Patents by Inventor Andrew Lake

Andrew Lake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR CONTROLLING DIGITAL CINEMATIC CONTENT BASED ON EMOTIONAL STATE OF CHARACTERS
    Publication number: 20240134454
    Abstract: Provided is a system for controlling digital cinematic content based on emotional state of characters. A focus on one or more computer-controlled characters appearing in digital cinematic content is determined based on emotion indicators of a first user actively interacting with at least the one or more computer-controlled characters. A set of emotion indicators is inferred for each of the one or more computer-controlled characters based on one or more criteria and multifactor feedback loops are created. A story line of the digital cinematic content and behavioural characteristics of the one or more computer-controlled characters are controlled to achieve a target emotional arc of the first user based on the multifactor feedback loops.
    Type: Application
    Filed: November 1, 2023
    Publication date: April 25, 2024
    Inventors: Arvel CHAPPELL, III, Michael ZINK, Ha NGUYEN, Clayton MOSHER, Andrew VEEDER, Michael MARTINEZ, Shanshan SUN, Gary LAKE-SCHAAL
  • Anti-CCR8 antibodies and uses thereof
    Patent number: 11859000
    Abstract: The present disclosure is directed to antibodies or antigen-binding portions thereof that specifically bind human CCR8, polynucleotides and vectors encoding the same, and pharmaceutical compositions comprising the same. Some aspects of the disclosure are directed to methods of treating a disease or condition comprising administering the anti-CCR8 antibody to a subject in need thereof.
    Type: Grant
    Filed: January 6, 2021
    Date of Patent: January 2, 2024
    Assignee: Vaccinex Inc.
    Inventors: Pamela M. Holland, Andrew Lake, Austin Dulak, Ernest Smith, Maria Scrivens, Caroline Harvey, Renee Kirk, Leslie Balch, Sonia G. Das, Christopher Converse Wells
  • Anti-CD39 antibody compositions and methods
    Patent number: 11655303
    Abstract: The invention provides anti-CD39 antibody compositions and their use in treating cancer.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: May 23, 2023
    Assignee: Surface Oncology, Inc.
    Inventors: Scott Chappel, Andrew Lake, Michael Warren, Austin Dulak, Erik Devereaux, Pamela M. Holland, Tauqeer Zaidi, Matthew Rausch, Bianka Prinz, Nels P. Nielson, Sonia Das, Alison M. O'Neill
  • ANTIBODY MOLECULES TO CD73 AND USES THEREOF
    Publication number: 20230039109
    Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.
    Type: Application
    Filed: March 15, 2022
    Publication date: February 9, 2023
    Inventors: Bianka Prinz, Jerry M. Thomas, Ansgar Brock, Viviana Cremasco, Catherine Anne Sabatos-Peyton, Glenn Dranoff, Scott Chappel, Andrew Lake, Alison Paterson, Rachel W. O'Connor, Michael Warren, Pamela Holland, Kulandayan Kasi Subramanian, Helena Marie-Louise Fjaellskog, Dirksen Bussiere, Mikias Woldegiorgis, Wei Shu, John Delmas Venable, III, Michael Gladstone, Jonathan Hill, Christine Miller
  • ANTI-IL-27 ANTIBODIES AND USES THEREOF
    Publication number: 20230042258
    Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.
    Type: Application
    Filed: April 6, 2022
    Publication date: February 9, 2023
    Applicants: Surface Oncology, Inc., Adimab LLC
    Inventors: Jonathan HILL, Scott CHAPPEL, Michael GLADSTONE, Bianka PRINZ, Andrew LAKE, Christine MILLER, Kerry WHITE, Jing HUA, Pamela M. HOLLAND, Matthew RAUSCH, Devapregasan MOODLEY
  • METHODS OF TREATING CANCER WITH AN ANTI-CD39 ANTIBODY AND PEMBROLIZUMAB
    Publication number: 20230036592
    Abstract: The invention provides methods and uses of treating cancer with and IgG4 anti-CD39_229p antibody in combination with pembrolizumab, wherein the IgG4 anti-CD39_229p antibody is provided at particular doses and dosages.
