Abstract: The present disclosure relates generally to methods of using modulators of interleukin-31 (IL-31) for treating, stabilizing, or lessening the severity or progression of pruritis.

Abstract: A device may include a housing with a plurality of top openings provided in a top portion of the housing and a plurality of bottom openings provided in a bottom portion of the housing. The device may include one or more internal components provided within the housing to provide a wireless service. The device may include a rotation extension connected to the bottom portion of the housing and configured to rotatably attach to a bracket that mounts the device to an object. The device may include a connector connected to the rotation extension and configured to receive a cable that provides communication signals to and from the device.

Abstract: The energy management system and method provide for the control of electrical loads within a group. The group of electrical loads are prioritized in terms of importance or criticality to remain electrically connected. Prioritization can be received as rankings input by the user or as a set of rankings generated by a learning-based artificial intelligence system. One or more energy-related goals are input, with the one or more energy-related goals including at least one energy-related parameter. The one or more energy-related goals may be received as input from the user through a user interface, using, for example, a sliding controller displayed to the user on the user interface. Energy consumption of each of the electrical loads in the group is monitored, and at least one lowest ranked electrical load is disconnected when the monitored energy consumption deviates from the one or more energy-related goals.

Abstract: Methods and systems are provided for foreign object debris monitoring in an environment with a dynamic debris field, such as an environment for operating an aircraft. The debris monitoring technique includes generating a light beam and dispersing it to create a virtual witness plate, which is a two-dimensional sheet of light that covers a detection area. The technique also include detecting scattered light from the virtual witness plate caused by debris passing through it. A debris event may be generated based on the scattered light, indicating the presence of debris in the detection area.

Abstract: A dosage form with a first portion and a second portion. The first portion can be an immediate release portion and can comprise a pain reliever, which can be naproxen or naproxen sodium. The second portion can be an extended release portion and can comprise pseudoephedrine or a pharmaceutically acceptable salt thereof and/or dextromethorphan or a pharmaceutically acceptable salt thereof. The dosage form can optionally comprise a stabilizing agent. The dosage form can be adapted to maintain a therapeutically effective amount of pain reliever, pseudoephedrine, or a pharmaceutically acceptable salt thereof, and/or dextromethorphan, or a pharmaceutically acceptable salt thereof, for at least eight hours.

Abstract: An electricity meter comprising an electrically-controlled electromechanical switch is disclosed. The electromechanical switch comprises a rotary actuator comprising a generally-cylindrical permanent magnet rotor having a central axis, a stator comprising a closed stator core and first and second opposite stator poles inwardly-projecting from the closed stator core towards the rotor and first and second coils wound around the first and second stator poles respectively. The electromechanical switch comprises a switch comprising at least one pair of first and second contacts wherein the first contact is movable. The electromechanical switch comprises mechanical linkage between the rotary actuator and the movable contact(s) configured such that rotation of the rotor from a first angular position to a second angular position causes the switch to be opened, and rotation from the second angular position to the first angular position causes the switch to be closed.

Abstract: A method and apparatus for treating a liquid using ultraviolet radiation. A thin flow of liquid in a supercritical flow is irradiated by at least one radiation source external to the thin flow. The flow may desirably have a Froude number greater than 3 and a velocity greater than 0.8 m/s. The apparatus for treating a liquid including may have a reservoir supplying liquid though a slot into an open channel to generate a thin flow of liquid having a supercritical flow along the channel with at least one radiation source external to the thin flow to irradiate the thin flow.

Abstract: A fluid delivery system for a dental cleaning appliance includes a nozzle for delivering a burst of working fluid to the teeth of a user, and a fluid conduit for conveying working fluid to the nozzle. A body of the nozzle defines a fluid chamber and a channel for conveying working fluid from the fluid chamber to a fluid outlet from the nozzle. The fluid chamber has a tangential inlet for receiving working fluid from the fluid conduit.

Abstract: Disclosed herein are methods, uses and compositions for the treatment or prophylaxis of cancer in a mammalian subject comprising administering to the subject an amount of an agent which targets an extracellular portion of KRT14 or its functional homolog or variant thereof resident on cancer cells or an agent which induces production of an antagonist of the extracellular portion of KRT14 or its functional homolog or variant on cancer cells. The present disclosure also extends to methods of monitoring and/or diagnosing cancer in a subject.

Abstract: Methods to determine the absence or presence of one or more cancer types in an animal are disclosed herein. In some embodiments, amounts of lipids in a sample (e.g., a bodily fluid or treatment thereof) from the animal are used with a predictive model to make the determination. The lipid amounts can be measured, in some instances, using a mass spectrometry system.

