Abstract: A method for associating published media with a subject includes receiving a cancerous biological specimen, sequencing it to obtain subject genomic data, identifying first and second alteration nomenclature matches to the subject genomic data in data extracted from first and second published media, applying a hierarchical rule set to the media based on the alteration nomenclature matches and one or more evidence metrics, the hierarchical rule set resulting in reporting a first treatment in the first medium and excluding reporting of a second treatment in the second medium despite a match between the second medium and subject disease states, identifying a reporting template based on the subject genomic data and the disease state, generating a report using the identified template, the report reporting treatments according to the hierarchical rule set, comparing the report to one or more approval criteria, and publishing the report when the approval criteria are satisfied.

Abstract: A zero-stop mechanism comprises first and second stop members and a movement limit member. The second stop member is releasably secured to an adjustment mechanism. The movement limit member extends around a turret assembly and has a substantially annular main body from which a lug extends. In a first rotational direction of the adjustment mechanism, the second stop member comes into contact with a first side of the lug whereby the main body is rotated in the first rotational direction until a second side of the lug comes into contact with the first stop member. In a second rotational direction of the adjustment mechanism, the second stop member comes into contact with the lug second side whereby the main body is rotated in the second rotational direction until the lug first side contacts the first stop member.

Abstract: A telescopic sight for a hand-held weapon comprises a housing for an optical system that presents a telescopic image to a user, and a zoom adjustment ring on the housing. The optical system has objective and ocular lens systems and between these an image erector lens system, and a sighting element bearing a graphic image pattern at either a first focal plane between the image erector lens system and the objective lens system or a second focal plane between the image erector lens system and the ocular lens system. An optical zoom system is linked to the zoom adjustment ring for effecting a change in magnification. The zoom adjustment ring is movable over the housing in opposite forward and rearward axial directions between a locked position and an unlocked position to adjust the zoom magnification. In the locked position interengaging formations between the ring and housing slides into engagement.

Abstract: A zero-stop mechanism comprises first and second stop members and a movement limit member. The second stop member is releasably secured to an adjustment mechanism. The movement limit member extends around a turret assembly and has a substantially annular main body from which a lug extends. In a first rotational direction of the adjustment mechanism, the second stop member comes into contact with a first side of the lug whereby the main body is rotated in the first rotational direction until a second side of the lug comes into contact with the first stop member. In a second rotational direction of the adjustment mechanism, the second stop member comes into contact with the lug second side whereby the main body is rotated in the second rotational direction until the lug first side contacts the first stop member.

Abstract: A display device support arm comprises: a securing component; a first support arm element pivotally attached to the securing component and coupling to an attachment means for receiving a coupling mechanism, incorporating a load indicator, at the lower end of a second support arm element. At the other end thereof is an attachment head and a display mounting head rotatably secured thereto. The mounting head includes a toothed arcuate surface to which there is pivotally mounted a trigger adapted to move one or more locking blocks out of biased engagement with the arcuate surface. Constant friction joints, a modified securing foot with tool holder, a tilt mechanism; a display rotation lock operably coupled to a display mounting interface; interchangeable rail assemblies; display mounting brackets for attachment to the rail assemblies; and methods of installing a support arm and setting a tilt mechanism are also defined.

Abstract: Provided herein are polynucleotides comprising sequence configured to bind to a CRISPR effector protein. Modulation of one or more modifications of the polynucleotides can be used to tune the activity of CRISPR effector proteins complexed with the polynucleotides.

Abstract: Provided herein are polynucleotides and CRISPR effector proteins configured to be covalently bound together in a CRISPR complex. The polynucleotides can be further modified to modulate the activity of the CRISPR complex. Modification of the polynucleotide and CRISPR effector protein can be used to improve the efficacy of target binding and/or cleavage.

Abstract: A method for attaching a heat-emitting device and a capillary heat pipe to a panel of a spacecraft wall is disclosed including the steps of: a) positioning a capillary heat pipe on a portion of the panel; attaching female attachment bodies to the panel, the female attachment bodies protruding relative to the capillary heat pipe; c) placing a thermally-conductive and self-curing paste over a portion of the capillary heat pipe or over a heat-emitting device; d) placing a heat-emitting device on the thermally-conductive and self-curing paste and on the female attachment bodies, said heat-emitting device bearing against and being in direct contact with the female attachment bodies, and e) attaching the heat-emitting device and said capillary heat pipe to the panel by attaching male attachment members to the female attachment bodies.

