Abstract: A system is disclosed for use in additively manufacturing an object. The system may have a support and a first module operatively mounted to an end of the support and configured to discharge a material during motion of the support to form an object. The system may also have a second module configured to sever the material, at least a third module configured to at least one of compact or cure the material, and an actuator configured to cause movement of the second and the at least a third modules relative to the first module.

Abstract: A network node includes at least one processor, at least one memory, and at least one network interface. The network node is configured to be within a plurality of network nodes communicatively coupled in a peer-to-peer network of network nodes implementing a distributed ledger. The network node is configured to be communicatively coupled to at least one remotely located computing device through the at least one network interface. The at least one processor is configured to determine a split ratio for a new split of security tokens held in at least one address of the distributed ledger. The at least one processor is also configured to store an indication of the split ratio without updating token balances for all of the at least one address in a list of addresses holding at least one of the security tokens.

Abstract: A fiber optic sensing (FOS) system and method. The system may include one or more interrogator units and a proximal wavelength division multiplexer (WDM) and a distal WDM optically connectable to the one or more interrogator units, an upgoing transmission fiber, a down-going transmission fiber, and one or more downhole sensing fibers. The method may include transmitting one or more light pulses from an interrogator unit, multiplexing the one or more light pulses from the interrogator unit with a proximal WDM into an upgoing transmission fiber and a down-going transmission fiber, and receiving the one or more light pulses with a distal WDM. The method may further include multiplexing the one or more light pulses from the upgoing transmission fiber and the down-going transmission fiber into one or more downhole sensing fibers and receiving backscatter light from at least one of the one or more downhole sensing fibers.

Abstract: A network node in a peer-to-peer network of nodes includes at least one processor, at least one memory, and at least one network interface. The at least one processor is configured to receive a request to transfer a security token and execute a plurality of compliance rules associated with the security token. At least one of the compliance rules is implemented using at least one smart contract. The at least one smart contract references a global registry. The at least one processor is also configured to transfer the security token based on the execution of the compliance rules. The global registry includes personally identifiable information (PII) hash(es) for each of at least one investor associated with the transfer of the security token. The hashes are committed to the distributed ledger and updated when PII of a respective one of the at least one investor changes.

Abstract: A system for predicting and summarizing medical events from electronic health records includes a computer memory storing aggregated electronic health records from a multitude of patients of diverse age, health conditions, and demographics including medications, laboratory values, diagnoses, vital signs, and medical notes. The aggregated electronic health records are converted into a single standardized data structure format and ordered arrangement per patient, e.g., into a chronological order. A computer (or computer system) executes one or more deep learning models trained on the aggregated health records to predict one or more future clinical events and summarize pertinent past medical events related to the predicted events on an input electronic health record of a patient having the standardized data structure format and ordered into a chronological order.

Abstract: A distributed acoustic system (DAS) may comprise an interrogator and an umbilical line attached at one end to the interrogator, a downhole fiber attached to the umbilical line at the end opposite the interrogator. The interrogator may further include a proximal circulator, a distal circulator connected to the proximal circulator by a first fiber optic cable, and a second fiber optic cable connecting the proximal circulator and the distal circulator.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: Disclosed herein, are prime editors for prime editing. Also disclosed are engineered reverse transcriptases and methods of using same for prime editing.

Abstract: The invention relates to functionalized polymers, a process for producing functionalized polymers and the use of functionalized polymers, especially in the field of personal care.

Abstract: A distributed acoustic system (DAS) may include an interrogator that includes two or more lasers, a pulser module disposed after and connected to each of the two or more lasers, a wavelength division multiplexer (WDM), wherein each of the pulser modules are connected to the WDM as inputs, and a downhole fiber attached to the WDM as an output and wherein the downhole fiber includes at least one sensing fiber. A method for increasing a sampling frequency may include identifying a length of a downhole fiber connected to an interrogator, generating and launching a light pulse from each of the two or more lasers the pulser module, and delaying an output from the pulser module into the downhole fiber by k N seconds, where k is a pulse repetition interval of the pulser module and N is equal to the two or more lasers.

