Abstract: Disclosed herein are techniques related to automatic real-time meal detection. In some embodiments, the techniques involve obtaining a plurality of glucose concentration values and a plurality of plasma insulin concentration estimations, each glucose concentration value corresponding with a respective plasma insulin concentration estimation; generating an output based on applying a meal detection model to the plurality of glucose concentration values and the plurality of plasma insulin concentration estimations; and determining, based on the output, that a glucose concentration value of the plurality of glucose concentration values corresponds to an ongoing glycemic response to a meal.

Abstract: A method of controlling an insulin infusion device involves controlling the device to operate in an automatic basal insulin delivery mode, obtaining a blood glucose measurement for the user, and initiating a correction bolus procedure when: the measurement exceeds a correction bolus threshold value; and a maximum basal insulin infusion rate is reached during the automatic basal insulin delivery mode. The correction bolus procedure calculates an initial correction bolus amount, and scales the initial amount to obtain a final correction bolus amount, such that a predicted future blood glucose level resulting from simulated delivery of the final correction bolus amount exceeds a low blood glucose threshold level. The final amount is delivered to the user during operation in the automatic basal insulin delivery mode.

Abstract: Techniques related to temporary setpoint values are disclosed. The techniques may involve causing operation of a fluid delivery device in a first mode for automatically delivering fluid to a patient based on a first target glucose value. Additionally, the techniques may involve obtaining a second target glucose value. The second target glucose value may be a temporary target glucose value to be used for a specified period of time to regulate fluid delivery to the patient, and the second target glucose value may be greater than the first target glucose value. The techniques may further involve causing, based on obtaining the second target glucose value, operation of the fluid delivery device in a second mode for automatically delivering fluid to the patient. The second mode may be for reduced fluid delivery during the specified period of time.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves predicting, by a control system associated with the infusion device, a future occurrence of an event based at least in part on historical data associated with the patient, and prior to the future occurrence of the event, automatically adjusting a control parameter for operating the infusion device based at least in part on the event and automatically operating an actuation arrangement of the infusion device to deliver the fluid to the patient based at least in part on a current measurement of the physiological condition and the adjusted control parameter.

Abstract: A semiconductor device and fabrication method are described for integrating a nanosheet transistor with a capacitor or nonvolatile memory cell in a single nanosheet process flow by forming a nanosheet transistor stack (11-18) of alternating Si and SiGe layers which are selectively processed to form epitaxial source/drain regions (25A, 25B) and to form gate electrodes (33A-D) which replace the silicon germanium layers in the nanosheet transistor stack, and then selectively forming one or more insulated conductive electrode layers (e.g., 37/39, 25/55, 64/69) adjacent to the nanosheet transistor to define a capacitor or nonvolatile memory cell that is integrated with the nanosheet transistor.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining one or more measurement values of a physiological condition in the body of a user during an initial monitoring period and determining a fasting reference value for a metric based on the one or more measurement values. After the initial monitoring period, the method continues by obtaining an updated measurement value during a fasting period, determining a current value for the metric based at least in part on the updated measurement value, and generating a notification in response to a deviation between the current value and the fasting reference value exceeding a threshold indicative of insertion site loss or other loss of effectiveness.

Abstract: A temperature exposure detection system includes a plurality of nonvolatile memory cells. The memory includes memory read circuitry for reading the plurality of memory cells to determine a data retention error rate of the plurality of memory cells. The temperature exposure detection system determines a temperature exposure of the system based on the determined data retention error rate.

Abstract: The presently disclosed subject matter relates to devices, systems, and methods of producing an improved fluid flow assembly and liquid/gas diffusion layer in solid polymer electrolyte electrochemical cells. In one aspect, a fluid flow assembly for a polymer electrolyte water electrolyzer includes a flow field having an inlet, an outlet, and a plurality of discrete lands arranged within the flow field. A liquid/gas diffusion layer is positioned in communication with the flow field between the inlet and the outlet, the liquid/gas diffusion layer having a solid substrate through which a plurality of pores is formed. The disclosed bipolar plate flow field and liquid/gas diffusion layer could work together or separately with other types of porous transport layers or bipolar plates to enhance the water/gas transport. In these configurations, the lands can be arranged and configured such that the plurality of pores are substantially unobstructed by the lands.

Abstract: A memory includes an array of resistive memory cells and circuitry for setting a write parameter for improving write effectiveness to the cells of the memory array. The circuitry performs a write parameter setting routine that determines a midpoint resistance of a memory state of cells of the array and determines a write efficiency of a weak write operation to cells of the array. Based on the determined midpoint resistance and the determined write efficiency, the circuit sets a write parameter level for subsequent writes to cells of the array.

Abstract: Infusion devices and related medical devices, patient data management systems, and methods are provided for monitoring a physiological condition of a patient. An exemplary infusion device includes an actuation arrangement operable to deliver fluid to a user, a communications interface to receive measurement data indicative of a physiological condition of the user, a sensing arrangement to obtain contextual measurement data, and a control system coupled to the actuation arrangement, the communications interface and the sensing arrangement to determine a command for autonomously operating the actuation arrangement in a manner that is influenced by the measurement data and the contextual measurement data and autonomously operate the actuation arrangement in accordance with the command to deliver the fluid to the user.

