Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining one or more measurement values of a physiological condition in the body of a user during an initial monitoring period and determining a fasting reference value for a metric based on the one or more measurement values. After the initial monitoring period, the method continues by obtaining an updated measurement value during a fasting period, determining a current value for the metric based at least in part on the updated measurement value, and generating a notification in response to a deviation between the current value and the fasting reference value exceeding a threshold indicative of insertion site loss or other loss of effectiveness.

Abstract: A sparse streaming system provides a first-class means for sparse metadata to be added to streaming media presentations and to be delivered using an integrated data channel that is cacheable using readily available HTTP-based Internet caching infrastructure for increased scalability. The sparse streaming system stores a reference to a sparse track within a continuous track. If a continuous fragment arrives at the client that refers to a sparse fragment that the client has not yet retrieved, then the client requests the sparse fragment. In addition, each sparse fragment may include a backwards reference to the sparse fragment created immediately prior. The references in the continuous fragments make the client aware of new sparse track fragments, and the backwards references in the sparse track fragments ensure that the client has not missed any intervening sparse track fragments.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.

Abstract: A data processing system includes a backup nonvolatile memory (NVM), a random access memory (RAM), and a controller. The RAM includes a plurality of partitions, each partition having a different corresponding backup frequency. The controller is configured to back up the contents of each partition of the RAM to the backup NVM in accordance with the corresponding backup frequency.

Abstract: An integrated circuit includes an array of resistive non-volatile memory cells having a plurality of word lines, a plurality of bit lines, and a plurality of source lines. The integrated circuit includes a sense amplifier coupled to a first bit line of the plurality of bit lines and a corresponding first source line of the plurality of source lines. When a memory cell coupled to the first bit line is selected for a read operation, the sense amplifier is configured to, during a calibration phase of the read operation, store a first voltage representative of a leakage current on the first source line. The sense amplifier is also configured to, during a sense phase of the read operation, apply the stored first voltage to the first bit line and provide a first sense amplifier output indicative of a logic state of the selected memory cell.

Abstract: An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.

Abstract: A semiconductor device includes an array of memory cells, and a reference voltage generation circuit including a first set of reference memory cells coupled to a first bit line, a second set of reference memory cells coupled to a second bit line, a first capacitor having a first terminal coupled to the first bit line, and a second terminal, a second capacitor having a first terminal coupled to the second terminal of the first capacitor at a first node and a second terminal coupled to the second bit line, an amplifier including a first input selectively coupled to the first node and a second input coupled to an output of the amplifier that provides reference voltage used by sense amplifiers, and a third capacitor including a first terminal coupled to the output of the amplifier and a second terminal coupled to a first supply voltage.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves identifying a current site location on the body of the user associated with a sensing arrangement providing sensed measurements of a physiological condition in the body of the user at the current site location, determining one or more performance metrics associated with the current site location corresponding to operation of the infusion device to deliver the fluid in response to the sensed measurements, and providing sensor site feedback in a manner that is influenced by the one or more performance metrics. In one or more embodiments, the sensor site feedback includes recommended sensor site locations for rotation or replacement of the sensing arrangement determined based on historical data associated with the user for different sensor site locations.

Abstract: A filtration device includes features for robust filtering capability. In particular, the filtration device includes a filter medium having mixed matrix membranes that include hollow fiber membranes embedded with adsorbents such that the filter medium provides both mechanical and adsorption capability.

Abstract: A filter manifold includes a housing and a shuttle. The shuttle is disposed within the housing such that the shuttle is movable relative to the housing between a plug position and a flow position along an axial direction. The shuttle is also coupled to the housing such that the shuttle is non-rotatable relative to the housing about the axial direction. A spring is disposed within the housing. The spring is connected to the shuttle such that the tension spring urges the shuttle towards the plug position. The shuttle is positioned at the flow position of the shuttle when a filter cartridge is coupled to the filter manifold.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves identifying a condition of the user that is likely to influence a response to the fluid in the body of the user and classifying the condition as a first type of a plurality of types of conditions. After classifying the condition as the first type, the method continues by adjusting control information for operating the infusion device based on the first type and operating the infusion device to deliver the fluid to the user in accordance with the adjusted control information.

Abstract: A memory circuit includes a plurality of memory tiles. Each memory tile in the plurality of memory tiles includes a plurality of bit cells and a control circuit coupled to the plurality of bit cells. The control circuit is configured to provide latched data to the plurality of bit cells during write operations. A first write control line is coupled to the control circuit in a first memory tile, and the first write control line is configured to initiate a first write operation in the first memory tile. And a second write control line is coupled to the control circuit in a second memory tile, and the second write control line configured to initiate a second write operation in the second memory tile. The second write operation may be initiated before the first write operation is completed.

Abstract: A refrigerator appliance and extraction is provided herein. The extraction fluid assembly may include a fluid tank, an open container, a filter assembly, a dispenser housing, and a precision doser. The fluid tank may define an extraction chamber to receive a liquid solvent. The open container may be selectively disposed on the fluid tank to hold an additive within the extraction chamber. The filter assembly may be positioned beneath the fluid tank along a vertical direction in fluid communication with the extraction chamber. The dispenser housing may support the filter assembly. The dispenser housing may also define a dispensing chamber positioned beneath the filter assembly in fluid communication therewith. The precision doser may be in fluid communication with the dispensing chamber to direct an extraction fluid therefrom.

Abstract: An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.

Abstract: Infusion devices and related medical devices, patient data management systems, and methods are provided for monitoring a physiological condition of a patient. An exemplary infusion device includes an actuation arrangement operable to deliver fluid to a user, a communications interface to receive measurement data indicative of a physiological condition of the user, a sensing arrangement to obtain contextual measurement data, and a control system coupled to the actuation arrangement, the communications interface and the sensing arrangement to determine a command for autonomously operating the actuation arrangement in a manner that is influenced by the measurement data and the contextual measurement data and autonomously operate the actuation arrangement in accordance with the command to deliver the fluid to the user.

Abstract: A memory system includes a main memory array, a redundant memory array, and a content addressable memory (CAM). The CAM includes a plurality of entries, wherein each entry includes a plurality of column address bits and a plurality of maskable row address bits. When an access address for a memory operation matches an entry of the CAM, the memory system is configured to access the redundant memory array to perform the memory operation.

Abstract: Disclosed are methods, apparatuses, etc. for calibrating glucose monitoring sensors and/or insulin delivery systems. In certain example embodiments, blood glucose reference samples may be correlated with sensor measurements with regard to a delay associated with the sensor measurements. In certain other example embodiments, a blood-glucose concentration in a patient may be determined based, at least in part, on one or more probability models, one or more functions for estimating blood-glucose concentrations, and/or blood glucose reference sample-sensor measurement pairs.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining one or more measurement values of a physiological condition in the body of a user during an initial monitoring period and determining a fasting reference value for a metric based on the one or more measurement values. After the initial monitoring period, the method continues by obtaining an updated measurement value during a fasting period, determining a current value for the metric based at least in part on the updated measurement value, and generating a notification in response to a deviation between the current value and the fasting reference value exceeding a threshold indicative of insertion site loss or other loss of effectiveness.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a patient involves obtaining, by a control system associated with the infusion device, user input indicating an activity by the patient, obtaining historical data for the patient corresponding to the activity, determining a probable patient response corresponding to the activity based at least in part on the historical data for the patient, determining an adjustment for delivering the fluid by the infusion device based at least in part on the probable patient response, and operating the infusion device to deliver the fluid to the patient in accordance with the adjustment.