Abstract: This invention relates to a vehicle power coupling apparatus for a vehicle. The apparatus has a pickup coil arrangement for receiving an alternating magnetic field applied to the vehicle for generating power to operate the vehicle. The apparatus further has a shield for shielding a region including the pickup coil arrangement from an interior of the vehicle where a user of the vehicle may be present when the vehicle is in operation, and the shield includes at least one hole therein for providing access to one or more components of the vehicle for working on the one or more components. Additional aspects of the invention relate to receiving an alternating magnetic field and converting the alternating magnetic field into electrical power for recharging a vehicle and/or for providing motive power to the vehicle.

Abstract: An electromagnetic flow sensor for an electromagnetic flow meter (201) is disclosed. The sensor comprises a body (204) or frame, a flow passage (252) through the body or frame, a part of a magnetic circuit (248, 295) supported by the body or frame for applying a magnetic field across the flow passage, and at least first and second electrodes (298) supported by the body or frame, the at least first and second electrodes arranged to sense a voltage in response to a conductive fluid flowing through the flow passage. At least a portion of the body supporting the magnetic circuit part and the at least first and second electrodes is configured to be insertable into a flow tube (206) through a single aperture in the flow tube.

Abstract: A method and apparatus for treating a liquid using ultraviolet radiation. A thin flow of liquid in a supercritical flow is irradiated by at least one radiation source external to the thin flow. The flow may desirably have a Froude number greater than 3 and a velocity greater than 0.8 m/s. The apparatus for treating a liquid including may have a reservoir supplying liquid though a slot into an open channel to generate a thin flow of liquid having a supercritical flow along the channel with at least one radiation source external to the thin flow to irradiate the thin flow.

Abstract: According to the present invention an infusion pump is provided within an angler's live well. The infusion pump readily dispenses additives into the water that fills the live well, counteracting the debilitating effects of ammonia released by the live fish. Upon activation by the angler the pump dispenses a controlled volume of liquid additive quickly and conveniently into the live well. In one embodiment a hemispherical bulb pump dispenses fluid additive. A second embodiment utilizing an electric pump is also disclosed. In a third embodiment a gravity fed infusion pump is described.

Abstract: This invention relates to a wireless vehicle recharging apparatus for an energy storage element of a vehicle. The apparatus has at least one drive unit arrangement coupled to at least one drive coil arrangement disposed for generating a magnetic field extending from the drive coil arrangement, and includes a corresponding vehicle-mounted pickup coil arrangement coupled to a power conditioning circuit arrangement for receiving the extending magnetic field. The drive unit arrangement is operable to excite the drive coil arrangement at a fundamental frequency and the drive coil arrangement is implemented to be substantially devoid of ferromagnetic components for providing a path for the extending magnetic field. Additional aspects of the invention relate to vehicle power coupling apparatus including pickup coil arrangements.

Abstract: Described herein is a system and method of generating precise location information. Feature points of an image are received from a user device (e.g., mobile phone). Location information of the user device (e.g., GPS coordinates) and relative transform information from the user device are also received. An image anchor is identified based upon the received feature points, relative transform information, and the received location information. Precise location information of the identified image anchor is provided to the user device. The precise location information of the identified image anchor is based upon filtered feature points, location information and relative transform information received from a plurality of user devices over a period of time (e.g., hours, days, weeks, months). The precise location information of the identified image anchor is updated based upon the location information of the user device and the relative transform information received from the user device.

Abstract: The present disclosure relates generally to methods of treating human patients suffering from a liver disease or condition. The disclosure also provides diagnostic methods for determining the stage or status of the liver disease or condition and monitoring methods for assessing the effectiveness of a treatment, using serum protein, metabolites or bile acid markers.

Abstract: The present invention provides a method and apparatus for deterring pets or other animals from biting or chewing into medication containers. In some embodiments, the invention consists of two or more conductive metal sheets or strips in layers around the side of the container, which are wired to complete a circuit when pressed by the force of an animal's bite or touched by an animal's tongue. In some embodiments, the sheets or strips are spaced or held apart so that a normal human grip would not have sufficient force to complete the circuit. In some embodiments, the device slides onto the medication container with a friction fit, and is removable for use on future containers. In some embodiments, the circuit includes a battery-powered alarm to deter the animal. In other embodiments, the circuit delivers a mild electrical shock to the animal's mouth or tongue through the metal strips or sheets.

Abstract: A method for an ultrasonic time-of-flight flow meter (1) includes driving an ultrasonic transducer (2, 3) using a first waveform (V1(t)) for a first duration (?t1), the first waveform (V1(t)) configured to cause oscillation (21) of the ultrasonic transducer (2, 3). The method also includes driving the ultrasonic transducer (2, 3) using a second waveform (V2(t)) for a second duration (?t2). There is a discontinuity between the first waveform (V1(t)) and the second waveform (V2(t)). The second waveform (V2(t)) and the second duration (?t2) are configured to maintain a voltage (VT(t)) across the ultrasonic transducer (2, 3) within a predetermined range (VH, VL).