Abstract: A magnetoresistive random-access memory (MRAM) device includes an array of MRAM bit cells grouped into words, each word having specified number of data bit cells, error correction code (ECC) bit cells, and at least two inversion indicator bit cells, the inversion indicator bit cells being redundant of each other; and a memory controller. The memory controller is configured to, for each of the words, set the inversion indicator bit cells to indicate whether the number of data bit cells in a word having a zero value is greater than the number of data bit cells having a one value, invert the zeroes and ones in the bit cells when the inversion indicator bit cells are set to indicate a greater number of zeroes than ones in the data bit cells of the word, and revert the data bit cells to their value before the zeroes and ones were inverted.

Abstract: A processor-implemented method for closed-loop control in steady-state conditions includes determining, based on data including historical bolus information but excluding historical basal information, an amount of unmetabolized therapeutic substance in a patient; determining, based on a difference between a most recent measurement of a physiological condition of the patient and a target value for the physiological condition, a first amount or rate of a basal dosage for delivery to the patient; adjusting, based on the amount of unmetabolized therapeutic substance, the first amount or rate of the basal dosage to determine a second amount or rate of the basal dosage; and causing delivery of the second amount or rate of the basal dosage based on communicating the second amount or rate in a delivery command.

Abstract: A nanosheet semiconductor device and fabrication method are described for integrating the fabrication of nanosheet transistors (71) and capacitors/sensors (72) in a single nanosheet process flow by forming separate transistor and capacitor/sensor stacks (12A-16A, 12B-16B) which are selectively processed to form gate electrode structures (68A-C) which replace remnant SiGe sandwich layers in the transistor stack, to form silicon fixed electrodes using silicon nanosheets (13C, 15C) on a first side of the capacitor/sensor stack, and to form SiGe fixed electrodes using SiGe nanosheets (12C, 14C, 16C) from the middle of remnant SiGe sandwich layers in the capacitor/sensor stack (e.g., 16-2) which are separated from the silicon fixed electrodes by selectively removing top and bottom SiGe nanosheets (e.g., 16-1, 16-3) from the remnant SiGe sandwich layers in the capacitor/sensor stack.

Abstract: A semiconductor device and fabrication method are described for integrating stacked top and bottom nanosheet transistors by providing a nanosheet transistor stack having bottom and top Si/SiGe superlattice structures (11-14, 17-20) which are separated from one another by a barrier oxide layer (15) and which are separately processed to form bottom gate electrodes having a first gate structure (40A-B) in the bottom Si/SiGe superlattice structures and to form top gate electrodes having a second, different gate structure (46A-B) in the top Si/SiGe superlattice structures.

Abstract: A semiconductor device and fabrication method are described for integrating stacked top and bottom nanosheet transistors by providing a nanosheet transistor stack having bottom and top Si/SiGe superlattice structures (11-14, 17-20) which are separated from one another by a barrier oxide layer (15) and which are separately processed to form first remnant silicon germanium nanosheet layers (12, 14) in the bottom Si/SiGe superlattice structures having a first gate length dimension (DG1) and to form second remnant silicon germanium nanosheet layers (18, 20) in the top Si/SiGe superlattice structures having a second, smaller gate length dimension (DG2) so that the nanosheet transistor stack may then be processed to simultaneously form bottom and top gate electrodes which replace, respectively, the first and second remnant silicon germanium nanosheet layers.

Abstract: A semiconductor device and fabrication method are described for integrating a nanosheet transistor with a capacitor or nonvolatile memory cell in a single nanosheet process flow by forming a nanosheet transistor stack (11-18) of alternating Si and SiGe layers which are selectively processed to form epitaxial source/drain regions (25A, 25B) and to form gate electrodes (33A-D) which replace the silicon germanium layers in the nanosheet transistor stack, and then selectively forming one or more insulated conductive electrode layers (e.g., 37/39, 25/55, 64/69) adjacent to the nanosheet transistor to define a capacitor or nonvolatile memory cell that is integrated with the nanosheet transistor.

Abstract: A nanosheet MEMS sensor device and method are described for integrating the fabrication of nanosheet transistors (61) and MEMS sensors (62) in a single nanosheet process flow by forming separate nanosheet transistor and MEMS sensor stacks (12A-16A, 12B-16B) of alternating Si and SiGe layers which are selectively processed to form gate electrodes (49A-C) which replace the silicon germanium layers in the nanosheet transistor stack, to form silicon fixed electrodes using silicon layers (13B-2, 15B-2) on a first side of the MEMS sensor stack, and to form silicon cantilever electrodes using silicon layers (13B-1, 15B-1) on a second side of the MEMS sensor stack by forming a narrow trench opening (54) in the MEMS sensor stack to expose and remove remnant silicon germanium layers on the second side in the MEMS sensor stack.

Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

Abstract: A system for controlling fluid delivery includes one or more processors, and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of: identifying a residual value indicative of a difference between a first value and a second value, the first value corresponding to a physiological condition of a patient before delivery of a bolus amount of fluid, and the second value corresponding to a physiological condition of the patient after delivery of the bolus amount of the fluid, determining a ratio adjustment factor based on the residual value, and determining, based on the ratio adjustment factor, an updated value for a ratio that influences delivery of bolus amounts of the fluid.