Patents by Inventor Andrew Zhang

Andrew Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12084517
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: June 7, 2023
    Date of Patent: September 10, 2024
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20240209451
    Abstract: Provided herein include a method, kit and system capable of detecting one or multiple human cancers with high accuracy. After an expression profile of an miRNA biomarker set comprising one or more miRNAs is determined based on a liquid biopsy sample from a subject, a diagnostic index is calculated, based on which the subject can be classified as having cancer or not. In the miRNA biomarker set, each miRNA is picked from a 500-miRNA set. A 4-miRNA biomarker model demonstrates exceptionally high sensitivities of 99.0-100% for lung and gastric cancers, 83.0-99.0% for biliary tract, bladder, colorectal, esophageal, glioma, liver, pancreatic, and prostate cancers, and 68.2-72.0% for ovarian cancer and sarcoma, while maintaining 99.3% specificity.
    Type: Application
    Filed: December 11, 2023
    Publication date: June 27, 2024
    Applicant: MIRONCOL DIAGNOSTICS, INC.
    Inventors: Andrew ZHANG, Hai HU
  • Patent number: 11982625
    Abstract: A system for measurement is provided. The system includes a first optical path configured to supply first light pulses with a first range of wavelengths; a second optical path configured to supply second light pulses with a second range of wavelengths shorter than the first range of wavelengths; an optical I/O unit configured to emit the first light pulses and the second light pulses to a target and acquire a light from the target to detect CARS light pluses from the target by a detector; and a first phase modulating unit configured to vary phase differences between the first light pulses and the second light pulses as the first light pulses and the second light pulses are emitted via the optical I/O unit.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: May 14, 2024
    Assignee: ATONARP INC.
    Inventors: David Anderson, Mateusz Plewicki, Dmitriy Churin, Anand Pandurangan, Andrew Zhang, Lukas Brueckner, Prakash Sreedhar Murthy
  • Publication number: 20240067756
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: June 7, 2023
    Publication date: February 29, 2024
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20230351335
    Abstract: The systems and methods provide assistance in employee interactions. The systems and methods automatically schedule meetings between a manager and a report in response to changes in human resource data. The systems and methods track the meetings between the manager and the report during a time period and obtain meeting minutes for the meetings. The systems and methods analyze the meeting minutes and automatically generate feedback based on the analysis of the meeting minutes. The feedback is provided to the report or the manager.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Inventors: Satish CHANDRA, Yaming LIU, Manish RAJANGAM, Rahul KUMAR, Avneesh RAI, Andrew ZHANG, Shuming SUN, Saleha Iqbal HUSSAIN, Swati SHARMA, Akash RATHORE
  • Patent number: 11725064
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: August 15, 2023
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 11576981
    Abstract: The present application is directed to compounds of Formula (I)-(VIII): compositions comprising these compounds and their uses, for example as medicaments and/or diagnostics.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: February 14, 2023
    Assignee: ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR)
    Inventors: Rima Al-awar, Andrew Zhang, Ahmed Mamai
  • Publication number: 20220317044
    Abstract: A system for measurement is provided. The system includes a first optical path configured to supply first light pulses with a first range of wavelengths; a second optical path configured to supply second light pulses with a second range of wavelengths shorter than the first range of wavelengths; an optical I/O unit configured to emit the first light pulses and the second light pulses to a target and acquire a light from the target to detect CARS light pluses from the target by a detector; and a first phase modulating unit configured to vary phase differences between the first light pulses and the second light pulses as the first light pulses and the second light pulses are emitted via the optical I/O unit.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 6, 2022
    Applicant: ATONARP INC.
    Inventors: David ANDERSON, Mateusz PLEWICKI, Dmitriy CHURIN, Anand PANDURANGAN, Andrew ZHANG, Lukas BRUECKNER, Prakash Sreedhar MURTHY
  • Publication number: 20220023428
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: May 17, 2021
    Publication date: January 27, 2022
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 11014992
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: May 25, 2021
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20200397916
    Abstract: The present application is directed to compounds of Formula (I)-(VI): (I), (II), (III), (IV), (V) (VI), (VII) and (VIII), compositions comprising these compounds and their uses, for example as medicaments and/or diagnostics.
    Type: Application
    Filed: December 6, 2018
    Publication date: December 24, 2020
    Applicant: Ontario Institute for Cancer Research (OICR)
    Inventors: Rima Al-Awar, Andrew Zhang, Ahmed Mamai
  • Publication number: 20200354476
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 12, 2020
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20200352767
    Abstract: A device for controlling the weight of a body comprises a net-shaped basket system. The basket is custom made for each patient by 3D printing technology using silicone material based on a physician's assessment of height, weight, and energy consumption of obese patients. With several MEMS pressure sensors embedded inside the basket material, it is placed on the outer wall of the patient's stomach by laparoscopic surgery. The sensor can measure the pressure of the stomach in real time. When the patient eats too much, the pressure reaches the threshold level set by the doctor, and the monitor will immediately remind the obese person to stop eating. If the patient ignores the warning and continues to eat, the basket will reach its distensible limit, forcing a patient to stop taking food. Food intake of obese patients can be controlled quantitatively via the basket system and the gastric motility can be diagnosed via the pressure-time curve.
    Type: Application
    Filed: May 7, 2019
    Publication date: November 12, 2020
    Inventor: Andrew Zhang
  • Patent number: 10703823
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: July 7, 2020
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20190127487
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: July 26, 2018
    Publication date: May 2, 2019
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 10066026
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: September 4, 2018
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 9542196
    Abstract: A communication terminal is described comprising a modem; a first memory configured to store configuration data for the modem; a second memory configured to store a system boot firmware; and a processor configured to execute the system boot firmware and to read the configuration data from the memory and provide it for the modem under the control of the system boot firmware.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: January 10, 2017
    Assignee: INTEL CORPORATION
    Inventors: Andrew Zhang, Karunakara Karu Kotary
  • Publication number: 20160347863
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: March 28, 2016
    Publication date: December 1, 2016
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 9296708
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: March 29, 2016
    Assignee: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Publication number: 20150248296
    Abstract: A communication terminal is described comprising a modem; a first memory configured to store configuration data for the modem; a second memory configured to store a system boot firmware; and a processor configured to execute the system boot firmware and to read the configuration data from the memory and provide it for the modem under the control of the system boot firmware.
    Type: Application
    Filed: February 28, 2014
    Publication date: September 3, 2015
    Inventors: ANDREW ZHANG, KARUNAKARA KARU KOTARY