Abstract: An FDM printer that provides five degree-of-freedom printing capabilities. In one embodiment, the FDM printer includes three transitional drive devices that allow a printer print head to be translationally moved in the X, Y and Z axes planes and a pair of rotationally drive devices that allow a workpiece platform to be rotated in the Y-axis plane and the combined X-axis and Z-axis planes. In this manner, the relative position between the print head and the workpiece platform allows the printer to print complex workpieces in a single continuous print, such as workpieces including large closed, hollow geometries, and without the need for providing support structures for overhangs and the like.

Abstract: A feed mechanism for feeding a filament into a print head assembly in an FDM printer. The feed mechanism includes a drive assembly that drives the filament into a reservoir where the reservoir is heated by a heater, where the filament is liquefied therein. A pump in the reservoir pumps the liquefied filament material out of the reservoir through an extrusion nozzle to a print head of the printer.

Abstract: A feed mechanism for feeding a filament through a print head assembly in an FDM printer. The feed mechanism includes a first oval-shaped track having a plurality track elements extending around the first track and a second oval-shaped track having a plurality of track elements extending around the second track, where the first and second tracks counter-rotate. A space is defined between the first and second tracks that receives the filament in a manner so that the track elements that are in the space contact the filament, where rotation of the first and second tracks in opposite directions causes the filament to be driven through the space and onto the print head.

Abstract: An FDM printer that provides five degree-of-freedom printing capabilities. In one embodiment, the FDM printer includes three transitional drive devices that allow a printer print head to be translationally moved in the X, Y and Z axes planes and a pair of rotationally drive devices that allow a workpiece platform to be rotated in the Y-axis plane and the combined X-axis and Z-axis planes. In this manner, the relative position between the print head and the workpiece platform allows the printer to print complex workpieces in a single continuous print, such as workpieces including large closed, hollow geometries, and without the need for providing support structures for overhangs and the like.

Abstract: A method including steps of communicatively coupling a first network device, such as a mobile phone, with a wireless transceiver, which may, in some embodiments, be integrated into a vehicle. The first network device may include specialized logic stored thereon. The method may include additional steps of receiving, by the first network device, a first beacon transmitted by the wireless transceiver and determining, by the logic of the first the network device, a value indicating a signal strength of the first beacon. In response to the value indicating the signal strength of the first beacon is greater than or equal to a first threshold, restricting, by the logic of the first network device, a predefined list of one or more functionalities of the first network device, wherein the one or more functionalities comprise a predefined list of functionalities of the first network device.

Abstract: A method including steps of receiving, by a cloud server, a predefined list of one or more functionalities to restrict, the predefined list generated via user input and communicatively coupling, by a wireless transceiver, with a first network device is disclosed. Additional steps include transmitting, by the wireless transceiver, a first message to the first network device, the first message configured to prompt a software application installed on the first network device to obtain a value indicating a strength of a detected magnetic field, wherein the magnetic field is generated by one or more magnets, and responsive to the value indicating the strength of the detected magnetic field is greater than or equal to a first threshold, restricting, by the software application, the predefined list of one or more functionalities of the first network device.

Abstract: A cracking furnace construction includes a firebox defining a chamber having a high emissivity thermal protective coating disposed on at least part of the refractory walls and/or on process tubes disposed within the chamber. The coating contains an inorganic adhesive for metal/alloy tubes or colloidal silica and/or colloidal alumina for refractory walls or ceramic tubes, a filler, and one or more emissivity agents. A method of coating the firebox chamber includes preparing the surface of the tubes/refractory walls, preparing the coating, and applying the coating to the surface.

Abstract: Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.

Abstract: A burner tip, and method of manufacture, has a support layer with an external surface exposed to combustion reactions and an unexposed internal surface defining at least one a passage therethrough to deliver fuel and combustion gasses, and a thermal protective layer disposed on at least part of the unexposed surface of the burner tip support layer. The thermal protective layer 22 has from about 5% to about 40% of an inorganic adhesive, from about 45% to about 92% of a filler, and from about 1% to about 20% of one or more emissivity agents.

Abstract: A cooling system for beverage dispense has a circuit 5 in which binary ice is circulated. A modular heat exchange unit 13 for a plurality of beverage lines 25,27,29,31,33 is connected to the circuit 5 for cooling beverage prior to dispense from a dispense tap 35 in a serving area such as a bar. The ice fraction in the binary ice provides a thermal store that can absorb heat without increasing the temperature of the binary ice and enables the system to respond quickly to changes in the cooling requirements in the circuit 5.

Abstract: Process and apparatus to form vinyl chloride monomer from ethylene dichloride in a cracking furnace, including a firebox chamber having a thermal protective layer disposed on refractory walls and/or process tubes disposed within the chamber, a quencher to form vinyl chloride monomer, and fractionator separate products. The thermal protective layer which contains an inorganic adhesive for metal/alloy tubes or colloidal silica and/or colloidal alumina for refractory walls or ceramic tubes, a filler, and one or more emissivity agents.

Abstract: Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.

Abstract: Lentivector constructs for expression of recombinant proteins, polypeptides or fragments thereof and methods of making the same are described. The lentivectors typically have a self-processing cleavage sequence between a first and second protein or polypeptide coding sequence allowing for expression of a functional protein or polypeptide under operative control of a single promoter and may further include an additional proteolytic cleavage sequence which provides a means to remove the self-processing cleavage sequence from the expressed protein or polypeptide. The vector constructs find utility in methods relating to enhanced production of biologically active proteins, such as immunoglobulins or fragments thereof in vitro and in vivo.

Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.

Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.

Abstract: A burner tip, and method of manufacture, has a support layer with an external surface and an internal surface defining at least one opening therethrough defining a passage therethrough to deliver fuel and combustion gasses, and a thermal protective layer disposed on at least one surface of the burner tip support layer. The thermal protective layer 22 has from about 5% to about 40% of an inorganic adhesive, from about 45% to about 92% of a filler, and from about 1% to about 20% of one or more emissivity agents.

Abstract: Process and apparatus to form vinyl chloride monomer from ethylene dichloride in a cracking furnace, including a firebox chamber having a thermal protective layer disposed on refractory walls and/or process tubes disposed within the chamber, a quencher to form vinyl chloride monomer, and fractionator separate products. The thermal protective layer which contains an inorganic adhesive for metal/alloy tubes or colloidal silica and/or colloidal alumina for refractory walls or ceramic tubes, a filler, and one or more emissivity agents.

Abstract: A tube shield, and method of manufacturing the tube shield, having a support structure with an external surface, an internal surface, and an edge, and a thermal protective layer on at least one surface of the shield support structure. The thermal protective layer is composed of a filler, one or more emissivity agent, and either an inorganic adhesive or a binder that is colloidal silica, colloidal alumina, or combinations thereof. A colorant, a surfactant, and/or a stabilizer may be incorporated into the thermal protective layer.

Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.

Abstract: Apparatus for mixing two fluids has separate supply lines for delivering the fluids to a mixing head. Flow rate of fluid in one supply line is monitored by arranging a pressure transducer to measure a pressure drop across an orifice in an orifice plate arranged in the supply line and a controller is responsive to the detected flow rate to control flow rate of fluid in the other supply line to achieve a desired flow ratio of both fluids at the mixing head for producing a mixed fluid having the correct proportions of both fluids. The fluids may be a concentrate syrup and a plain or carbonated water to produce a beverage.