    Type: Application
    Filed: June 2, 2022
    Publication date: February 2, 2023
    Inventors: Alison O'NEILL, Jou-Ku CHUNG, Robert ROSS, Andrew LAKE
  • Methods of Treating Cancer with an Anti-CD39 Antibody
    Publication number: 20220389115
    Abstract: The invention provides methods of treating cancer using an anti-CD39 antibody or fragment thereof as monotherapy or in combination with other therapies at particular dosages and frequencies.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 8, 2022
    Applicant: Surface Oncology, Inc.
    Inventors: Andrew Lake, Alison M. O'NEILL, Jou-Ku Chung, Robert Ross
  • Anti-CD39 Antibody Compositions and Methods
    Publication number: 20220372160
    Abstract: The invention provides anti-CD39 antibody compositions and their use in treating cancer. In some embodiments, an isolated anti-CD39 antibody is provided. Such an isolated anti-CD39 antibody binds to human CD39, wherein the antibody is optionally fully human or humanized. In some embodiments, the disclosure provides a method of enhancing, increasing and/or sustaining an anti-tumor immune response in a subject comprising administering the antibody or composition described herein to a subject having a tumor.
    Type: Application
    Filed: September 15, 2020
    Publication date: November 24, 2022
    Applicant: Surface Oncology, Inc.
    Inventors: Scott CHAPPEL, Andrew LAKE, Michael WARREN, Austin DULAK, Erik DEVEREAUX, Pamela M. HOLLAND, Tauqeer ZAIDI, Matthew RAUSCH, Bianka Prinz, Nels P. NIELSON, Sonia DAS, Alison M. O'Neill
  • ANTI-IL-27 ANTIBODIES AND USES THEREOF
    Publication number: 20220259299
    Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.
    Type: Application
    Filed: September 25, 2019
    Publication date: August 18, 2022
    Applicant: SURFACE ONCOLOGY, INC.
    Inventors: Jonathan HILL, Scott CHAPPEL, Michael GLADSTONE, Bianka PRINZ, Andrew LAKE, Christine MILLER, Kerry WHITE, Jing HUA, Pamela M. HOLLAND, Matthew RAUSCH, Devapregasan MOODLEY, Gege TAN
  • Anti-IL-27 antibodies and uses thereof
    Patent number: 11332524
    Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: May 17, 2022
    Assignees: Surface Oncology, Inc., Adimab LLC
    Inventors: Jonathan Hill, Scott Chappel, Michael Gladstone, Bianka Prinz, Andrew Lake, Christine Miller, Kerry White, Jing Hua, Pamela M. Holland, Matthew Rausch, Devapregasan Moodley
  • Antibody molecules to CD73 and uses thereof
    Patent number: 11312783
    Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: April 26, 2022
    Assignees: Novartis AG, SURFACE ONCOLOGY, INC.
    Inventors: Bianka Prinz, Jerry M. Thomas, Ansgar Brock, Scott Chappel, Andrew Lake, Alison Paterson, Rachel W. O'Connor, Michael Warren, Pamela Holland, Dirksen Bussiere, Mikias Woldegiorgis, Wei Shu, John Delmas Venable, Michael Gladstone, Jonathan Hill, Christine Miller
  • Method for the identification of immunotherapy-drug combinations using a network approach
    Patent number: 11186640
    Abstract: This invention relates to systems and methods for evaluating the differentiality of a set of discrete random variables between two or more conditions, such as a malignant condition responding to treatment regime and one that is not. It also provides for the identification and selection of drugs that act in coordinated manner to phenocopy a genetic network of a malignant condition that responds to at least an immune checkpoint blockade agent.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: November 30, 2021
    Assignee: THE UNIVERSITY OF WESTERN AUSTRALIA
    Inventors: Willem Joost Lesterhuis, Richard Andrew Lake, Anthony Bosco
  • Antibodies That Bind CD39 and Uses Thereof
    Publication number: 20210363268
    Abstract: The present disclosure relates to anti-CD39 antibodies, and antigen binding portions thereof and their use in treating cancer.
    Type: Application
    Filed: March 13, 2019
    Publication date: November 25, 2021
    Applicant: Surface Oncology, Inc.
