Patents by Inventor Anthony E. Winston
Anthony E. Winston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6303104Abstract: An oral product, preferably a toothpaste, effective for remineralizing subsurface dental lesions, mineralizing exposed dentinal tubules and whitening teeth stained with discoloring residues containing heavy metal ions such as Fe+3, Mn+2 and Cu+2, is composed of a first discrete part composed of a water-soluble or partially water-soluble calcium salt and optionally a non-toxic, non-calcium water-soluble divalent metal salt, and a second discrete part composed of a water-soluble orthophosphate salt and preferably a water-soluble fluoride salt. Further enhanced stain-removing properties without excessive abrasivity are imparted to the oral product when part (A) further contains an effective amount of an anhydrous dicalcium phosphate abrasive and part (B) further contains an effective amount of a silica abrasive.Type: GrantFiled: February 12, 1999Date of Patent: October 16, 2001Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Jordan Barth, Norman Usen
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Patent number: 6159449Abstract: A dentifrice product substantially free of water-soluble inorganic orthophosphates and capable of remineralizing subsurface lesions and/or mineralizing exposed dentinal tubules in teeth, contains (A) a discrete cationic part containing at least one water-soluble and/or partially water-soluble calcium compound and a fluoride-protecting amount of at least one water-soluble and/or partially water-soluble magnesium compound, and (B) a discrete anionic part containing at least one water-soluble fluoride compound. The cationic and anionic parts are disposed separate from one another in the product and are simultaneously releasable from the product. The cationic and anionic parts each have a pH in water such that a mixed aqueous composition formed by mixing the cationic and anionic parts with (i) saliva or (ii) water and saliva has a pH of from about 4.0 to about 10.0. The mixed aqueous composition simultaneously applies the cationic and anionic parts to the tooth surfaces being treated.Type: GrantFiled: April 3, 1997Date of Patent: December 12, 2000Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 6159448Abstract: Improved one-part and two-part liquid products such as, e.g., mouthwashes, mouthrinses, toothpastes, gels and the like, for remineralizing subsurface lesions and/or mineralizing exposed dentin tubules in teeth contain a cationic component, an anionic component and a separating means for separating the cationic and anionic components. The anionic component contains water-soluble phosphate and fluoride salts, while the cationic component contains at least one partially water-soluble calcium salt and preferably at least one water-soluble salt of a divalent metal other than calcium. The tooth is treated with a mixed aqueous composition formed by mixing the cationic and anionic components with water and/or saliva. The mixed aqueous composition has a pH of from about 4.0 to about 10.0 and, in addition to dissolved calcium cations and dissolved phosphate and fluoride anions, contains a quantity of undissolved calcium salt.Type: GrantFiled: September 27, 1996Date of Patent: December 12, 2000Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 6036944Abstract: A method for remineralizing one or more subsurface lesions in a tooth and/or mineralizing one or more exposed dentinal tubules in the tooth involves dispensing effective amounts of at least one water-soluble calcium salt, at least one water-soluble non-toxic divalent metal compound wherein the divalent metal is other than calcium, at least one water-soluble phosphate salt and, optionally, a water-soluble fluoride salt; mixing the salts and compound to form a non-carbonated mixture having a pH in water such that a non-carbonated aqueous solution containing the mixture has a pH of from 4.5 to about 7.Type: GrantFiled: April 29, 1999Date of Patent: March 14, 2000Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5958380Abstract: This invention relates to a stable, single-part chewing gum product and methods of using same to effect remineralization of subsurface lesions in teeth and/or mineralization of exposed dentinal tubules. The chewing gum product contains a water-soluble cationic portion, a water-soluble anionic portion and a stabilizing component which substantially inhibits reaction between the cationic and anionic portions during storage of the chewing gum product but which allows the cationic and anionic portions to be simultaneously released at a substantially equal rate from the product when the product is chewed in the presence of saliva and/or water. The cationic portion is composed of at least one water-soluble calcium salt, and the anionic portion contains at least one water-soluble phosphate and, optionally, at least one water-soluble fluoride salt.Type: GrantFiled: July 7, 1997Date of Patent: September 28, 1999Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5939357Abstract: This invention provides a novel fungicide composition which has a bicarbonate-containing inorganic salt ingredient which enhances the efficacy of a fungicide ingredient for the treatment of cultivated crops. An invention fungicide composition also contains a surfactant ingredient, and a water-soluble organic compound which functions as a compatibility enhancing ingredient in aqueous formulations, and the ingredients improve the spreadability and adhesiveness of the composition when applied to foliage. An invention fungicide composition also contains a fertilizer-effective ratio of nitrogen, phosphorus and potassium.Type: GrantFiled: June 7, 1993Date of Patent: August 17, 1999Assignee: Church & Dwight Co., Inc.Inventors: Keith A. Jones, Anthony E. Winston, M. Stephen Lajoie, Amy L. Joseph
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Patent number: 5910323Abstract: This invention provides a novel aqueous pesticide formulation having a fungicidal bicarbonate-containing inorganic salt ingredient which enhances the efficacy of an insecticidal ingredient for treatment of cultivated crops. An invention pesticide formulation also contains a water-soluble organic compound which functions as a compatibility enhancing ingredient in the aqueous pesticide formulation, and improves the spreadability and adhesiveness of the composition ingredients when applied to foliage.Type: GrantFiled: October 21, 1993Date of Patent: June 8, 1999Assignee: Church & Dwight Co., Inc.Inventors: M. Stephen Lajoie, Amy L. Joseph, Keith A. Jones, Anthony E. Winston
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Patent number: 5895641Abstract: The present invention relates to the problems of remineralization without demineralization of dental enamel by applying to the teeth a composition which is present in two phases which do not react with one another until introduced into the oral cavity. One phase contains at least one water-soluble calcium compound and the other contains at least one water-soluble inorganic phosphate and at least one water-soluble fluorine compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent reaction causes rehardening of demineralized areas in the dental enamel.Type: GrantFiled: June 26, 1996Date of Patent: April 20, 1999Assignee: EnamelonInventors: Norman Usen, Anthony E. Winston
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Patent number: 5866102Abstract: This invention relates to non-aqueous compositions and methods utilizing same which are useful to remineralize subsurface dental enamel. More specifically, this invention relates to stable, single-part compositions containing calcium and phosphate salts which may be in a hydrophilic, non-aqueous vehicle and which when applied to lesions in dental enamel result in remineralization of subsurface dental enamel and/or mineralization of tubules in dentin thereby counteracting caries and/or hypersensitivity.Type: GrantFiled: January 21, 1997Date of Patent: February 2, 1999Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5860565Abstract: A planar, partition-forming insert member, when disposed in a tube, e.g., a toothpaste tube, divides the tube into two compartments for storage of two components which are to be prevented from reacting until the product is ready for use. A dual-compartment assembly contains the two separate compartments in which the two components are stored until the compartments are opened for use. The assembly contains a dispensing tube and the planar partition-forming insert member disposed in the tube, the insert member causing the tube to be divided into the two compartments. The assembly is capable of separately storing the components in the two compartments and simultaneously dispensing the components from the two compartments.Type: GrantFiled: May 13, 1997Date of Patent: January 19, 1999Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen, Linda J. Lancaster
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Patent number: 5858333Abstract: A two-part oral product capable of remineralizing subsurface lesions and/or mineralizing exposed dentinal tubules in teeth is composed of cationic and anionic discrete parts. The cationic discrete part contains at least one water-soluble calcium salt and, preferably, at least one non-toxic, water-soluble salt of a divalent metal other than calcium, and a first pharmaceutically acceptable carrier. The anionic discrete part contains at least one water-soluble phosphate salt and, preferably, at least one water-soluble fluoride salt, and a second pharmaceutically carrier. Preferably, one of the carriers is an aqueous carrier and the other of the carriers is a non-aqueous carrier. The cationic and anionic parts are simultaneously released from the product upon mixing of the product with water and/or saliva to form the mixed aqueous solution. In this way, calcium ions released by the calcium salt and phosphate ions released by the phosphate salt are simultaneously delivered to the tooth surfaces by the solution.Type: GrantFiled: August 7, 1998Date of Patent: January 12, 1999Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5833957Abstract: The present invention relates to remineralization, without demineralization, by applying to the teeth a composition which is present in either one or in two phases and which does not react to any large extent until introduced into the oral cavity and upon such introduction does not rapidly precipitate. One phase systems contain at least one water-soluble calcium compound, at least one other water-soluble, non-toxic compound containing a divalent metal different from calcium, and at least one water-soluble inorganic phosphate compound. If desired at least one water-soluble fluorine compound may be added to the system. In two phase systems one phase contains the calcium and the divalent metal compounds and the other the phosphate and optionally, the fluoride compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent, but controlled, reaction causes rehardening of demineralized areas in the dental enamel.Type: GrantFiled: August 27, 1997Date of Patent: November 10, 1998Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5817296Abstract: The present invention relates to remineralization, without demineralization, by applying to the teeth a composition which is present in either one or in two phases and which does not react to any large extent until introduced into the oral cavity and upon such introduction does not rapidly precipitate. One phase systems contain at least one water-soluble calcium compound, at least one other water-soluble, non-toxic compound containing a divalent metal different from calcium, and at least one water-soluble inorganic phosphate compound. If desired at least one