Abstract: A semiconductor device includes a base layer including a silicon material. A field effect transistor is disposed on a first surface of the base layer. A first insulating interlayer covers the field effect transistor, A buried vertical rail passes through the first insulating interlayer and the base layer. The buried vertical rail includes a first metal pattern and a first barrier pattern surrounding a sidewall of the first metal pattern. A first lower insulating interlayer is on the second surface of the base layer. A lower contact plug passes through the first lower insulating interlayer and directly contacts a lower surface of the buried vertical rail. The lower contact plug includes a second metal pattern and a second barrier pattern surrounding a sidewall of the second metal pattern. A bottom surface of the first metal pattern and a top surface of the second metal pattern directly contact each other.

Abstract: A method for connecting at least two structural parts of an orthopedic component, wherein the structural parts are retained in an orienting device while oriented in relation to each other, and an intermediate space thus being formed between the structural parts. The orienting device and the structural parts together form a cavity, which has a flow connection to at least one feed connection, via which an adhesive for adhesively bonding the structural parts is introduced into the cavity.

Abstract: The present innovation is a customized compression device for prevention and treatment of keloids and hypertrophic scarring, primarily a frequent complication of ear piercing. The “one size fits all” design of traditional devices can compromise efficacy due to uneven fit and compression. This invention harnesses 3D digital scanning to capture the intricate contours of the ear for every patient, for personalized compression therapy. Using 3D printing, shells are fabricated with biocompatible materials such as Polylactic Acid, shape memory polymers, or silicone-based substances. In primary embodiments, device functionality is achieved with compression clips or spring-open, single-piece structures. The custom fit, potential for infusion of therapeutic agents (e.g., corticosteroids), and engineered porosity combine to improve keloid management from uniform pressure distribution and optimal healing. Additionally, the ‘shells’ can be pigmented to match patient skin tones and encourage compliance.

Abstract: Systems and methods of increasing paging opportunities when the unlicensed band is used are described. The gNB sends an RRC message that indicates multiple monitoring occasions in a paging occasion of a paging frame. The UE monitors a monitoring occasion of a PO to determine whether a PDCCH with a P-RNTI has been received in an unlicensed band. If such a PDCCH is received, the UE decodes PD SCH information in the PDCCH to determine whether the P-RNTI is a P-RNTI of the UE. If so, the UE avoids monitoring subsequent monitoring occasions of the PO. If the PDCCH does not contain a P-RNTI, the UE continues to monitor other monitoring occasions within the PO.

Abstract: Embodiments of a User Equipment (UE), Next Generation Node-B (gNB) and methods of communication are generally described herein. The UE may receive, from a gNB, configuration information related to a 2-step random access (RA) procedure between the UE and the gNB in unlicensed spectrum. The 2-step RA procedure may include: an uplink MsgA message that includes, within a random access occasion (RO), a MsgA preamble and a MsgA payload; and a downlink MsgB message that includes, within another RO, a MsgB PDCCH and a MsgB payload. The configuration information may indicate: resources allocated for the MsgA preamble; and a mapping between the resources allocated for the MsgA preamble and the MsgA payload. The UE may determine the resources allocated for the MsgA pay load based on the resources allocated for the MsgA preamble and the mapping.

Abstract: Embodiments of a User Equipment (UE), Next Generation Node-B (gNB) and methods of communication are generally described herein. The UE may receive, from a gNB, configuration information related to a 2-step random access (RA) procedure between the UE and the gNB in unlicensed spectrum. The 2-step RA procedure may include: an uplink MsgA message that includes, within a random access occasion (RO), a MsgA preamble and a MsgA payload; and a downlink MsgB message that includes, within another RO, a MsgB PDCCH and a MsgB payload. The configuration information may indicate: resources allocated for the MsgA preamble; and a mapping between the resources allocated for the MsgA preamble and the MsgA payload. The UE may determine the resources allocated for the MsgA payload based on the resources allocated for the MsgA preamble and the mapping.

Abstract: The gut-brain axis, neurobiology and neurotransmission are physiologic systems with known pathways, yet they are rarely leveraged for wellness, notwithstanding extensive literature regarding healthy diets and nutrition. Gastrointestinal (GI) evolution has equipped humans with exceptional plasticity for food abundance or scarcity, while maintaining homeostasis by producing essential neurotransmitters that drive fundamental behaviors, from seeking nourishment to engaging in routine tasks of life. The advent of cheap, abundant, and highly processed foods in the last century, however, has upended the very systems that evolved for survival with a debilitating propensity for obesity in abundance—and malnourishment where access may be limited to a scarce supply of such processed foods, or none at all. In short, a better understanding and application of physiologic signaling and equilibrium is needed in cases of weight management and malnourishment.

Abstract: The gut-brain axis, neurobiology and neurotransmission are physiologic systems with known pathways, yet they are rarely leveraged for wellness, notwithstanding extensive literature regarding healthy diets and nutrition. Gastrointestinal (GI) evolution has equipped humans with exceptional plasticity for food abundance or scarcity, while maintaining homeostasis by producing essential neurotransmitters that drive fundamental behaviors, from seeking nourishment to engaging in routine tasks of life. The advent of cheap, abundant, and highly processed foods in the last century, however, has upended the very systems that evolved for survival with a debilitating propensity for obesity in abundance—and malnourishment where access may be limited to a scarce supply of such processed foods, or none at all. In short, a better understanding and application of physiologic signaling and equilibrium is needed in cases of weight management and malnourishment.

Abstract: Disclosed are compositions and methods for directing NK cells to the bone marrow through the use of PM21 particles.

Abstract: According to various embodiments, a control method may be provided. The control method may include: determining geometric information about respective geometries of respective housings of a plurality of light sources; determining a photographic representation of an environment in which the plurality of light sources are provided; determining spatial information about the plurality of light sources based on the geometric information and based on the photographic representation; determining control information for the plurality of light sources based on the spatial information; and controlling the plurality of light sources based on the control information.

Abstract: An exercise with oxygen therapy (EWOT) apparatus for rejuvenating oxygen-depleted cell tissue and simulating high altitude oxygen conditions. The EWOT apparatus includes a first cylindrical bladder for providing oxygen-enriched air and a second bladder for providing lower-purity hypoxic air. The first bladder is retained within an open, lightweight rectangular-shaped frame having vertical frame members. An air supply source provides the oxygen-enriched and hypoxic air to the first and second bladders, respectively. A control switch, which can be manually and/or programmed to automatically operate, selectively delivers the oxygen-enriched and/or hypoxic air to a breathing mask worn by a user while exercising on exercise equipment. The first bladder includes a plurality of weights which provide a positive pressure to the air therein.

Abstract: Disclosed are compositions and methods for directing NK cells to the bone marrow through the use of PM21 particles.

Abstract: Disclosed herein are expanded NK cells and methods of using thereof for treating, preventing, reducing, and/or inhibiting a microbial infection.

Abstract: Disclosed are engineered feeder cells comprising soluble or membrane bound TGF-b and methods of their use in the production of NK cells resistant to TGF-b and use of said generated TGF-b resistant NK cells to treat a cancer.

Abstract: There are provided systems and methods for using a hierarchical vectoriser for representation of healthcare data. One such method includes: receiving the healthcare data; mapping the code type to a taxonomy and generating node embeddings using relationships in the taxonomy for each code type with a graph embedding model; generating an event embedding for each event including aggregating vectors associated with each parameter vector using a non-linear mapping to the node embeddings, the event embedding including the node embeddings related to said event; generating a patient embedding for each patient by encoding including the event embeddings related to said patient; and outputting the embedding for each patient.

Abstract: An acoustically insulated machine including a source of noise positioned within a housing, a first insulation member positioned within the housing and including a first porous sound absorbing layer and a first dense layer, and a second insulation member positioned within the housing and including a second porous sound absorbing layer and a second dense layer. The first insulation member being is positioned closer to the internal source of noise than the second insulation member and the first insulation member being spaced apart from the second insulation member such that an air gap is formed between the first insulation member and the second insulation member.