Abstract: Systems for coupling two or more watercrafts, and assemblies comprised of systems and watercrafts. A watercraft coupling system includes a forward connector rod and an aft connector rod that are configured to be attached to forward and aft portions of adjacent first and second watercrafts, and may include additional components such as stabilization straps, nets, and rod cushions for safety and comfort. The system may be used to stably couple two or more watercrafts, such as recreational watercrafts, in a side-by-side arrangement to form a watercraft assembly that may be used by two or more users cooperatively.

Abstract: A method includes positioning a downhole tool in a borehole formed in a subsurface formation, wherein the downhole tool comprises a plurality of calipers arranged around a circumference of the downhole tool. The method includes detecting, using the plurality of calipers, a plurality of standoff measurements at different rotation angles and determining a plurality of apparent diameters of the borehole for the different rotation angles of the downhole tool based on the plurality of standoff measurements and at least one of a radius and a diameter of the downhole tool. The method includes determining a probability function based on the plurality of apparent diameters and determining a shape of the borehole based on the probability function.

Abstract: A shared ride system comprising a SIPV further comprising at least an integrated safety device wherein the safety device is a coupled safety helmet.

Abstract: A distributed acoustic system (DAS) may include an interrogator that includes two or more lasers, a pulser module disposed after and connected to each of the two or more lasers, a wavelength division multiplexer (WDM), wherein each of the pulser modules are connected to the WDM as inputs, and a downhole fiber attached to the WDM as an output and wherein the downhole fiber includes at least one sensing fiber. A method for increasing a sampling frequency may include identifying a length of a downhole fiber connected to an interrogator, generating and launching a light pulse from each of the two or more lasers the pulser module, and delaying an output from the pulser module into the downhole fiber by k N seconds, where k is a pulse repetition interval of the pulser module and N is equal to the two or more lasers.

Abstract: A method and system for fiber optic communication and sensing (FOCS) may include transmitting one or more measurement signals from an interrogator unit that is optically connected to a proximal wavelength division multiplexer (WDM), transmitting one or more communication signals from an information handling system that is optically connected to a proximal wavelength division multiplexer (WDM), multiplexing the one or more measurement signals and the one or more communication signals with the proximal WDM into a first fiber optic cable, and receiving the one or more measurement signals and the one or more communication signals with a distal WDM that is optically connected to the first fiber optic cable. The method may further include multiplexing the one or more measurement signals from the first fiber optic cable into one or more downhole sensing fibers and receiving backscatter light from at least one of the one or more downhole sensing fibers.

Abstract: A distributed acoustic system (DAS) method and system. The system may comprise an interrogator and an umbilical line comprising a first fiber optic cable and a second fiber optic cable attached at one end to the interrogator. The DAS may further include a downhole fiber attached to the umbilical line at the end opposite the interrogator and a light source disposed in the interrogator that is configured to emit a plurality of coherent light frequencies into the umbilical line and the downhole fiber. The method may include generating interferometric signals of the plurality of frequencies of backscattered light that have been received by the photo detector assembly and processing the interferometric signals with an information handling system.

Abstract: A journal of operations persistently stores a collection of user and machine interactions with documents, concepts within documents, and relationships/mentions among such documents and concepts. A knowledge graph or other visual expression can be used to provide an interactive format for user interactions with this information, and to visually display the accumulated information in the journal of operations on user's device of choice. Such accumulations are often called aggregations or aggregates. Both human users and computer users such as automated recommendation engines, machine learning algorithms, and the like can interact with the journal of operations to facilitate computer-assisted discovery and organization of data around a topic of interest to the human user. The resulting journal of operations and aggregations of those operations such as a knowledge graph or other visual expression(s) also provides a useful medium for sharing knowledge with other users and collaborating on investigation of a topic.

Abstract: A distributed acoustic system (DAS) method and system. The system may comprise an interrogator and an umbilical line comprising a first fiber optic cable and a second fiber optic cable attached at one end to the interrogator. The DAS may further include a downhole fiber attached to the umbilical line at the end opposite the interrogator and a light source disposed in the interrogator that is configured to emit a plurality of coherent light frequencies into the umbilical line and the downhole fiber. The method may include generating interferometric signals of the plurality of frequencies of backscattered light that have been received by the photo detector assembly and processing the interferometric signals with an information handling system.

Abstract: Methods of non-invasively imaging a subject using two or more antigen-binding constructs that selectively bind to immune cell markers are described.