Abstract: Multi-angle radiographic imaging enables 3D visualization of internal surgical targets like solid-tumors, heart vessels, blocked glands or any bodily cavities like fallopian or Eustachian tubes for diagnostics and surgery planning. Those images are dimensionally precise and easily replicated as life-forms with 3D printing for exact modeling. The “negative” aspects of the images are the diseased tissues requiring excision, as in a solid-tumor example. Needle biopsies are routine and can be radiographically guided. Similarly, guided needle delivery of a magnetic surgical fluid containing fullerenes into a target site, such as a solid tumor is less invasive than laparoscopic techniques. Introducing an external magnetic field force can then be used to propel, rotate and maneuver fullerenes into cellular matter or into tissue.

Abstract: The present invention pertains to quantum-scale biocidal particles and chemical reactions that disrupt and eviscerate microbial matter by combining aqueous and dry components. As halo-fullerene activation requires volatile excitation to mix, contact and collide so as to rupture microbial matter, atomic scale chemical reactions impart the requisite movement of engineered halo-fullerenes to destroy bacterial, fungal and viral matter upon contact. The present invention includes two primary mechanisms: an excitation chemistry and biocidal, hydrophobic halo-fullerenes. Upon aqueous exposure, the dry composition initiates a chemical reaction that activates biocidal halo-fullerenes to disrupt biologic surfaces in topical applications. The object of the present invention is a shelf stable, pre-packaged wiping material or dry packet for rehydration with broad spectrum antimicrobial activity.

Abstract: A method for connecting at least two structural parts of an orthopedic component, wherein the structural parts are retained in an orienting device while oriented in relation to each other, and an intermediate space thus being formed between the structural parts. The orienting device and the structural parts together form a cavity, which has a flow connection to at least one feed connection, via which an adhesive for adhesively bonding the structural parts is introduced into the cavity.

Abstract: A network device (e.g., a user equipment (UE), or a new radio NB (gNB)) can process or generate a configuration of a physical random access channel (PRACH) over physical resource blocks (PRBs) that are interlaced in an unlicensed band in an NR unlicensed (NR-U) communication. The PRBs in the PRACH can be based on an occupied channel bandwidth (OCB) of the unlicensed band in the NR-U communication. A random access channel transmission in the PRACH can then be generated by interlacing the PRBs defining the PRACH.

Abstract: An acoustically insulated machine including a source of noise positioned within a housing, a first insulation member positioned within the housing and including a first porous sound absorbing layer and a first dense layer, and a second insulation member positioned within the housing and including a second porous sound absorbing layer and a second dense layer. The first insulation member being is positioned closer to the internal source of noise than the second insulation member and the first insulation member being spaced apart from the second insulation member such that an air gap is formed between the first insulation member and the second insulation member.

Abstract: Disclosed are genetically modified NK cells comprising a knockout of the cluster of differentiation 38 (CD38) gene and methods of using the same to treat a cancer including, but not limited to multiple myeloma, acute myeloid leukemia (AML), T-cell acute lymphoblastic leukemia (T-ALL), or Blastic plasmacytoid dendritic cell neoplasm (BPDCN).

Abstract: A composite fracturing tree includes an operating valve and a master valve in fluid communication with the operating valve. The master valve includes an inlet portion in fluid communication with the operating valve, an outlet portion, and a gate portion. The gate portion is disposed between the inlet portion and the outlet portion. The gate portion is moveable between a flow position and an occluding position. In the flow position, the gate portion permits flow between the inlet portion and the outlet portion. In the occluding position, the gate portion prevents flow from the inlet portion to the outlet portion. The gate portion is actuated from the flow position to the occluding position with a closing force and from the occluding position to the flow position with an opening force. The master valve allows for the closing force to reduced compared to conventional fracturing valves.

Abstract: Techniques described herein are directed to a scheduling platform configured to determine a time for scheduling a meeting. The scheduling platform receives a request for a new meeting and may associate the new meeting with available times on a calendar of a representative. The scheduling platform utilizes prediction model(s) to determine a probability of acceptance of an invitation to the meeting scheduled at each of the available times. Additionally, the scheduling platform may determine a joint probability of a multibook instance in which two or more invitations to meetings scheduled at a same time may be accepted. The scheduling platform selects the time for the new meeting based on the probability of acceptance and/or the joint probability of the multibook instance. The scheduling platform may deliver invitations that have a higher probability of acceptance in order to maximize a density of accepted meetings on a representative calendar.

Abstract: Disclosed are compositions and methods for measuring the likelihood of recovery of a recently thawed immune cell. Methods include assaying the level of an ADAM-17-cleaved surface receptor expressed on the immune cells, wherein the level of the surface receptor directly correlates with the likelihood of immune cell recovery (i.e., the greater the increase of the expression level an ADAM-17-cleaved surface receptor relative to a control, the greater the likelihood of recovery). The method can be used to determine if immune cells have sufficient viability to be used in immunotherapy before use.