Abstract: Various embodiments of the present disclosure relate generally to providing virtual assistants. More specifically, various embodiments of the present disclosure relate to methods and systems for providing a simulation-based virtual advisor. In some embodiments, the systems and methods combine and/or integrate the functionality of a conversational virtual agent (e.g., a virtual assistant) with the functionality of a simulation virtual agent, to provide users, customers, or members with targeted, user-specific information in response to questions or other intentions posed by the users via messages exchanged between the users and the agents.

Abstract: A court tile for an athletic event and method of marking and installing the same. A court tile includes a plurality of playing surface boards, a plurality of first sub floor members are disposed between surface boards and a second sub floor layer. Resilient pads are provided for cushioning of the court tile. A sliding pad covers the resilient pads to permit positioning of the court tile on the venue floor. A system and method of marking a court pre-printing a segment of the court markings on a court tile. A method of creating a court with markings includes pre-marking each of a plurality of court tiles with a selected segment of a court marking for which the court tile is intended and assembling a court surface according to a predetermined placement of the pre-marked court tiles.

Abstract: Example implementations described herein can dynamically adapt to changing nature of sensor data traffic and through artificial intelligence (AI, strike a good tradeoff between reducing volume of sensed data, and retain enough data fidelity so that subsequent analytics applications perform well. The example implementations eliminate heuristic methods of setting sensing parameters (such as DAQ sampling rate, resolution etc.) and replaces them with an automated, AI driven edge solution core that can be readily ported on any Internet of Things (IoT) edge gateway that is connected to the DAQ.

Abstract: Systems and methods for collecting visual attention information are described. The methods comprise the steps of displaying a browser window on a display (210); estimating a user's (220) gaze point within the display (210); transforming the geometry of the estimated gaze point and/or the geometry of the browser window to a common coordinate system; identifying an object (215) in the browser window that corresponds to the estimated gaze point; and storing the estimated gaze point and data corresponding to the identified object (215).

Abstract: There is described a water purifying apparatus comprising: (i) at least one water inlet; (ii) an ultra-violet (UVC) radiation chamber connected to the water inlet(s); (iii) a plurality of UVC light emitting diodes (UVC-LEDs) for the emission of UVC light into the radiation chamber; (iv) a control to operate UVC-LEDs in use, and (v) at least one UVC-LED aging monitor to provide feedback to the control.

Abstract: The present disclosure relates to a Hemoglobin A (HBA) assay and a HBA genotyping decision tree matrix for implementation into clinical testing. Particularly, aspects are directed to obtaining raw data from the HBA assay performed on a plurality of samples, calculating a first set of probe ratios for each sample based on the raw data, identifying a number of reference samples to be combined as a synthetic reference sample based on the first set of probe ratios, calculating a second set of probe ratios for each sample of the plurality of samples based on the raw data and the synthetic reference sample, and determining, by the decision tree matrix, a HBA genotype for each sample based on the second set of probe ratios for each sample and copy number calling thresholds for sample probe/reference probe ratios associated with each probe of the plurality of probes.

Abstract: A heat transfer device is disclosed having a housing including a first main wall and a second main wall, the housing having a sealed internal cavity, a liquid contained in the internal cavity, and a mixer able to set the liquid in motion, the heat transfer device being able to be switched between a first state and a second state in which the liquid is in motion and transfers heat by convection between the first main wall and the second main wall, the thermal conductance between the first main wall and the second main wall in the first state being four times less than the thermal conductance between the first main wall and the second main wall in the second state.

Abstract: A new and distinct variety of grapevine plant named ‘Errante Noir’, particularly selected for its high resistance to Pierce's disease, as well as quality of fruit and wines produced is disclosed.

Abstract: A new and distinct variety of grapevine plant named ‘Paseante Noir’, particularly selected for its high resistance to Pierce's disease, as well as quality of fruit and wines produced is disclosed.

Abstract: A new and distinct variety of grapevine plant named ‘Caminante Blanc’, particularly selected for its high resistance to Pierce's disease, as well as quality of fruit and wines produced is disclosed.

Abstract: A new and distinct variety of grapevine plant named ‘Paseante Noir’, particularly selected for its high resistance to Pierce's disease, as well as quality of fruit and wines produced is disclosed.