Abstract: A method includes receiving a request. The request is encrypted to generate an encrypted request. The encrypted request includes a version information for a first software package deployed in a standalone computing system, and a region information and a hardware information for the standalone computing system. The encrypted request is sent to a respective regional data center of a cloud computing system based on the region information of the first software package. A second software package is identified among software packages stored in the respective regional data center. The second software package corresponds to the hardware information of the first software package. The version information of the first software package is compared to a version information of the second software package. In response to identifying that the second software package is more recent than the first software package, the second software package is deployed to the standalone computing system.

Abstract: A cardiac implant includes a frame forming an inner lumen and sized for delivery into a blood vessel and a covering extending at least partially along the frame to at least partially restrict lateral blood flow from one or more branching blood vessels into the blood vessel. The covering forms one or more folds at or near a distal end of the frame.

Abstract: Provided herein are peptides and conjugates (e.g., radiopharmaceutical conjugates) having avidity for a somatostatin receptor and uses thereof. The conjugate can comprise a 6-mer peptide, such as a monocyclic 6-mer peptide, a metal chelator, and optionally a linker connecting the peptide to the chelator. The radiopharmaceutical conjugate can further comprise a radionuclide bound to the metal chelator. Further provided herein are methods of preparing the conjugates, and methods of treating cancer by administering the described conjugates to a subject in need thereof.

Abstract: The present invention relates to polyethylene mixed color blend having (i) a melt flow rate (ISO1133, 5.0 kg; 190° C.) of 0.1 to 10 g/10 min, (ii) a density of 950 to 990 kg/m3 (ISO1183); (iii) a C2 fraction in amount of at least 95.0 wt.-%, as measured by 13C-NMR of the d2-tetrachloroethylene soluble fraction; (iv) a homopolymer fraction (HPF) content determined according to Chemical Composition Analysis by Cross Fractionation Chromatography (CFC) in the range from 73.0 to 91.0 wt.-%; (v) a copolymer fraction (CPF) content determined according to Chemical Composition Analysis Cross Fractionation Chromatography (CFC) in the range from 10.0 to 22.0 wt.-%; (vi) a total content of heavy metals selected from Cr, Cd, Hg and Pb of not more than 100 ppm with respect to the total polyethylene blend, as measured by x-ray fluorescence (XRF); and (vii) a Full Notch Creep Test (FNCT) determined according to ISO 16770-2019 at 50° C. and 6.0 MPa in 2 wt.-% Arkopal N100, of at least 3.

Abstract: The present invention concerns a polypropylene mixed color blend having (i) a crystalline fraction (CF) content determined according to CRYSTEX QC analysis, in the range from 85.0 to 95.0 wt.-%, (ii) a soluble fraction (SF) content in the range from 5.0 to 15.0 wt.-%, (iii) a total ethylene content (C2), in the range from 2.0 to 10.0 wt.-%, (iv) said crystalline fraction (CF) has a propylene content (C3 (CF)) as determined by FT-IR spectroscopy calibrated by quantitative 13C-NMR spectroscopy, in the range from 93.0 to 99.0 wt.-%; (v) said crystalline fraction (CF) has an ethylene content (C2 (CF)), as determined by FT-IR spectroscopy calibrated by quantitative 13C-NMR spectroscopy, in the range from [C2]-3.4 wt.-% to [C2]-0.2 wt.-%, wherein [C2] is the total ethylene content (C2) defined in (iii), (vi) a CIELAB color space (L*a*b*) measured according to DIN EN ISO 11664-4, of L* from 30.0 to 73.0; a* from ?10 to 25; and b* from ?5 to 20.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, and processes for making such modulators.

Abstract: The present Specification is directed to devices for controlling the phase of a light signal in a surface waveguide of a planar-lightwave circuit by controlling a stress in the waveguide material. Phase controllers disclosed can impart stresses of opposite signs in a material such that a desired effect on the refractive index of an optical material can be accentuated. As a result, a greater change in the refractive index of the material can be realized in a phase controller that requires less chip real estate and/or at lower voltages. In some embodiments, a phase-control module includes a pair of complimentary stress-optic phase controllers, one having electrodes disposed on the top and bottom of a piezoelectric layer, while the other has electrodes disposed only on top of the piezoelectric layer. As a result, the phase controllers impart stress of opposite sign in the material beneath them.

Abstract: A medical implant for managing blood flow through a blood vessel comprises a stent body forming a proximal portion and a tapered distal end, the tapered distal end being angled relative to the proximal portion to face a direction of blood flow and limit blood flow into an inner lumen of the stent body, and the tapered distal end having a flexible structure to allow the tapered distal end to bend and straighten in response to blood flow, and a covering extending along the stent body.

Abstract: A method and system for security assessment include a simulator configured to simulate a warping-based backdoor attack and an evaluation module configured to evaluate security and output a warning about a backdoor risk. The simulator, which comprises a warping unit and a backdoor model, is configured to generate a warping field, the warping unit is configured to receive the clean image and the warping field as inputs and output the warped backdoor image and the simulator is configured to train the backdoor model using the warped backdoor image.

Abstract: A process for collecting and storing quality control data in a mechanical polyolefin recycling process, a process for optimising the performance of the mechanical polyolefin recycling process in response to said quality control data, an adjustment control model and a use of quality control data for optimising the performance of the mechanical polyolefin recycling process.

Abstract: A method includes intercepting requests, which are analyzed to identify authenticated and suspicious requests. The suspicious requests are grouped into request groups based on respective geolocation information. A rate of requests is determined for a request group. In response to determining that the rate of requests is less than or equal to a request rate threshold, parameters of a suspicious request of the request group are analyzed to determining values of the parameters. In response to determining that the value of the parameters do not match with respective malicious parameter values stored in a block list, the suspicious request is analyzed using a neural network to identify if the suspicious request is legitimate or malicious. In response to identifying that the suspicious request is malicious, a notification indicating that the suspicious request is identified as malicious is sent, and the values of the parameters are added to the block list.

Abstract: A method includes intercepting requests. The requests are analyzed to identify authenticated requests. Remaining requests are identified as suspicious requests. The suspicious requests are grouped into request groups based on respective geolocation information. A first rate of requests is determined for a first request group. In response to determining that the first rate of requests is less than or equal to a request rate threshold, parameters of a first suspicious request of the first request group are analyzed to determining values of the parameters. In response to determining that the values of the parameters are not within respective acceptable parameter value ranges, the first suspicious request is analyzed using a neural network to identify if the first suspicious request is legitimate or malicious. In response to identifying that the first suspicious request is malicious, a first notification indicating that the first suspicious request is identified as malicious is send.

Abstract: Polyethylene blend with defined CIELAB color.

Abstract: Aspects of the present disclosure describe integrated-optics-based phase controllers comprising waveguides whose cores have one or more cavities, thereby enabling them to exhibit an enhanced photo-elastic effect and/or increased stress-induced deformation in at least one region. Waveguides in accordance with the present disclosure are particularly well suited for use in stress-optic phase controllers suitable for use in systems such as microwave photonics, LIDAR and the like.

Abstract: A method includes receiving a request. The request is encrypted to generate an encrypted request. The encrypted request includes a version information for a first software package deployed in a standalone computing system, and a region information and a hardware information for the standalone computing system. The encrypted request is sent to a respective regional data center of a cloud computing system based on the region information of the first software package. A second software package is identified among software packages stored in the respective regional data center. The second software package corresponds to the hardware information of the first software package. The version information of the first software package is compared to a version information of the second software package. In response to identifying that the second software package is more recent than the first software package, the second software package is deployed to the standalone computing system.

Abstract: The present disclosure is directed to systems and methods for controlling the phase of at least one light signal in a planar-lightwave circuit (PLC) via a stress-optic (SO) phase controller. SO phase controllers in accordance with the present disclosure include a stress-inducing element disposed on a dome-shaped surface of the upper cladding of an integrated-optics-based waveguide, where the dome surface includes little or no linear portion. Such a dome-shaped surface improves the effectiveness with which the stress-inducing element can impart stress in the waveguide materials, thereby reducing the drive voltage and/or interaction length required to induce a given phase shift as compared to the prior art.

Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.

Abstract: A method and system for training a machine learning model for point of gaze prediction simultaneously analyzes the image of the scene and the image of the driver's face using the machine learning model to generate a point of gaze of a driver in traffic environments. The machine learning model comprises a camera calibration module that can compute an embedding vector that represents the spatial configuration between the driver and the camera system. The camera calibration module improves the overall model's performance, which is jointly trained end to end.

Abstract: A polypropylene composition (C) obtainable by blending: a mixed-plastics polypropylene blend with a virgin polypropylene homopolymer.

Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.