Patents by Inventor Anthony J. Celeste

Anthony J. Celeste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7378392
    Abstract: Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: May 27, 2008
    Assignee: Genetics Institute, LLC
    Inventors: Rodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
  • Patent number: 7365052
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: April 29, 2008
    Assignees: Genetics Institute, LLC., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Patent number: 7175997
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: February 13, 2007
    Assignee: Genetics Institute, L.L.C.
    Inventors: John M. Wozney, Anthony J. Celeste
  • Patent number: 7151086
    Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: August 26, 2002
    Date of Patent: December 19, 2006
    Assignee: Genetics Institute, LLC
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Patent number: 7091007
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding the BMP receptor proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to the BMP receptor proteins.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: August 15, 2006
    Assignee: Genetics Institute, LLC
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Patent number: 6984623
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: January 10, 2006
    Assignees: Genetics, Institute Institute, LLC., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Publication number: 20040146923
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Application
    Filed: February 18, 2004
    Publication date: July 29, 2004
    Applicants: Genetics Institute, LLC, President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Publication number: 20040142417
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Application
    Filed: June 23, 2003
    Publication date: July 22, 2004
    Applicant: Genetics Institute, LLC.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Patent number: 6719968
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: April 13, 2004
    Assignee: Genetics Institute, LLC.
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Patent number: 6623934
    Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: September 23, 2003
    Assignee: Genetics Institute, LLC.
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Publication number: 20030166910
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Application
    Filed: July 5, 2002
    Publication date: September 4, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste
  • Patent number: 6613744
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: September 2, 2003
    Assignee: Genetics Institute, LLC
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Patent number: 6610513
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding these proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to these BMP receptor proteins.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: August 26, 2003
    Assignee: Genetics Institute, LLC.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • Publication number: 20030158379
    Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Application
    Filed: November 26, 2001
    Publication date: August 21, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Publication number: 20030149241
    Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Application
    Filed: August 26, 2002
    Publication date: August 7, 2003
    Applicant: Genetics Institute, LLC
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Publication number: 20030083252
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction and/or maintenance of bone, cartilage and/or other connective tissue, and/or neuronal tissue.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 1, 2003
    Applicant: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, R. Scott Thies
  • Patent number: 6492493
    Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: December 10, 2002
    Assignee: Genetics Institute, LLC
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Publication number: 20020160494
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Application
    Filed: August 31, 2001
    Publication date: October 31, 2002
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Publication number: 20020143159
    Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Application
    Filed: November 12, 1999
    Publication date: October 3, 2002
    Inventors: ANTHONY J. CELESTE, BETH L. MURRAY
  • Publication number: 20020137133
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Application
    Filed: June 5, 2001
    Publication date: September 26, 2002
    Applicant: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji