Abstract: Batteries may cathode layers, anode layers, and at least one separator separating the cathode layers from the anode layers. A first cathode layer may have a larger surface area than a second cathode layer. A first anode layer may have a larger surface area than a second anode layer. A rigid shell may contain the cathode layers, anode layers, and at least one separator. The rigid shell may have a non-cuboidal and non-cylindrical shape that is curved about at least one axis that is non-normal to the cathode layers and anode layers. Various related batteries, wearable devices, systems, and methods are also disclosed.

Abstract: A capacitive sensing device is provided with a plurality of pads disposed on a base around a center of the base; a ground plane positioned above the plurality of pads; a rotor, positioned between the ground plane and the plurality of pads, configured to at least partially rotate about the center resulting in a portion of the rotor being positioned over different portions of the plurality of pads at different angles of rotation; and sensing circuitry connected to the plurality of pads in order to determine a position of the rotor; and wherein at least two pads of the plurality of pads are disposed in a shared arc defined from the center.

Abstract: The present disclosure relates to methods of loading an EV with a payload. In some aspects, the payload and the EV are mixed at a specific loading condition (e.g., at the disclosed salt concentrations, loading temperature, loading duration, payload feed concentration, and/or EV feed concentration), such that the amount of the payload that is associated with the exterior surface of the EV is increased. Also provided herein are methods for producing the extracellular vesicles and methods for using the extracellular vesicles to treat diseases or disorders.

Abstract: A subsidence monitoring system that employs an automated total monitoring stations (AMTS) in combination with a field-array of flush-mount prisms well-suited for monitoring settlement of roadways and other surfaces or structures. A method of installation of said field-array of flush-mount prism assemblies is also disclosed, along with tool for said installation.

Abstract: The present disclosure provides crystalline forms of 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile, pharmaceutical compositions comprising the crystalline forms, methods of using the crystalline forms, and processes for making the crystalline forms.

Abstract: Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, web portals, real-time live instruction, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The systems as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

Abstract: A system for producing hydrogen from water by a thermochemical cycle, for example the sulphuriodine cycle, comprises a reactor having reaction zones for implementing the reactions of the cycle. The reaction zones are interconnected by a fluid circuit and the reactor is configured to direct reaction product(s) from any reaction zone to another reaction zone to provide reactant(s) for the other reaction zone. Fluid is recirculated around the fluid circuit so that reaction product(s) from downstream reaction zone(s) are reused as reactant(s) for upstream reaction zone(s). Heat generated in reaction zone(s) is also reused in other reaction zone(s). The resulting system is energy efficient as well as being efficient in its use of reactants.

Abstract: A system for producing synthetic fuel comprises a reactor having a first reaction zone for implementing a first reaction in which carbon dioxide and hydrogen react to produce carbon monoxide and water, and at least one other reaction zone for implementing a second reaction in which carbon monoxide and hydrogen react to produce a fuel precursor, and a third reaction involving synthesizing fuel from said fuel precursor. The reaction zones are inter-connected in series by a fluid circuit is configured to circulate and recirculate fluid around the reactor to facilitate recycling of reactants and heat energy. The system facilitates low-energy. cost-efficient production of liquid e-fuels.

Abstract: The invention is related to the preparation of protected piperidine carboxylates suitable for use as intermediates that lead, via a series of additional process steps, including a sulfation of a hydroxy urea compound, to the preparation of the beta lactamase inhibitor (2S,5R)-7-oxo-N-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide.

Abstract: The present invention is directed to a computer-implemented method of automatically identifying the presence of one or more elements in a sample via optical emission spectroscopy.

Abstract: A swivel fitting assembly includes a female body providing a first connection end portion, and a male fitting body providing a second connection end portion. The male body and the female body are operatively coupled together to form a fluid passage between the first and second connection end portions, and are configured to permit relative rotation of the bodies relative to each other. A swivel lock mechanism is provided to rotationally lock or release the male body relative to the female body in response to a fluid pressure level in the fitting. The swivel lock includes a collar that transitions to a lock state and holds the male body when fluid pressure is at or above a predefined level. The collar transitions to a release state to enable relative rotation of the bodies when the pressure is below the predefined level.

