Patents by Inventor Anthony J. Celeste

Anthony J. Celeste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bone morphogenetic protein-11 (BMP-11) compositions
    Patent number: 6437111
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: August 20, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste
  • BMP-6 proteins
    Publication number: 20020061577
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Application
    Filed: March 23, 2001
    Publication date: May 23, 2002
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Neuronal uses of BMP-11
    Patent number: 6340668
    Abstract: Purified BMP-11 proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction and/or maintenance of bone, cartilage and/or other connective tissue, and/or neuronal tissue.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: January 22, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, R. Scott Thies
  • Bone morphogenic protein-16 (BMP-16) compositions
    Patent number: 6331612
    Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: December 18, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, Beth L. Murray
  • BMP receptor proteins
    Patent number: 6291206
    Abstract: Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding said proteins and methods of using the receptor proteins. Further disclosed are truncated BMP receptor proteins and molecules which act as ligands to said BMP receptor proteins.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: September 18, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste, R. Scott Thies, Noboru Yamaji
  • BMP-9 compositions
    Patent number: 6287816
    Abstract: Purified bone morphogenetic protein-9 (BMP-9) proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: September 11, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Vicki A. Rosen, John M. Wozney, Anthony J. Celeste, R. Scott Thies, Jeffrey R. Song
  • Tendon-inducing compositions
    Patent number: 6284872
    Abstract: Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related tissue repair.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: September 4, 2001
    Assignees: Genetics Institute, Inc., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • BMP-6 proteins
    Patent number: 6207813
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: March 27, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • BMP-15 compositions
    Patent number: 6034229
    Abstract: Purified BMP-15-related proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-15-related proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage and/or other connective tissue defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: March 7, 2000
    Assignees: Genetics Institute, Inc., Vanderbilt University
    Inventors: Anthony J. Celeste, Jennifer L. Dube, Karen M. Lyons, Brigid Hogan
  • BMP-9 compositions
    Patent number: 6034061
    Abstract: Purified Bone Morphogenetic Protein (BMP)-9 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair, and in hepatic growth and function.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: March 7, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Vicki A. Rosen, John M. Wozney, Anthony J. Celeste, Scott R. Thies, Jeffrey R. Song
  • Bone morphogenetic protein (BMP)-17 and BMP-18 compositions
    Patent number: 6027917
    Abstract: Purified BMP-17 and BMP-18 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-17 and BMP-18 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, epithelium, brain, spleen, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: February 22, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, Beth L. Murray
  • BMP-12 and BMP-13 proteins and DNA encoding them
    Patent number: 6027919
    Abstract: The present invention relates to a novel family of purified proteins, and compositions containing such proteins, which compositions are useful for the induction of tendon/ligament-like tissue formation, wound healing and ligament and other tissue repair. The present invention further relates to DNA molecules, vectors and host cells useful for production of such proteins.
    Type: Grant
    Filed: November 2, 1994
    Date of Patent: February 22, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
    Patent number: 5965403
    Abstract: Purified BMP-16 proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-16 proteins are also disclosed. The proteins may be used in the treatment of bone, cartilage, other connective tissue defects and disorders, including tendon, ligament and meniscus, in wound healing and related tissue repair, as well as for treatment of disorders and defects to tissues which include epidermis, nerve, muscle, including cardiac muscle, and other tissues and wounds, and organs such as liver, lung, cardiac, pancreas and kidney tissue. The proteins may also be useful for the induction of growth and/or differentiation of undifferentiated embryonic and stem cells.
    Type: Grant
    Filed: September 18, 1996
    Date of Patent: October 12, 1999
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, Beth L. Murray
  • Antibodies to bone morphogenetic protein-10 (BMP-10)
    Patent number: 5932216
    Abstract: Purified Bone Morphogenetic Protein-10(BMP-10) proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-10 proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: August 3, 1999
    Inventors: Anthony J. Celeste, John M. Wozney
  • Bone morphogenetic protein (BMP)--6
    Patent number: 5849880
    Abstract: Purified bone morphogenetic protein (BMP)-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 15, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • BMP-15 compositions
    Patent number: 5728679
    Abstract: Purified BMP-15-related proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-15-related proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage and/or other connective tissue defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: March 17, 1998
    Assignees: Genetics Institute, Inc., Vanderbilt University
    Inventors: Anthony J. Celeste, Jennifer L. Dube, Karen M. Lyons, Brigid Hogan
  • Bone morphogenetic protein-10 (BMP-10) compositions
    Patent number: 5703043
    Abstract: Purified Bone Morphogenetic Protein-10 (BMP-10) proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-10 proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 30, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney
  • Bone morphogenetic protein -11 (BMP-11) compositions
    Patent number: 5700911
    Abstract: Purified Bone Morphogenetic Protein-11(BMP-11) proteins and processes for producing them are disclosed. Recombinant DNA molecules encoding the BMP-11 proteins are also disclosed. The proteins may be useful in regulating follicle stimulating hormone, such as for contraception. In addition, the proteins may be useful for the induction of bone, cartilage and/or other connective tissue.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: December 23, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste
  • DNA encoding and methods for producing BMP-8 proteins
    Patent number: 5688678
    Abstract: Purified cartilage and/or bone inductive proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 26, 1991
    Date of Patent: November 18, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Rodney M. Hewick, Jack H. Wang, John M. Wozney, Anthony J. Celeste
  • Bone morphogenetic protein-9 compositions
    Patent number: 5661007
    Abstract: Purified bone morphogenetic protein-9 (BMP-9) proteins and processes for producing them are disclosed, The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: April 22, 1993
    Date of Patent: August 26, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Anthony J. Celeste