water-soluble fluorine compound may be added to the system. In two phase systems one phase contains the calcium and the divalent metal compounds and the other the phosphate and optionally, the fluoride compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent, but controlled, reaction causes rehardening of demineralized areas in the dental enamel.Type: GrantFiled: May 29, 1997Date of Patent: October 6, 1998Assignee: Enamelon, Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5645840Abstract: This invention provides alkali metal bicarbonate powder consisting of a narrow size distribution range of ultrafine particles. The ultrafine powder has a large surface area, and provides enhanced reactivity in applications such as deodorization or neutralization, and exhibits increased antibacterial/antifungal activity. The ultrafine powder also has an exceptional capability to form a homogenous solid-phase suspension in a liquid medium which has long term stability.Type: GrantFiled: October 12, 1995Date of Patent: July 8, 1997Assignee: Church & Dwight Co., Inc.Inventors: M. Stephen Lajoie, Anthony E. Winston
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Patent number: 5645853Abstract: This invention relates to chewing gum compositions and methods utilizing same which are useful to remineralize subsurface dental enamel. More specifically, this invention relates to stable, single-part chewing gum compositions containing calcium and phosphate salts which when applied to lesions in dental enamel result in remineralization of subsurface dental enamel and/or mineralization of tubules in dentin thereby counteracting caries and/or hypersensitivity.Type: GrantFiled: August 8, 1995Date of Patent: July 8, 1997Assignee: Enamelon Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5628429Abstract: The present invention relates to plural compartment assemblies in which materials are stored in at least two separate compartments until the compartments are opened for use. More particularly, the invention relates to a dispensing tube whereby the utilization of a novel insert, a conventional dispensing tube can be divided into separate and discrete compartments at a low cost. The resulting dispensing assembly provides for dispensing more than one material from the same tube and even more particularly co-dispense predetermined proportions of incompatible materials simultaneously and effectively.Type: GrantFiled: November 22, 1995Date of Patent: May 13, 1997Assignee: Enamelon, Inc.Inventors: Norman Usen, Anthony E. Winston
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Patent number: 5605675Abstract: The present invention relates to the problems of remineralization, without demineralization of dental enamel by applying to the teeth a composition which is present in two phases which do not react with one another until introduced into the oral cavity. One phase contains at least one water-soluble calcium compound and the other contains at least one water-soluble inorganic phosphate and at least one water-soluble fluorine compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent reaction causes rehardening of demineralized areas in the dental enamel.Type: GrantFiled: June 6, 1995Date of Patent: February 25, 1997Assignee: Enamelon Inc.Inventors: Norman Usen, Anthony E. Winston
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Patent number: 5603922Abstract: The present invention relates to remineralization, without demineralization, by applying to the teeth a composition which is present in either one or in two phases and which does not react to any large extent until introduced into the oral cavity and upon such introduction does not rapidly precipitate. One phase systems contain at least one water-soluble calcium compound, at least one other water-soluble, non-toxic compound containing a divalent metal different from calcium, and at least one water-soluble inorganic phosphate compound. If desired at least one water-soluble fluorine compound may be added to the system. In two phase systems one phase contains the calcium and the divalent metal compounds and the other the phosphate and optionally, the fluoride compound. In this way the ions which effect remineralization can be absorbed by the dental enamel and their subsequent, but controlled, reaction causes rehardening of demineralized areas in the dental enamel.Type: GrantFiled: August 8, 1995Date of Patent: February 18, 1997Assignee: Enamelon Inc.Inventors: Anthony E. Winston, Norman Usen
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Patent number: 5583089Abstract: This invention provides a dry blend pesticide composition which contains a fungicidal bicarbonate salt ingredient, and a spreader-sticker ingredient which is a crystalline clathrate complex of a urea constituent and a normally liquid spreader sticker constituent such as a nonionic surfactant. In a preferred embodiment all of the composition ingredients are water-soluble, and the composition is readily dispersible in an aqueous medium to form a sprayable pesticide solution.Type: GrantFiled: May 9, 1995Date of Patent: December 10, 1996Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: RE36035Abstract: The present invention relates to plural compartment assemblies in which materials are stored in at least two separate compartments until the compartments are opened for use. More particularly, the invention relates to a dispensing tube whereby the utilization of a novel insert, a conventional dispensing tube can be divided into separate and discrete compartments at a low cost. The resulting dispensing assembly provides for dispensing more than one material from the same tube and even more particularly co-dispense predetermined proportions of incompatible materials simultaneously and effectively.Type: GrantFiled: November 7, 1997Date of Patent: January 12, 1999Assignee: Enamelon, Inc.Inventors: Norman Usen, Anthony E. Winston