Patents by Inventor Anna Borodovsky

Anna Borodovsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS
    Publication number: 20110097720
    Abstract: The invention features a method of identifying therapeutically relevant compositions which include a therapeutic agent and 2,2-Dilinoley 1-4-dimethylaminomethyl-[1,3]-dioxolane by screening for an effect of the agent on the liver of a model subject.
    Type: Application
    Filed: December 31, 2008
    Publication date: April 28, 2011
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Marco A. Ciufolini, Thomas D. Madden, Michael J. Hope, Barbara Mui, De Fougerolles Antonin, Tatiana Novobrantseva, Anna Borodovsky, Akin Akinc, Mark Tracy, Pieter Rutter Cullis
  • Compositions And Methods For Inhibiting Expression Of A Gene From The Ebola Virus
    Publication number: 20110060031
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
    Type: Application
    Filed: May 27, 2010
    Publication date: March 10, 2011
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: Sina Bavari, Kelly Lyn Warfield, Pamela Tan, Anna Borodovsky, Tatiana Novobrantseva, Antonin de Fougerolles
  • LIVER SCREENING METHOD
    Publication number: 20110045473
    Abstract: The invention features a method of identifying therapeutically relevant compositions that include a therapeutic agent and a delivery component by screening for an effect of the agent on the liver of a model subject.
    Type: Application
    Filed: December 31, 2008
    Publication date: February 24, 2011
    Inventors: Antonin De Fougerolles, Tatiana Novobrantseva, Anna Borodovsky, Akin Akinc, Mark Tracy
  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD45 GENE
    Publication number: 20110034537
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the CD45 gene.
    Type: Application
    Filed: February 12, 2009
    Publication date: February 10, 2011
    Inventors: Antonin De Fougerolles, Pamela Tan, Anna Borodovsky, Tatiana Novobrantseva, Sina Bavari, Kelly Lyn Warfield
  • Compositions and methods for inhibiting expression of a gene from the Ebola
    Patent number: 7759320
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: July 20, 2010
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Sina Bavari, Kelly Lyn Warfield, Pamela Tan, Anna Borodovsky, Tatiana Novobrantseva, Antonin de Fougerolles
  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF A GENE FROM THE EBOLA
    Publication number: 20090143323
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
    Type: Application
    Filed: March 25, 2008
    Publication date: June 4, 2009
    Applicants: ALNYLAM PHARMACEUTICALS, INC., GOVERNMENT OF THE UNITED STATES
    Inventors: Sina Bavari, Kelly Lyn Warfield, Pamela Tan, Anna Borodovsky, Tatiana Novobrantseva, Antonin de Fougerolles
  • Semisynthetic protein-based site-directed probes for identification and inhibition of active sites, and methods therefor
    Publication number: 20050277762
    Abstract: A C-terminally modified Ubiquitin (Ub) derivative) ubiquitin vinyl sulfone (UbVS), which is specific for deubiquitinating enzymes (DUBs), was synthesized as an active site directed probe that irreversibly modifies a subset of Ub C-terminal hydrolases (UCHs) and Ub specific processing proteases (UBPs), is provided. [125I]-UbVS modifies 6 of the 17 known and putative yeast deubiquitinating enzymes, namely Yuh1p, Ubp1p, Ubp2p, Ubp6p, Ubp12p and Ubp15p. In mammalian cells, a greater number of polypeptides is labeled, most of which are DUBs. An additional DUB that associates with the mammalian 26S proteasome, novel protein USP14, a mammalian homolog of yeast Ubp6p that is bound to the proteasome, is provided.
    Type: Application
    Filed: April 25, 2003
    Publication date: December 15, 2005
    Inventors: Hidde Ploegh, Huib Ovaa, Anna Borodovsky, Benedikt Kessler, Joris Hemelaar, Paul Galardy, Nagamalleswari Kolli, Tudevin Gan-Erdene, Keith Wilkinson