    Inventors: Scott CHAPPEL, Andrew LAKE, Michael WARREN, Austin DULAK, Erik DEVEREAUX, Pamela M. HOLLAND, Tauqeer ZAIDI, Matthew RAUSCH, Bianka Prinz, Nels P. NIELSON, Sonia DAS
  • ANTI-CCR8 ANTIBODIES AND USES THEREOF
    Publication number: 20210238292
    Abstract: The present disclosure is directed to antibodies or antigen-binding portions thereof that specifically bind human CCR8, polynucleotides and vectors encoding the same, and pharmaceutical compositions comprising the same. Some aspects of the disclosure are directed to methods of treating a disease or condition comprising administering the anti-CCR8 antibody to a subject in need thereof.
    Type: Application
    Filed: January 6, 2021
    Publication date: August 5, 2021
    Applicant: Vaccinex, Inc.
    Inventors: Pamela M. HOLLAND, Andrew LAKE, Austin DULAK, Ernest SMITH, Maria SCRIVENS, Carrie HARVEY, Renee KIRK, Leslie BALCH, Sonia G. DAS, Christopher Converse WELLS
  • ANTIBODY MOLECULES TO CD73 AND USES THEREOF
    Publication number: 20210214459
    Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.
    Type: Application
    Filed: May 30, 2019
    Publication date: July 15, 2021
    Inventors: Ansgar Brock, Viviana Cremasco, Catherine Anne Sabatos-Peyton, Glenn Dranoff, Kulandayan Kasi Subramanian, Marie-Louise Fjaellskog, John Delmas Venable, III, Bianka Prinz, Jerry M. Thomas, Andrew Lake, Scott Chappel, Pamela Holland, Michael Warren, Alison Paterson, Rachel W. O'Connor, Michael Gladstone, Jonathan Hill, Christine Miller
  • Anti-CD39 Antibody Compositions and Methods
    Publication number: 20210095041
    Abstract: The invention provides anti-CD39 antibody compositions and their use in treating cancer.
    Type: Application
    Filed: September 15, 2020
    Publication date: April 1, 2021
    Applicant: Surface Oncology, Inc.
    Inventors: Scott CHAPPEL, Andrew LAKE, Michael WARREN, Austin DULAK, Erik DEVEREAUX, Pamela M. HOLLAND, Tauqeer ZAIDI, Matthew RAUSCH, Bianka Prinz, Nels P. NIELSON, Sonia DAS, Alison M. O'Neill
  • Antibodies That Bind CD39 and Uses Thereof
    Publication number: 20200399394
    Abstract: The present disclosure relates to anti-CD39 antibodies, and antigen binding portions thereof and their use in treating cancer.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 24, 2020
    Applicant: Surface Oncology, Inc.
    Inventors: Scott CHAPPEL, Andrew LAKE, Michael WARREN, Austin DULAK, Erik DEVEREAUX, Pamela M. HOLLAND, Tauqeer ZAIDI, Matthew RAUSCH, Bianka Prinz, Nels P. NIELSON, Sonia DAS
  • Antibodies that bind CD39 and uses thereof
    Patent number: 10793637
    Abstract: The present disclosure relates to anti-CD39 antibodies, and antigen binding portions thereof and their use in treating cancer.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: October 6, 2020
    Assignee: Surface Oncology, Inc.
    Inventors: Scott Chappel, Andrew Lake, Michael Warren, Austin Dulak, Erik Devereaux, Pamela M. Holland, Tauqeer Zaidi, Matthew Rausch, Bianka Prinz, Nels P. Nielson, Sonia Das
  • ANTI-CD47 ANTIBODIES AND METHODS OF USE
    Publication number: 20200291114
    Abstract: Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain hematological cancers and solid tumors.
    Type: Application
    Filed: January 16, 2020
    Publication date: September 17, 2020
    Inventors: Frank GROSVELD, Scott CHAPPEL, Jonathan HILL, Pamela M. HOLLAND, Andrew LAKE, Alison PATERSON
  • Antibodies That Bind CD39 and Uses Thereof
    Publication number: 20200277394
    Abstract: The present disclosure relates to anti-CD39 antibodies, and antigen binding portions thereof and their use in treating cancer.
    Type: Application
    Filed: May 13, 2020
    Publication date: September 3, 2020
    Applicant: Surface Oncology, Inc.
    Inventors: Scott CHAPPEL, Andrew LAKE, Michael WARREN, Austin DULAK, Erik DEVEREAUX, Pamela M. HOLLAND, Tauqeer ZAIDI, Matthew RAUSCH, Bianka Prinz, Nels P. NIELSON, Sonia DAS