Abstract: Tissue and organ transplantation success is chiefly dependent on the harvest and preservation techniques employed. Yield and quality enhancements are needed, because qualified patient demand far outpaces donors and ultimately, tissues and organs stored and transported so as to render them in acceptable condition for surgery. In the case of corneal transplants, tissue supplies help 1 out of 70 patients in need despite being among the most successful such procedures today. Transplant success has improved overall with enhanced storage and transport methods that have allowed for greater time and distances to reach patients in need, whether corneas, kidneys, hearts, lungs, livers or other tissues, limbs or cellular materials. While corneal tissues specifically benefit from oxygenation via direct air contact and normal tears in a healthy individual, once donated, the lack of corneal vascularization can uniquely accelerate the depletion of oxygen that occurs upon harvesting of all transplant materials.

Abstract: An apparatus, method and system for providing and dispensing various hand care alternatives from a common point of dispension, such as a faucet, for standardizing the hand care, washing, sanitizing, and drying process is disclosed. Included is a liquid flow path having an inlet in fluid communication with a liquid source and an outlet in fluid communication with a user reception point. A secondary flow path has an inlet in communication with one or more hand care alternatives and an outlet in communication with the user reception point. A user-perceivable output provides notification of the hand care operation being provided at the user reception point.

Abstract: Embodiments as disclosed include document analysis systems that may obtain email data collected or obtained from email servers from one or more source systems and build a graph of the emails, where the nodes of the email graph represent data about an email and the edges in the graph between the nodes of the graph are determined based on metadata associated with the emails or the text content of the emails. These email graphs may be quickly and efficiently updated as new email data is obtained such that the document analysis systems may organize emails into conversations for utilization by users in reviewing these emails in context.

Abstract: Machines or networked devices such as internet of things (IoT) devices operate to generate an unlicensed IoT (U-IoT) communication or enhanced Machine Type Communication (eMTC) based on frequency hopping operations on different channels. An anchor channel can be configured to carry system information and paging messages for the U-IoT/eMTC communication on the different channels. The system information and paging messages can include essential system information such as a system information block MulteFire (SIB-MF) message. Physical channels can be configured to enable component carriers anchored to a long term evolution (LTE) licensed band, and entirely comprise unlicensed carrier components that are unanchored to any LTE component carrier in a standalone configuration to enable transmission of the U-IoT communication in standalone communications in an unlicensed band.

Abstract: The invention relates to a debris retaining cover for retaining debris in the region of an undercarriage of a track-type vehicle. The cover includes a barrier member which provides a barrier to restrict egress of debris from the undercarriage of the vehicle and an attachment mechanism which is arranged to secure the barrier member across an undercarriage of the vehicle. A track-type vehicle provided with the debris retaining cover is also disclosed.

Abstract: Some embodiments of this disclosure include systems, apparatuses, methods, and computer-readable media for use in a wireless network for improving configured grant for new radio (NR) unlicensed. For example, some embodiments are directed to an electronic device including radio front end circuitry and processor circuitry. The processor circuitry can be configured to receive, using the radio front end circuitry, a message from a base station and, based on the received message, determine whether to use a lowest Channel Access Priority Class (CAPC) or a highest Units (SDUs) that are multiplexed in one or more MAC Protocol Data Units (PDUs) for an uplink (UL)transmission. The processor circuitry transmits, using the radio front end circuitry, the MAC PDU to the base station.

Abstract: Disclosed are methods for genetically engineering cells using Adeno-associated viral (AAV) delivery of a CRISPR/CAS9 system and ribonucleoproteins for integration.

Abstract: Disclosed are expanded NK cell compositions comprising, in some aspects, activated STAT3 transcriptomes and methods of using the same to treat, inhibit, reduce, ameliorate, and/or prevent diseases.

Abstract: The disclosure is directed to a system and method of operating a user equipment (UE) to make the new radio (NR) carrier aggregation more effective. The system and method can include at least: receiving a release message confirming release of the UE from a base station, the release message including Long Term Evolution radio access technology (RAT) frequencies and New Radio (NR) RAT frequencies; measuring during an IDLE state, the LTE RAT frequencies and the NR RAT frequencies; transmitting a resume request message to the base station, the resume request message including an indication of a measurement report available from the UE, the measurement report including frequency measurements for the LTE RAT frequencies and the NR RAT frequencies; and after a security setup with the base station, transmitting a resume complete message to the base station, the resume complete message including the measurement report with the LTE RAT frequency measurements and NR RAT frequency measurements.