stimulation parameters containing at least a stimulation amplitude that is determined in dependence on the eCAP threshold amplitude and the coupling factor.

Abstract: A method programs an implantable medical device to configure the implantable medical device for stimulating neural tissue by at least one electrode. The method includes: performing, by the implantable medical device, an evoked compound action potential (eCAP) threshold search by stimulating the neural tissue with test stimulation pulses; determining, based on the eCAP threshold search, an eCAP threshold amplitude and a coupling factor that is indicative of a coupling between the at least one electrode and the neural tissue; and generating a first set of stimulation parameters containing at least a stimulation amplitude that is determined in dependence on the eCAP threshold amplitude and the coupling factor.

Abstract: A medical device for electrical stimulation of a patient. A pulse generator generates current pulses for the electrical stimulation. An electrode lead with a plurality of electrode contacts delivers the pulses to tissue of the patient. The pulse generator repeatedly delivers a current pulse between two electrodes forming a first group and delivers a charge balancing current pulse after each current pulse between the electrodes of the first group. The respective current pulse is separated from the succeeding charge balancing current pulse by an inter pulse interval. The respective current pulse has an amplitude with the same absolute magnitude as the succeeding charge balancing current pulse, but is of opposite sign. The pulse generator delivers between each current pulse and the succeeding charge balancing current pulse a current pulse between two further electrodes forming a second group of electrode contacts of the plurality of electrode contacts.