Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: A computer-implemented method for modifying server resources using a client-side proxy may include (1) intercepting, at a proxy, a server resource request that was sent from a client application on a client device and directed to a remote server, (2) determining, at the proxy, a modification for a server resource response based on the request, (3) applying, at the proxy, the modification to the server resource response, and (4) sending, from the proxy, the modified server resource response to the client application. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A key assembly for a keyboard may include a key cap that includes a touch sensor that is communicatively coupled to a control device. When the touch sensor senses a touch event, the touch sensor may send a touch signal to the control device, and when the touch sensor senses an absence of touch, the touch sensor may send a control signal to the control device. The key assembly may further include a switch that is communicatively coupled to the control device and that is movable between a pressed position and an un-pressed position. When the switch is in the pressed position, the switch may send a closed signal to the control device, and when the switch is in the un-pressed position, the switch may send an open signal to the control device. Various other apparatuses, systems, and methods are also disclosed.

Abstract: Systems, methods, and non-transitory computer readable media can determine a depth of rendering a user interface (UI) element organized as a tree structure including one or more elements, wherein each element of the one or more elements is associated with a customary rendering logic and an alternative rendering logic. Whether an element in the tree structure is at a boundary for rendering the UI element can be determined based on the depth of rendering the UI element. In response to determining that the element is at the boundary for rendering, the element can be rendered according to the alternative rendering logic associated with the element.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: System and method for enabling data transformation topologies to be transported and/or distributed within a network of devices. In one embodiment, the system comprises: a network apparatus which runs a computer program configured to: (i) generate a plurality mathematical processes to be applied; and (ii) create an instruction set comprising an ordered list of ones of the processes, and information identifying one or more data types to be utilized with each of the processes. The system further comprises a plurality of user devices which run a second computer program configured to: (i) receive access to the processes and the instruction set; and (iv) perform the mathematical processes in the order provided by the instruction set to arrive at transformed data.

Abstract: Systems, methods, and non-transitory computer readable media can determine a depth of rendering a user interface (UI) element organized as a tree structure including one or more elements, wherein each element of the one or more elements is associated with a customary rendering logic and an alternative rendering logic. Whether an element in the tree structure is at a boundary for rendering the UI element can be determined based on the depth of rendering the UI element. In response to determining that the element is at the boundary for rendering, the element can be rendered according to the alternative rendering logic associated with the element.

Abstract: System and method for data tracking. In one embodiment, a method of tracing at least one health-related data record representative of at least one health-related parameter of at least one user thereof within a network of devices is given. The method comprises receiving, at a network apparatus, the at least one health-related data record generated at a health monitoring device; generating first metadata comprising at least information identifying the health-monitoring device and the at least one user; providing the at least one health-related data record to an apparatus configured to perform a transformational operation thereon to generate at least one transformed data record; and generating second metadata comprising at least information identifying the apparatus and the transformational operation which was performed. The first and second metadata are stored as a single metadata file relating to the at least one transformed data record.

Abstract: The exemplary embodiments relate to misalignment correction devices and methods for mitigating misalignment of a piece of oilfield equipment in or proximate an RCD. A rounded shoulder appears on a first surface within or proximate the RCD, and a socket profile appears on a second surface within or proximate the RCD. The second surface is configured to abut the rounded shoulder. The rounded shoulder is configured to rotate within the socket profile. Further, a floating joint may be implemented into or proximate the RCD and combined with the foregoing rotation mitigation features.

Abstract: A monitoring device arranged to be fitted to a door, wherein the door includes an operating bar mounted on the door for angular movement about its axis and a handle which is connected to the operating bar by a pivotal connection; wherein the device comprises a body element and a cover element arranged to slide relative to the body element and the two elements having a closed configuration and an open configuration in which the cover element is extended relative to the body element thereby allowing the device to be fitted to a door; the body and cover elements being shaped so that when in the closed configuration a pocket is formed that substantially surrounds an operating bar and further wherein the cover element comprises a portion extending over a region of a handle of a door to which the device is fitted such that that handle is prevented from rotating relative to the door; and monitoring circuitry arranged to monitor the device.

Abstract: Apparatus and methods are provided for enabling a sensor device to receive and transmit updates effectively via one or more rules applied to a plurality of event records for transmission by an event management server. In one exemplary embodiment, the event management server manages the plurality of event records (such as records of deletions or updates to a user's profile or goals), via an event suppression application. The event suppression application ensures that event records are not redundantly provided to the sensor device and/or irrelevant records (such as those which no longer contain the most up-to-date information) are not provided to the sensor device. Hence, only the most relevant event records are provided and that those which are not relevant are ignored (not transmitted). In this manner, the sensor device may operate more efficiently to receive only the most relevant transmissions.

Abstract: A cell culture device comprising a microscale chamber dimensioned to maintain a cell under conditions that give rise to a value for at least one pharmacokinetic parameter in vitro that is comparable to a value for the same at least one pharmacokinetic parameter obtained with respect to the same type of cell in vivo, wherein the microscale chamber is configured for flow of culture medium, and wherein the at least one pharmacokinetic parameter is selected from tissue size ratio, tissue to blood volume ratio, drug residence time, flow rate, circulatory transit time, liquid residence time, and liquid to cell ratio.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: A transmission system (8) comprising at least one floating gear (14a, 16a, 18a) rotationally mounted upon a first shaft the system comprising a floating gear activation system for controlling torque transfer between the at least one floating gear (14a, 16a, 18a) and the first shaft (10), the gear activation system comprising a first device (28, 30) having a friction interface (28) for frictional engagement with a friction interface (30) disposed on a first side of the at least one floating gear (18a), and a second device (25, 26) having a locking interface (25) for an interpositional engagement with a locking interface (26) disposed on a second side, opposing the first side, of the at least one floating gear (18a), whereby the floating gear (18a) is rotationally coupleable to the first shaft (10) by the friction interface (28/30) and/or the locking interface (25/26).