Abstract: The present disclosure relates to methods for preparing extracellular vesicles (EVs). In particular, the methods provided herein comprise contacting a sample, which comprises EVs and one or more impurities, with a depth filter, wherein the depth filter is selected from a LA media grade depth filter, a SP media grade depth filter, or both. In some aspects, the methods further comprise one or more chromatography steps. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use.

Abstract: The present disclosure relates to compositions comprising extracellular vesicles (e.g., exosomes) that can comprise an antisense oligonucleotide (ASO), wherein the composition has an osmolarity that is lower than 450 mOsm/kg. Also provided herein are methods for producing the extracellular vesicles and methods for using the extracellular vesicles to treat and/or prevent a range of medical disorders.

Abstract: A UE can enable a VoWIFI service, receive hidden SSID information, and register with a core network via a RAN. The UE can monitor a first signal strength of a first signal from the RAN. The UE can scan for a second signal from a WLAN, and when found, can measure a second signal strength of the second signal. The UE can determine whether the first signal strength is at or below a first threshold. If so, and if the WLAN is untrusted, the UE can probe it with the hidden SSID information. If the untrusted WLAN responds, the UE can send an access request to an untrusted WLAN access point. The UE can receive, via the untrusted WLAN access point, an authentication challenge from an ePDG. If the UE passes the authentication challenge, the UE can register with the core network via the untrusted WLAN and the ePDG.

Abstract: The present invention is directed to a computer-implemented method of automatically identifying the presence of one or more elements in a sample via optical emission spectroscopy.

Abstract: An encoder may be configured to receive a first input from a user. The encoder may include a first user input area. A configurator may be configured to communicate with the encoder and the encoder may be configured to communicate with a CPU. The encoder may receive the first input from the user at the first user input area based on an encoder configuration defined by the configurator. The encoder may communicate the first input to the CPU based on the encoder configuration defined by the configurator. A panel may be configured to receive a first input from a user. The panel may include a plurality of input areas. A portable computing device may comprise a configurator. The portable computing device may be configured to communicate with a CPU.

Abstract: Systems and methods are disclosed for managing skin in a subterranean wellbore. In an embodiment, the method includes oscillating a drawdown pressure of the subterranean wellbore in a predetermined pattern that comprises a plurality of alternating drawdown pressure increases and drawdown pressure decreases. The drawdown pressure increases of the predetermined pattern comprise increasing the drawdown pressure at a first rate, and the drawdown pressure decreases of the predetermined pattern comprise decreasing the drawdown pressure at a second rate that is different from the first rate.

Abstract: Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, web portals, real-time live instruction, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The systems as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

Abstract: A subsidence monitoring system that employs an automated total monitoring stations (AMTS) in combination with a field-array of flush-mount prisms well-suited for monitoring settlement of roadways and other surfaces or structures. A method of installation of said field-array of flush-mount prism assemblies is also disclosed, along with tool for said installation.

Abstract: The present invention comprises a polymer and/or polymer composite based sleeve to be fitted between an extended body, such the neck, trunnion, and/or stem of a hip implant, and a receiving body, such as a femoral head in a hip implant, that reduces wear, decreases toxic material from wear debris, enhances the mechanical connection of the extension and receiving body, reduces or eliminates impingement with receiving body, delocalize stress concentrations, and may also serve as a modifying junction between an extension and receiving body of unmatched size. The polymeric based sleeve presently disclosed comprises an inert and/or biologically favorable material which may be used in its virgin form or contain biocompatible additives. In order to best match patient and implant requirements, modifications may be made in the length, thickness, composition, as well as the presence of a taper, or lack thereof, in order to be compatible with existing devices.