Patents by Inventor Anthony J. Celeste
Anthony J. Celeste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7378392Abstract: Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.Type: GrantFiled: October 6, 1994Date of Patent: May 27, 2008Assignee: Genetics Institute, LLCInventors: Rodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
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Patent number: 7365052Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.Type: GrantFiled: June 17, 2005Date of Patent: April 29, 2008Assignees: Genetics Institute, LLC., President and Fellows of Harvard CollegeInventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
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Patent number: 7175997Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.Type: GrantFiled: July 5, 2002Date of Patent: February 13, 2007Assignee: Genetics Institute, L.L.C.Inventors: John M. Wozney, Anthony J. Celeste
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Patent number: 7151086Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: GrantFiled: August 26, 2002Date of Patent: December 19, 2006Assignee: Genetics Institute, LLCInventors: Anthony J. Celeste, Beth L. Murray
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Patent number: 7091007Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding the BMP receptor proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to the BMP receptor proteins.Type: GrantFiled: June 23, 2003Date of Patent: August 15, 2006Assignee: Genetics Institute, LLCInventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
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Patent number: 6984623Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.Type: GrantFiled: February 18, 2004Date of Patent: January 10, 2006Assignees: Genetics, Institute Institute, LLC., President and Fellows of Harvard CollegeInventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
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Publication number: 20040146923Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.Type: ApplicationFiled: February 18, 2004Publication date: July 29, 2004Applicants: Genetics Institute, LLC, President and Fellows of Harvard CollegeInventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
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Publication number: 20040142417Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.Type: ApplicationFiled: June 23, 2003Publication date: July 22, 2004Applicant: Genetics Institute, LLC.Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
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Patent number: 6719968Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.Type: GrantFiled: August 31, 2001Date of Patent: April 13, 2004Assignee: Genetics Institute, LLC.Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
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Patent number: 6623934Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: GrantFiled: November 26, 2001Date of Patent: September 23, 2003Assignee: Genetics Institute, LLC.Inventors: Anthony J. Celeste, Beth L. Murray
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Publication number: 20030166910Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.Type: ApplicationFiled: July 5, 2002Publication date: September 4, 2003Applicant: Genetics Institute, Inc.Inventors: John M. Wozney, Anthony J. Celeste
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Patent number: 6613744Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.Type: GrantFiled: March 23, 2001Date of Patent: September 2, 2003Assignee: Genetics Institute, LLCInventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
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Patent number: 6610513Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding these proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to these BMP receptor proteins.Type: GrantFiled: June 5, 2001Date of Patent: August 26, 2003Assignee: Genetics Institute, LLC.Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
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Publication number: 20030158379Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: ApplicationFiled: November 26, 2001Publication date: August 21, 2003Applicant: Genetics Institute, Inc.Inventors: Anthony J. Celeste, Beth L. Murray
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Publication number: 20030149241Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: ApplicationFiled: August 26, 2002Publication date: August 7, 2003Applicant: Genetics Institute, LLCInventors: Anthony J. Celeste, Beth L. Murray
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Publication number: 20030083252Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction and/or maintenance of bone, cartilage and/or other connective tissue, and/or neuronal tissue.Type: ApplicationFiled: December 20, 2001Publication date: May 1, 2003Applicant: Genetics Institute, Inc.Inventors: Anthony J. Celeste, John M. Wozney, R. Scott Thies
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Patent number: 6492493Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: GrantFiled: November 12, 1999Date of Patent: December 10, 2002Assignee: Genetics Institute, LLCInventors: Anthony J. Celeste, Beth L. Murray
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Publication number: 20020160494Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.Type: ApplicationFiled: August 31, 2001Publication date: October 31, 2002Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
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Publication number: 20020143159Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.Type: ApplicationFiled: November 12, 1999Publication date: October 3, 2002Inventors: ANTHONY J. CELESTE, BETH L. MURRAY
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Publication number: 20020137133Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.Type: ApplicationFiled: June 5, 2001Publication date: September 26, 2002Applicant: Genetics Institute, Inc.Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji