Patents by Inventor Andrew Fleming

Andrew Fleming has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100132509
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Application
    Filed: February 4, 2010
    Publication date: June 3, 2010
    Applicant: PLACER DOME TECHNICAL SERVICES LTD.
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Patent number: 7704298
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: April 27, 2010
    Assignee: Placer Dome Technical Services Limited
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Publication number: 20100024603
    Abstract: The present invention is directed to a precious metal recovery process in which basic ferric sulphates and/or jarosites are controlled by a number of mechanisms, including control of the oxidation reaction conditions in the first autoclave compartment, hot curing of the autoclave discharge slurry, and/or contacting of the autoclave feed slurry with the hot cured discharge liquid.
    Type: Application
    Filed: October 13, 2009
    Publication date: February 4, 2010
    Applicant: PLACER DOME TECHNICAL SERVICES LTD.
    Inventors: Jinxing Ji, James A. King, Christopher Andrew Fleming, Cesare Giosue Ferron
  • Patent number: 7604783
    Abstract: The present invention is directed to a precious metal recovery process in which basic ferric sulphates and/or jarosites are controlled by a number of mechanisms, including control of the oxidation reaction conditions in the first autoclave compartment, hot curing of the autoclave discharge slurry, and/or contacting of the autoclave feed slurry with the hot cured discharge liquid.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: October 20, 2009
    Assignee: Placer Dome Technical Services Limited
    Inventors: James A. King, Jinxing Ji, Christopher Andrew Fleming, Cesare Giosue Ferron
  • Patent number: 7559974
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: July 14, 2009
    Assignee: Placer Dome Technical Services Ltd.
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Patent number: 7527952
    Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to IMPDH or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of IMPDH or close structural homologues of the active site binding pockets. This invention also relates to compounds and pharmaceutical compositions which are inhibitors of IMPDH.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 5, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Keith P. Wilson, Michael D. Sintchak, Mark Andrew Fleming, David M. Armistead
  • Patent number: 7216041
    Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to IMPDH or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of IMPDH or close structural homologues of the active site binding pockets. This invention also relates to compounds and pharmaceutical compositions which are inhibitors of IMPDH.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: May 8, 2007
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Keith P. Wilson, Michael D. Sintchak, Mark Andrew Fleming, David M. Armistead
  • Patent number: 7066983
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: June 27, 2006
    Assignee: Placer Dome Technical Services Limited
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Patent number: 7065452
    Abstract: The present invention relates to crystallized molecules and molecular complexes which comprise the active site binding pocket or the FKBP12/FK506 binding pocket of calcineurin or close structural homologues to either binding pocket. This invention also relates to a data storage material encoded with the corresponding structure coordinates of those crystallized molecules or molecular complexes. Such data storage material is capable of displaying such molecules and molecular complexes as a graphical three-dimensional representation on a computer screen. In addition, this invention relates to methods of using the structure coordinates of those molecules or molecular complexes to solve the structure of homologous proteins. This invention also relates to methods of using the structure coordinates to screen and design compounds that bind to calcineurin or homologues thereof.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: June 20, 2006
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: David M. Armistead, Matthew James Fitzgibbon, Mark Andrew Fleming, James P. Griffith, Eunice E. Kim, Joseph L. Kim, Michael D. Sintchak, John Allan Thomson, Keith P. Wilson
  • Publication number: 20040206207
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Application
    Filed: April 30, 2004
    Publication date: October 21, 2004
    Applicant: Placer Dome Technical Services Limited
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Publication number: 20040035252
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Application
    Filed: May 27, 2003
    Publication date: February 26, 2004
    Applicant: Placer Dome Technical Services Limited
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Patent number: 6660059
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: December 9, 2003
    Assignee: Placer Dome Technical Services Limited
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Publication number: 20030057807
    Abstract: A first impedance synthesizing arrangement is adapted to accept an input voltage and to provide a corresponding output current according to a predefined relationship between the input voltage and the output current. A second impedance synthesizing arrangement accepts an input current and provides an output voltage. The first and second impedance synthesizing arrangements may be utilized in the vibrational damping apparatus. When using a digital signal processor in the impedance synthesizing arrangement, it is preferable to develop an algorithm which can be used to ensure that the predefined relationship between the voltage and the current is as required.
    Type: Application
    Filed: November 18, 2002
    Publication date: March 27, 2003
    Inventors: Andrew Fleming, Sam Behrens, Reza Moheimani
  • Publication number: 20020092377
    Abstract: Processes are provided for recovering precious metals from refractory materials using thiosulfate lixiviants. The processes can employ lixiviants that include at most only small amounts of copper and/or ammonia and operate at a relatively low pH, reduction of polythionates, inert atmospheres to control polythionate production, and electrolytic solutions which provide relatively high rates of precious metal recovery.
    Type: Application
    Filed: May 11, 2001
    Publication date: July 18, 2002
    Inventors: Jinxing Ji, Christopher Andrew Fleming, Paul George West-Sells, Ralph Peter Hackl
  • Patent number: 6128582
    Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to IMPDH or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of IMPDH or close structural homologues of the active site binding pockets. This invention also relates to compounds and pharmaceutical compositions which are inhibitors of IMPDH.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: October 3, 2000
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Keith P. Wilson, Michael D. Sintchak, Mark Andrew Fleming, David M. Armistead
  • Patent number: 5978740
    Abstract: The present invention relates to crystallized molecules and molecular complexes which comprise the active site binding pocket or the FKBP12/FK506 binding pocket of calcineurin or close structural homologues to either binding pocket. This invention also relates to a data storage material encoded with the corresponding structure coordinates of those crystallized molecules or molecular complexes. Such data storage material is capable of displaying such molecules and molecular complexes as a graphical three-dimensional representation on a computer screen. In addition, this invention relates to methods of using the structure coordinates of those molecules or molecular complexes to solve the structure of homologous proteins. This invention also relates to methods of using the structure coordinates to screen and design compounds that bind to calcineurin or homologues thereof.
    Type: Grant
    Filed: August 9, 1995
    Date of Patent: November 2, 1999
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: David M. Armistead, Matthew James Fitzgibbon, Mark Andrew Fleming, James P. Griffith, Eunice E. Kim, Joseph L. Kim, Michael D. Sintchak, John Allan Thomson, Keith P. Wilson
  • Patent number: 5807421
    Abstract: A hydrometallurgical process for treating copper feed materials containing gold and/or silver by simultaneously leaching copper, gold and/or silver into an aqueous cyanide solution, extracting copper, gold and cyanide with anion exchange resin is provided.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: September 15, 1998
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Christopher Andrew Fleming, Walther Gustav Grot, John Anton Thorpe
  • Patent number: 5667557
    Abstract: A hydrometallurgical process for treating copper feed materials containing gold and/or silver by simultaneously leaching copper, gold and/or silver into an aqueous cyanide solution, recovering copper in metallic form by electrowinning and regenerating cyanide ions is provided, wherein high current efficiencies are achieved at high current densities and at low copper concentrations.
    Type: Grant
    Filed: September 26, 1995
    Date of Patent: September 16, 1997
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Christopher Andrew Fleming, Walther G. Grot, John Anton Thorpe
  • Patent number: 5535757
    Abstract: A combination of a bottom undergarment and a prophylactic includes a bottom undergarment, such as a panty, having a crotch area and an opening formed in the crotch area, a condom, a base to which the condom is fixed, and snaps on the base for snapping into receptacles on the undergarment, so that the prophylactic and base are removable after use and replaceable. A second condom of a type suitable for oral sex may be attached to the base plate, which plate is reversible.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: July 16, 1996
    Inventor: Andrew Fleming, Jr.