Abstract: A two-step method for activating a cellulosic feedstock is described. The feedstock is subjected to a first high temperature activation step at a temperature greater than 190° C. and a second activation step at a lower temperature under alkali conditions. Also described are methods and compositions for the enzymatic hydrolysis of activated cellulose using one or more cellulase enzymes, a surfactant and polyaspartic acid. Also described are products of the methods.

Abstract: The present invention is directed to new stable immediate release tablet and capsule formulations for the Janus Kinase 3 (JAK3) inhibitor 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one para-toluenesulfonate having structure

Abstract: A journal of operations persistently stores a collection of user and machine interactions with documents, concepts within documents, and relationships/mentions among such documents and concepts. A knowledge graph or other visual expression can be used to provide an interactive format for user interactions with this information, and to visually display the accumulated information in the journal of operations on user's device of choice. Such accumulations are often called aggregations or aggregates. Both human users and computer users such as automated recommendation engines, machine learning algorithms, and the like can interact with the journal of operations to facilitate computer-assisted discovery and organization of data around a topic of interest to the human user. The resulting journal of operations and aggregations of those operations such as a knowledge graph or other visual expression(s) also provides a useful medium for sharing knowledge with other users and collaborating on investigation of a topic.

Abstract: A process for making a packaged laundry detergent powder.

Abstract: Disclosed are systems and methods of detecting an impulse of energy given off by an injection device and determining a dosage of medicine based on the impulse. In one example, a module detects the vibrations given off by dialing a click-wheel on an autoinjector and determining the selected dosage of medicine based on the dialed dosage.

Abstract: A discriminator trained on labeled samples of speech can compute probabilities of voice properties. A speech synthesis generative neural network that takes in text and continuous scale values of voice properties is trained to synthesize speech audio that the discriminator will infer as matching the values of the input voice properties. Voice parameters can include speaker voice parameters, accents, and attitudes, among others. Training can be done by transfer learning from an existing neural speech synthesis model or such a model can be trained with a loss function that considers speech and parameter values. A graphical user interface can allow voice designers for products to synthesize speech with a desired voice or generate a speech synthesis engine with frozen voice parameters. A vector of parameters can be used for comparison to previously registered voices in databases such as ones for trademark registration.

Abstract: An apparatus for detecting a condition or authenticity of one or more electronic devices includes an enclosure having an antenna integrated therewithin, a fixture mounted within a hollow interior of the enclosure, the fixture being configured to receive the one or more electronic devices and connect one or more signals to each of the one or more electronic devices and a sensor and controller assembly connected to the antenna and configured to process a signature of an emission of a radiofrequency (RF) energy from of one or more electronic devices having the one or more signals connected thereto.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.

Abstract: Provided is a frangible munitions device optimized for a dome and cylinder that yields fragments having shapes corresponding to a predetermined embossment pattern upon explosive rupture. The embossment pattern includes a first set of inner regular hexagonal embossments formed into the dome and cylinder that are aligned with the axis of the cylinder, and a second set of outer pre-deformed hexagonal shapes that distort to produce regular hexagonal shapes after drawing into the cylinder wall. The second set of shapes are separated by sharp transition regions. The shapes are embossed in a repeated pattern around the hollow cylinder and the dome top. The dome yields a plurality of fragments having shapes corresponding to the first set of inner regular hexagonal embossments upon explosive rupture, while the cylinder yields a plurality of fragments having shapes corresponding to the second set of outer pre-deformed hexagonal embossments upon explosive rupture.

Abstract: Embodiments automate surfacing of underutilized development tool features, thereby enhancing the discoverability of subtools, commands, shortcuts, settings, visualizers, and other tool features. After spotting an inefficiency in the user's interaction with one or more tools, the feature surfacing functionality offers the user an interaction optimization suggestion. A mapping structure correlates detected interaction patterns with objectively better interaction optimizations. Several examples of mappings are discussed. The user can accept a suggestion, have the suggested optimization applied by an enhanced tool, and thereby reduce the number of user gestures utilized to accomplish a desired result, reduce the number of tools utilized, increase security, reduce risk of error, or get to the desired result faster, for example. Interaction optimizations also help the user stay focused, by reducing or avoiding departures from the user's current primary workflow.

Abstract: A two-step method for activating a cellulosic feedstock is described. The feedstock is subjected to a first high temperature activation step at a temperature greater than 190° C. and a second activation step at a lower temperature under alkali conditions. Also described are methods and compositions for the enzymatic hydrolysis of activated cellulose using one or more cellulase enzymes, a surfactant and polyaspartic acid. Also described are products of the methods.

