Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: The present invention provides pharmaceutical formulations for anti-IL-17 antibodies. These anti-IL-17 antibody pharmaceutical formulations can be used to treat rheumatoid arthritis, psoriasis, ankylosing psoriatic arthritis or multiple myeloma.

Abstract: The present invention provides stabilized pharmaceutical formulations for anti-IL-17 antibodies, comprising e.g. citrate, sodium chloride and polysorbate-80 at pH 5.7. These stabilized anti-IL-17 antibody pharmaceutical formulations can be used to treat rheumatoid arthritis, psoriasis, ankylosing spondilitis, psoriatic arthritis or multiple myeloma.

Abstract: The present teachings generally include a composite rotor assembly comprising a shaft and a rotor body mounted to the shaft. The rotor body can include a core structure including a cured polymeric material wholly or partly defining plurality of lobes joined by adjacent root portions. The rotor body can also include a support structure continuously extending the length of the core structure to provide additional structural integrity to the rotor body. The support structure can be wholly or partially embedded within the core structure and can also be wrapped around the exterior of the core structure. In one example, the core structure includes an epoxy resin and the support structure includes a carbon fiber material.

Abstract: A net-shaped composite plenum housing body for a differential assembly having a pump is disclosed. The plenum housing body can include a low pressure inlet and a high pressure outlet configured to receive a control valve. The plenum housing body can also define a fluid inlet channel in fluid communication with the low pressure inlet via a first internal port and can be configured to be in fluid communication with an inlet side of the pump when the plenum housing body is assembled onto the differential assembly. The plenum housing body can also define a fluid outlet channel in fluid communication with the high pressure outlet via a second internal port and can be configured to be in fluid communication with an outlet side of the pump when the plenum housing body is assembled onto the differential assembly. The plenum housing body can also be formed as a net-shape fiber reinforced plastic material including chopped fibers, for example, chopped fiberglass fibers, and an epoxy resin.

Abstract: The present teachings generally include a rotor assembly having a plurality of rotor sheets or layers mounted to a shaft, and methods of construction for a rotor assembly. Each rotor sheet or layer in the assembly may be provided with a central opening extending between the first and second sides through which the shaft extends. In one aspect, the rotor sheets or layers can be provided with a plurality of lobes extending away from the central opening, wherein each of the lobes can have a lobe opening extending through the thickness of the sheets or layers. In one example, the rotor sheets or layers can be rotationally stacked to form a helical rotor. In one example, the rotor sheets are formed from a pre-cured composite material and are bonded together with an adhesive.

Abstract: This invention relates to the detection and diagnosis of tuberculosis. More specifically, the invention relates to new biomarkers and combinations thereof that enable the accurate detection and diagnosis of tuberculosis.

Abstract: The present invention provides stabilized pharmaceutical formulations for anti-IL-17 antibodies, comprising e.g. citrate, sodium chloride and polysorbate-80 at pH 5.7. These stabilized anti-EL-17 antibody pharmaceutical formulations can be used to treat rheumatoid arthritis, psoriasis, ankylosing spondilitis, psoriatic arthritis or multiple myeloma.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: The present invention provides stabilized pharmaceutical formulations for anti-IL-17 antibodies, comprising e.g. citrate, sodium chloride and polysorbate-80 at pH 5.7. These stabilized anti-IL-17 antibody pharmaceutical formulations can be used to treat rheumatoid arthritis, psoriasis, ankylosing spondilitis, psoriatic arthritis or multiple myeloma.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: Improved hybrid construction and techniques for forming them are described. They are particularly applicable to generate load-bearing structures. Examples described include load-bearing housings. Methods of preparation, assembly and systems of methods of use are described.

Abstract: The present invention provides stabilized pharmaceutical formulations for anti-IL-17 antibodies, comprising e.g. citrate, sodium chloride and polysorbate-80 at pH 5.7. These stabilized anti-IL-17 antibody pharmaceutical formulations can be used to treat rheumatoid arthritis, psoriasis, ankylosing spondilitis, psoriatic arthritis or multiple myeloma.

Abstract: A method is provided for exchanging healthcare information between a plurality of healthcare providers.

Abstract: The present disclosure relates to a simplified roots-type blower having an improved sound signature. The roots-type blower includes a rotor bore housing having a molded, one-piece polymeric construction. The rotor bore housing defines a first rotor bore and a second rotor bore. The rotor bore housing also defines a first bearing pocket corresponding to the first rotor bore and a bearing pocket corresponding to the second rotor bore axis. The rotor bore housing further defining a timing gear chamber.

Abstract: A system is provided for employing an orchestrator to deploy and implement changes to a system. A change request may be a system build, upgrade, and patches for updating a subset of files within the system. The orchestrator may initially perform a security check and a validation check on a received change request. Upon receiving validation and approval, the change request may be deployed and propagated through a series of deployment scopes. The deployment scopes may become increasingly larger to extensively test the applied change before fully implementing the change on the target system. The orchestrator may submit the applied change to a validation component for getting validation of the change within the deployment scope after each applied change within a deployment scope. After the change request has been deployed through the deployment scopes and validated, the change request may be deployed to the target system and fully implemented.

Abstract: Bassinet assemblies and related methods are disclosed. An example bassinet assembly includes an upper frame, a first support arm and a second support arm coupled to the upper frame and a floorboard coupled or adjacent to the first support arm and the second support arm. The example bassinet assembly also includes a support liner coupled between the floorboard and the upper frame and a cover disposed over at least a portion of each of the upper frame, the support liner and the floorboard.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: This invention provides a cat scratching post with removable and/or interchangeable panels. The cat scratching post has a base, a column to house scratching panels, and a top cover. The top cover and the base are attached to the column by a nut and screw. The areas used for scratching may be exchanged as needed by simply removing the top and sliding the panel up and out and then turning it around to expose the other side. The panels may also be clipped together and attached to the column. Additional panels are stored inside the column. The panels may have different materials, colors and themes. The top cover serves a bed, which is removable for easy cleaning and is also reversible. There are also four corner pieces, which have hard plastic bumps so that the cat may rub and scratch its body. The corner pieces are also removable.