Patents by Inventor Anna Benedusi

Anna Benedusi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8883892
    Abstract: The present invention relates, in one aspect, to an adduct of formula O-PF-A, in which O is an oil; PF is a perfluoropolyether phosphate (PFPE phosphate); A is at least one substance selected from: (X) a water-soluble polyhydroxylated substance and (Y) a water-insoluble inorganic substance and to topical applications thereof in particular in the cosmetic and pharmaceutical field.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: November 11, 2014
    Assignee: Giuliani S.p.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Giovanni Pantini, Antonio Mascolo, Sergio Baroni
  • Patent number: 8729033
    Abstract: This invention regards the use of zeaxanthin and/or rutin, as such or further combined with spermidine, as the active principle in a pharmaceutical, dietary, or cosmetic composition, acting to inhibit caspase-3 and therefore to control apoptosis by preventing programmed cell death. The indication for this composition according to the invention is primarily the treatment of scalp disorders characterized by excessive cellular turnover including chemotherapy-induced alopecia, alopecia areata, androgenetic alopecia and telogen effluvium.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: May 20, 2014
    Assignee: Giuliani S.p.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni
  • Publication number: 20140065262
    Abstract: The present invention is directed to a method for preparing flour dough with reduced content of gluten starting from gluten containing cereals flours. In particular, the invention is directed to the use of lactic acid bacteria and fungal enzymes for the partial degradation of gluten in wheat flour in order to obtain flour dough with residual gluten concentration from 20,000-80,000 ppm. The flour dough obtained by the method of the invention can be used to prepare food products with reduced gluten content.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 6, 2014
    Applicant: GIULIANI S.p.A.
    Inventors: Giammaria GIULIANI, Anna Benedusi, Raffaella Di Cagno, Carlo Giuseppe Rizzello, Maria De Angelis, Marco Gobbetti, Angela Cassone
  • Publication number: 20140030207
    Abstract: The present invention relates to a system for the release of cosmetic agents comprising at least one phospholipid, hyaluronic acid or derivatives thereof and a cationic polyurethane derivative. The system of the invention may be used in the formulation of cosmetic preparations for obtaining the protracted release of cosmetic agents or active substances to the epidermis or the keratinic structures of the human body, with a simultaneous reduction in the frequency of application.
    Type: Application
    Filed: April 13, 2012
    Publication date: January 30, 2014
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni, Antonio Mascolo
  • Publication number: 20130231291
    Abstract: The present invention concerns a mixture comprising isoflavones-aglicones, such as daidzein, genistein and glycitein, in addition to equol and lunasin, said mixture being based on soya fermented using lactic acid bacteria isolated from food matrices and use of said mixture for protection of skin and similar and of human intestinal cells with particular reference to prevention of inflammatory state and protection of barrier functions and hair loss treatment.
    Type: Application
    Filed: July 11, 2011
    Publication date: September 5, 2013
    Inventors: Giammaria Giuliani, Anna Benedusi, Marco Gobbetti, Raffaella Di Cagno, Sergio Baroni, Carlo Giuseppe Rizzello
  • Publication number: 20130150443
    Abstract: The present invention relates to a novel use of compounds having the general formula (I): CH3(—CH?CH)n—R??(I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R?, CO—OR?, CO—O(-), where R? is chosen from among H, the alkyl from C1 to C22, each compound of general formula (I) being used as such or in a mixture, as an active principle in a pharmaceutical or cosmetic composition to improve the human epidermal cell repair activity by means of the production of keratin mediated by the cytokeratins cK-19.
    Type: Application
    Filed: February 6, 2013
    Publication date: June 13, 2013
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria GIULIANI, Anna BENEDUSI, Sergio BARONI
  • Publication number: 20130102712
    Abstract: The present invention relates, in one aspect, to an adduct of formula O-PF-A, in which O is an oil; PF is a perfluoropolyether phosphate (PFPE phosphate); A is at least one substance selected from: (X) a water-soluble polyhydroxylated substance and (Y) a water-insoluble inorganic substance and to topical applications thereof in particular in the cosmetic and pharmaceutical field.