Abstract: Disclosed are thickened organic liquid compositions comprising an organic liquid and a polymeric rheology modifier wherein the polymeric rheology modifier is obtainable by co-polymerizing at least two of a bicyclic (meth)acrylate ester, an alkyl (meth)acrylate, and an aromatic vinyl monomer. Also disclosed are thickened organic liquid dispersions with suspended solids and methods of stabilizing dispersions using polymeric rheology modifiers.

Abstract: A hand-held centripetal exercise devices are shown and disclosed. In one embodiment, the device includes an outer shell having a smooth outer surface. The outer shell defines an internal volume. The device additionally includes a single ball sized to be contained within the internal volume. The single ball having a predetermined mass.

Abstract: An administration system for delivery of a pharmaceutical composition to a patient has a delivery device configured to deliver a dose of the pharmaceutical composition to the patient and a notification device in communication with the delivery device. The notification device is configured to communicate information about a status of at least one property of the delivery device. The delivery device can be a wearable automatic injector configured to be worn on the patient's skin. The delivery device of the present disclosure may allow a user or the patient to view a status of a container. For example, the delivery device of the present disclosure may provide a simple and effective visual means of displaying fill confirmation and delivery confirmation.

Abstract: Provided herein are purified hemicellulose compositions, sweetener compositions including purified hemicellulose compositions, as well as methods for making the same. Also provided are uses of the compositions.

Abstract: An air conditioning pack of a cooling system includes an air cycle machine assembly, a cabin air compressor assembly, and a mixing duct. The air cycle machine assembly includes a compressor configured to receive an air stream that includes bleed air to generate a compressed air stream. The air cycle machine assembly utilizes a first portion of the compressed air stream to power the compressor. The cabin air compressor assembly receives a second portion of the compressed air stream, and utilizes the second portion to generate compressed ram air. The mixing duct receives the compressed ram air and allows the compressed ram air to mix with one or more of the air stream upstream of the compressor or the compressed air stream downstream of the compressor to generate a hybrid air stream that is used for cooling at least a portion of a vehicle.

Abstract: Embodiments automate surfacing of underutilized development tool features, thereby enhancing the discoverability of subtools, commands, shortcuts, settings, visualizers, and other tool features. After spotting an inefficiency in the user’s interaction with one or more tools, the feature surfacing functionality offers the user an interaction optimization suggestion. A mapping structure correlates detected interaction patterns with objectively better interaction optimizations. Several examples of mappings are discussed. The user can accept a suggestion, have the suggested optimization applied by an enhanced tool, and thereby reduce the number of user gestures utilized to accomplish a desired result, reduce the number of tools utilized, increase security, reduce risk of error, or get to the desired result faster, for example. Interaction optimizations also help the user stay focused, by reducing or avoiding departures from the user’s current primary workflow.

Abstract: A lifting system for a mobility device has a bracket fixed to the mobility device. A hoist connector is configured to removably connect to the bracket to provide lifting of the mobility device in use. One of the bracket and the hoist connector has a pin and the other of the bracket and the hoist connector comprises a clip, the pin having a head formation and a neck formation. The clip has an aperture configured to pass over the head formation in use and into engagement with the neck formation such that the clip is loosely held on the pin, and where the clip has a close fit with the head formation to prevent unintentional disengagement from the pin in use.

Abstract: A vehicle wash facility includes a bay extending between a pair of sidewalls and including at least one cleaning component. An upper level structure is located above the bay and supports a supporting component associated with the cleaning component above the at least one cleaning component. The upper level structure may be configured as a mezzanine structure that hangs from a ceiling of the car wash facility and is in the form of a grate. The upper level structure is stacked above the cleaning area, reducing the overall footprint and providing visibility through the sidewalls to the cleaning area. The upper level structure may be spaced form the sidewalls to define an open space in which cleaning components can move vertically. The cleaning components may be accessible through the upper level structure.

Abstract: A delivery device for delivering a medical fluid to a patient has a housing configured for receiving a container at least partially filled with the medical fluid. The delivery device further has a drive mechanism associated with the housing configured for delivering the medical fluid from the container to the patient in a dosing procedure. The delivery device further has a module configured for detecting at least one of a property of the dosing procedure and a property of the medical fluid. The module has at least one dose detection sensor configured for detecting an initiation, progression, and completion of the dosing procedure based on a position of a stopper within the container. The module further has at least one temperature sensor configured for measuring a temperature of the medical fluid within the container based on a temperature of the container.