Abstract: This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel size. Particles can be repeatedly dehydrated and rehydrated in accordance to their environment, allowing for the storage of particles in a non-solvent such as ethanol. Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid at shear stresses that are below a critical value. Upon reaching the critical shear stress, the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The rheological behavior of these slurries can be adjusted by changing the compaction processes such as centrifugation force to alter the yield-stress. The narrower distribution and reduced size of these particles allows for an increase in FRESH printing fidelity.

Abstract: A power distribution system for a vehicle includes a plurality of switching devices arranged in a circuit to selectively control power flow between a plurality of buses operating within a same voltage range. The power distribution system further includes a controller programmed to, in response to the switching devices being in a state to transfer power between the buses and a current flowing through one of the buses exceeding a predetermined current, operate the switching devices to isolate the buses.

Abstract: A screw element (100) for an extrusion machine is provided. The screw element (100) includes a first section (200) and a second section. The first section (200 has a first core (212) with a plurality of facets (214) connected to each other along splines (216). The facets (214) and splines (216) extend longitudinally along the screw element (100). The facets (214) and splines (216) can be helically-shaped. The first core (212) increases in diameter in a continuous manner along the direction of flow of material. The first and second sections (200, 300) include one or more helically-shaped flights (218,219) wrapped around the longitudinal axis of the screw element (100).

Abstract: The present invention relates to a hetero-transglycosylase protein having cellulose:xyloglucan endotransglucosylase (CXE) activity in addition to mixed-linkage beta-glucan:xyloglucan endotransglucosylase (MXE) activity. The protein may comprise the amino acid sequence of any one of SEQ ID NOs: 2, 6 and 8 or a functional fragment thereof; or an amino acid sequence having at least 60% sequence identity to any one of SEQ ID NO: 2, 6 and 8, or to SEQ ID NO: 2 from amino acid 22 to 280, to SEQ ID NO: 6 from amino acid 26 to 283, or to SEQ ID NO: 8 from amino acid 29 to 287. The invention furthermore relates to an isolated nucleic acid encoding the protein described herein, a chimeric gene comprising, inter alia, the nucleic acid described herein, a vector comprising said chimeric gene, a host cell comprising said vector or said chimeric gene and an according transgenic plant. Further disclosed herein in are a method of producing a transgenic plant and a method of improving properties of cellulosic material.

Abstract: The present invention relates to a hetero-transglycosylase protein having cellulose:xyloglucan endotransglucosylase (CXE) activity in addition to mixed-linkage beta-glucan:xyloglucan endotransglucosylase (MXE) activity. The protein may comprise the amino acid sequence of any one of SEQ ID NOs: 2, 6 and 8 or a functional fragment thereof; or an amino acid sequence having at least 60% sequence identity to any one of SEQ ID NO: 2, 6 and 8, or to SEQ ID NO: 2 from amino acid 22 to 280, to SEQ ID NO: 6 from amino acid 26 to 283, or to SEQ ID NO: 8 from amino acid 29 to 287. The invention furthermore relates to an isolated nucleic acid encoding the protein described herein, a chimeric gene comprising, inter alia, the nucleic acid described herein, a vector comprising said chimeric gene, a host cell comprising said vector or said chimeric gene and an according transgenic plant. Further disclosed herein in are a method of producing a transgenic plant and a method of improving properties of cellulosic material.

Abstract: A computer that includes at least one processor and memory. The processor of the computer can be programmed to execute instructions stored on the memory that include controlling, based on a temperature, which of a plurality of power sources of a vehicle battery are coupled to a starter circuit during a vehicle ignition event.

Abstract: A power distribution system for a vehicle includes a plurality of switching devices arranged in a circuit to selectively control power flow between a plurality of buses operating within a same voltage range. The power distribution system further includes a controller programmed to, in response to the switching devices being in a state to transfer power between the buses and a current flowing through one of the buses exceeding a predetermined current, operate the switching devices to isolate the buses.

Abstract: A power distribution system for a vehicle includes a switching circuit configured to selectively enable power flow between a first bus and a second bus operable within a common voltage range. The power distribution system further includes a controller programmed to, in response to power flow being inactive and a current flowing through the first bus exceeding a current threshold, operate the switching circuit to enable power flow from the second bus to the first bus.