    Type: Application
    Filed: June 23, 2011
    Publication date: April 25, 2013
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Giovanni Pantini, Antonio Mascolo, Sergio Baroni
  • Publication number: 20130059790
    Abstract: The present invention concerns a process for preparation of a biomass comprising one or a more plantaricins A, N or K in association with the lactic acid bacteria used for the preparation and uses thereof in order to stimulate the barrier function of intestinal cells or human epidermal keratinocytes.
    Type: Application
    Filed: January 4, 2011
    Publication date: March 7, 2013
    Applicant: GIULIANI S.p.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Marco Gobbetti, Raffaella Di Cagno, Maria De Angelis, Maria Calasso
  • Publication number: 20130046017
    Abstract: The invention relates to the use of compounds of general formula (I): CH3(—CH?CH)3—R??(I) wherein R is selected from CO—O—R? or CO—O(?), R? being selected from H, alkyl or alkenyl from C1 to C22, or sugars, and their pharmaceutically acceptable salts, preferably such as sodium, potassium, or lysine salts, each compound of general formula (I) being used as such or mixed with one or more of the others, as active ingredients in a pharmaceutical or cosmetic composition provided with antioxidant activity against free radicals.
    Type: Application
    Filed: April 22, 2011
    Publication date: February 21, 2013
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi
  • Patent number: 8178136
    Abstract: The present invention relates to preparations based on vegetal extracts of Ajuga reptans for favouring the growth of hair and stimulating the hair bulb. The preparations of the invention are in suitable formulations for oral administration or local application and are specifically suitable for the prevention and treatment of androgenic alopecia in males and females.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: May 15, 2012
    Assignee: Giuliani S.p.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Salvatore Bellinvia
  • Publication number: 20120093744
    Abstract: According to one aspect, the present invention relates to the use of a perfluoropolyether phosphate (PFPE phosphate), dissolved in water, for the preparation of oil-in-water emuisions (O/W) with high internal phase (HIPE). The internal phase (O) typically comprises at least 74% by volume of the emulsion and includes one or more OiIs1 which acquire, after a treatment with PFPE phosphate, some typical characteristics of high fluorine content compounds, in particular lipophobicity and homophobicity, combined with limited hydrophilicity.
    Type: Application
    Filed: July 10, 2009
    Publication date: April 19, 2012
    Inventors: Giammaria Giuliani, Giovanni Pantini, Antonio Mascolo, Anna Benedusi
  • Publication number: 20120034339
    Abstract: The present invention concerns the use of lactic acid bacteria selected and fungal enzymes for the gluten complete degradation from both bread and durum wheat, barley, rye and oat flour. In particular, the invention concerns the use of lactic acid bacteria selected and fungal enzymes for the gluten complete degradation (residual gluten concentration lower than 20 ppm) of cereal flours, which after detoxification can be used according to a standardized biotechnological protocol for the production of various gluten-free foods.
    Type: Application
    Filed: December 17, 2009
    Publication date: February 9, 2012
    Applicant: Giuliani S.p.A
    Inventors: Giammaria Giuliani, Anna Benedusi, Raffaella Di Cagno, Carlo Giuseppe Rizzello, Maria De Angelis, Marco Gobbetti, Angela Cassone
  • Publication number: 20120020902
    Abstract: The object of the invention is a mixture of catechin and quercetin in a molar ratio varying between 3:1 and 6:1, respectively, for the treatment of the immunosuppression induced in the skin by aggressive agents such as airborne pollutants, dehydrating agents, ultraviolet radiation, and thermal and osmotic shocks, and a pharmaceutical, dermatological, nutritional or cosmetic composition containing said mixture as an active ingredient.
    Type: Application
    Filed: April 30, 2010
    Publication date: January 26, 2012
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi
  • Publication number: 20120022282
    Abstract: The present invention concerns a process for synthesis of 2,4,6-octatriene-1-oic acid and 2,4,6-octatriene-1-ol, which comprises the following stages: a) reaction between 2,4-trans-hexadienal and triethyl phosphonoacetate to give ethyl 2,4,6-trans-octatrienoate; b) alkaline hydrolysis of ethyl 2,4,6-trans-octatrienoate to give the corresponding alkaline salt; c) acidification of said salt to give 2,4,6-trans-octatrienoic acid, which can be separated or can undergo the following further stages: d) reaction of the 2,4,6-trans-octatrienoic acid with ethyl chloroformiate to give the mixed anhydride formed by 2,4,6-trans-octatrienoic acid and ethyl carbonic acid; e) reduction of said mixed anhydride with sodium borohydride to give 2,4,6-trans-octatrienol; and optionally a purification stage of the end product.
    Type: Application
    Filed: April 16, 2010
    Publication date: January 26, 2012
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Aberto Milanese
  • Publication number: 20110224298
    Abstract: The present invention relates to a novel use of compounds having the general formula (I): CH3(—CH?CH)n—R??(I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R?, CO—OR?, CO—O(?), where R? is chosen from among H, the alkyl from C1 to C22, each compound of general formula (I) being used as such or in a mixture, as an active principle in a pharmaceutical or cosmetic composition to improve the human epidermal cell repair activity by means of the production of keratin mediated by the cytokeratins cK-19.
    Type: Application
    Filed: November 10, 2009
    Publication date: September 15, 2011
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni
  • Publication number: 20110218245
    Abstract: The object of the present invention is the use of compounds designed to inhibit the activity of the enzyme 5?-reductase. This is a novel use of compounds of general formula (I): CH3(—CH?CH)n—R??(I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R?, CO—O(?), where R? is chosen from among H, and the alky from C1 to C22, each compound of general formula (I) being used as such or in mixtures with other compounds, as the active principle in a pharmaceutical or cosmetic composition designed to inhibit the action of the enzyme 5?-reductase, and of the pharmaceutical or cosmetic compositions deriving therefrom.
    Type: Application
    Filed: November 10, 2009
    Publication date: September 8, 2011
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni
  • Publication number: 20110218164
    Abstract: This invention regards the use of zeaxanthin and/or rutin, as such or further combined with spermidine, as the active principle in a pharmaceutical, dietary, or cosmetic composition, acting to inhibit caspase-3 and therefore to control apoptosis by preventing programmed cell death. The indication for this composition according to the invention is primarily the treatment of scalp disorders characterized by excessive cellular turnover including chemotherapy-induced alopecia, alopecia areata, androgenetic alopecia and telogen effluvium.
    Type: Application
    Filed: October 30, 2009
    Publication date: September 8, 2011
    Applicant: Giuliani S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni
  • Publication number: 20110020476
    Abstract: The present invention relates to preparations based on vegetal extracts of Ajuga reptans for favouring the growth of hair and stimulating the hair bulb. The preparations of the invention are in suitable formulations for oral administration or local application and are specifically suitable for the prevention and treatment of androgenic alopecia in males and females.
    Type: Application
    Filed: June 18, 2010
    Publication date: January 27, 2011
    Inventors: Giammaria Giuliani, Anna Benedusi, Salvatore Bellinvia
  • Publication number: 20110015143
    Abstract: The present invention relates to the use of an agent to combat and reduce the irritating action of primary surfactants in compositions to be applied to the skin for care or cleansing of the face and body, characterized in that said agent is chosen from Cone or more salts of glycyrrhizic acid, such as monoammonium glycyrrhizinate (MAG) and dipotassium glycyrrhizinate (DPG).
    Type: Application
    Filed: March 13, 2009
    Publication date: January 20, 2011
    Applicant: GUULIANI S.P..A.
    Inventors: Antonio Mascolo, Anna Benedusi, Giammaria Giuliani
  • Publication number: 20100254948
    Abstract: This invention relates to a process for the production of gamma-aminobutyric acid (GABA) from Lactococcus lactis ssp. DSM 19464 and from Lactobacillus plantarum DSM 19463 or from their associations on must. In particular, this invention contemplates the selection and use of Lactococcus lactis ssp. DSM 19464 and of Lactobacillus plantarum DSM 19463 or their associations on must whose composition has been suitably optimized as to its composition, for the production of a preparation based on GABA, containing also vitamins, minerals, polyphenols and alive vital lactic bacteria for its potential use in the dermatological field.
    Type: Application
    Filed: July 17, 2008
    Publication date: October 7, 2010
    Applicant: Giuliani S.p.A
    Inventors: Giammaria Giuliani, Anna Benedusi, Raffaella Di Cagno, Carlo Giuseppe Rizzello, Maria De Angelis, Francesco Mazzacane, Marco Gobbetti