Abstract: The invention provides a chemical entity of Formula (I) wherein R1, R2, R3, R4, X, and Y have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive treatments; modulating and treating disorders mediated by GlyT1 activity; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training; and treating other disorders, including pain and alcohol-dependence.

Abstract: A computer that includes at least one processor and memory. The processor of the computer can be programmed to execute instructions stored on the memory that include controlling, based on a temperature, which of a plurality of power sources of a vehicle battery are coupled to a starter circuit during a vehicle ignition event.

Abstract: The invention provides a chemical entity of Formula (I) wherein R1, R2, R3, R4, X, and Y have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive treatments; modulating and treating disorders mediated by GlyT1 activity; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training; and treating other disorders, including pain and alcohol-dependence.

Abstract: A screw element (100) for an extrusion machine is provided. The screw element (100) includes a first section (200) and a second section. The first section (200 has a first core (212) with a plurality of facets (214) connected to each other along splines (216). The facets (214) and splines (216) extend longitudinally along the screw element (100). The facets (214) and splines (216) can be helically-shaped. The first core (212) increases in diameter in a continuous manner along the direction of flow of material. The first and second sections (200, 300) include one or more helically-shaped flights (218,219) wrapped around the longitudinal axis of the screw element (100).

Abstract: The invention provides a chemical entity of Formula (I), wherein R1, R2, R3, R4, R5 and X have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive treatments; modulating and treating disorders mediated by GlyT1 activity; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training; and treating other disorders, including pain and alcohol-dependence.

Abstract: The invention provides a chemical entity of Formula (I), wherein R1, R2, R3, R4, R5 and X have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive treatments; modulating and treating disorders mediated by GlyT1 activity; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training; and treating other disorders, including pain and alcohol-dependence.

Abstract: The present invention relates to a hetero-transglycosylase protein having cellulose:xyloglucan endotransglucosylase (CXE) activity in addition to mixed-linkage beta-glucan:xyloglucan endotransglucosylase (MXE) activity. The protein may comprise the amino acid sequence of any one of SEQ ID NOs: 2, 6 and 8 or a functional fragment thereof; or an amino acid sequence having at least 60% sequence identity to any one of SEQ ID NO: 2, 6 and 8, or to SEQ ID NO: 2 from amino acid 22 to 280, to SEQ ID NO: 6 from amino acid 26 to 283, or to SEQ ID NO: 8 from amino acid 29 to 287. The invention furthermore relates to an isolated nucleic acid encoding the protein described herein, a chimeric gene comprising, inter alia, the nucleic acid described herein, a vector comprising said chimeric gene, a host cell comprising said vector or said chimeric gene and an according transgenic plant. Further disclosed herein in are a method of producing a transgenic plant and a method of improving properties of cellulosic material.

Abstract: A rescue line apparatus is configured as a horizontal tether for being readily connected between a door and a portion of the door jamb or other entry location and extending a line as the user moves within the structure. The device allows the user to readily locate their way back for egressing the structure, and can be readily disengaged by the user, which activates a braking system that prevents unit “run-away”. A multi-attach anchor head couples the far end of the line to any desired structure, and has a beacon assembly which outputs a light pattern of sufficient brightness to be seen by the user when visually locating their attachment point within the structure. A multi-element visual indicator is configured for indicating line extension distance, and displaying tether line status. Many options promote safety and a fully cooperative environment.

Abstract: The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.

Abstract: A broadband computer system comprising a network, a client computer comprising a secure log-on means, a user interaction means, a display means, processing means and client data storage means, wherein applications used on the client computer are stored on the client data storage means; a server connected to the network comprising a secure log-on verification means and server data storage means, wherein the secure log-on means communicates with the secure log-on verification means across the network to authenticate a user and, after authentication, the processing means of the client computer provides a suite of applications for use by the user and wherein any user data required by the suite of applications is provided across the network by the server data storage means.

Abstract: A method and system for processing a polymer includes providing a molten polymer and processing the polymer into malleable components for delivery to a spirally wound conveying surface. Vibratory forces may be utilized to urge the components along the length of the conveying surface as they undergo crystallizing or drying or crystallizing and drying. Additional supplemental temperature control may be employed to affect crystallization and/or drying of the components along the conveying surface.

Abstract: This invention relates to compounds that bind to intracellular receptors and/or modulate activity of intracellular receptors, and to methods for making and using such compounds.