Abstract: The invention refers to a handheld injection device comprising a housing (10; 340) containing a cartridge (20), a dose setting means (60, 70; 350) being operable in a first direction to set a desired dose to be dispensed, a piston rod (30) being adapted to cooperate with a piston so as to cause a set dose to be injected from the cartridge (20), and a first clicker component (100; 320), which is largely rotationally constrained to the housing (10; 340), and a second clicker component (80; 300), which is rotatable relative to the housing (10; 340) during dose dispensing. The clicker components (80, 100; 300, 320) are adapted to contact each other only at the end of dispensing of a set dose to thereby provide an audible and/or tactile first feedback to a user. The first clicker component (100; 320) is displaceable relative to the housing (10; 340) between a proximal dose setting position and a distal dose dispensing position.

Abstract: The invention refers to a handheld injection device comprising a housing (10; 210; 410), a piston rod (30; 230; 530), defining a first longitudinal axis (I) and located within the housing (10; 210; 410), a driver (40; 241, 242; 500) coupled to the piston rod (30; 230; 530), a dose setting means (60, 70), which is rotatable about a second longitudinal axis (II) during dose setting, and optionally a power reservoir (90; 290; 10) for driving the driver (40; 241, 242; 500) and/or a release clutch (15, 45; 300; 06) preventing rotation of the driver (40; 241, 242; 500) during dose setting and allowing rotation of the driver (40; 241, 242; 500) during dose dispensing. The first longitudinal axis (I) is spaced from the second longitudinal axis (II).

Abstract: The invention refers to a handheld injection device comprising a housing (10, 20, 30), a piston rod (60), defining a first longitudinal axis (I) and located within the housing (10), a driver (70, 80, 90) coupled to the piston rod (60), a dose setting means (40), which is rotatable during dose setting, a power reservoir (100) for driving the driver (70, 80, 90), and a number wheel (130) for displaying a dose set by the dose setting means (40).

Abstract: A display assembly for a drug delivery device (100) is provided. The display assembly comprises a housing (10) having a proximal end (17), a distal end (16) and a longitudinal axis (x). The display assembly further comprises a display member (120) defining a display member window (122), wherein the display member (120) is rotationally locked to but movable with respect to the housing (10) along the longitudinal axis (x). The display assembly further comprises an indication member (60) comprising indicia (66) and a movable member (110) which is rotationally coupled to the indication member (60). The movable member (110) is further coupled to the display member (120) and rotatable with respect to the housing (10). When the movable member (110) is rotated with respect to the housing (10), the rotating movable member (110) moves the display member (120) axially with respect to the housing (10) to display different indicia (66) through the display member window (122).

Abstract: The invention refers to a handheld injection device comprising a housing (10; 410) and a dose indicator (90; 480) positioned within and axially constrained to the housing (10; 410) and rotatable with respect to the housing (10; 410) during dose setting and during dose dispensing. The dose indicator (90; 480) may comprise a flexible clicker arm (95; 482) which, only during dispense, is displaced in a first radial direction and, when the device reaches its minimum dose (zero) position, in a second, opposite radial direction.

Abstract: The invention refers to a handheld injection device comprising a housing (10; 410), a dose indicator (90; 480) positioned within and axially constrained to the housing (10; 410) and rotatable with respect to the housing (10; 410) during dose setting and during dose dispensing, a gauge element (80; 490), which is at least partly interposed between the housing (10; 410) and the dose indicator (90; 480), wherein the gauge element (80; 490) is axially guided within the housing (10; 410) and in threaded engagement with the dose indicator (90; 480) such that rotation of the dose indicator (90; 480) causes an axial displacement of the gauge element (80; 490). A contrast element having a first marking is provided and at least a region of the gauge element (80; 490) is provided with a second marking, with the first marking and/or the second marking being visible through a first window (12a) or aperture in the housing (10; 410) depending on the axial position of the gauge element (80; 490) within the housing (10; 410).

Abstract: The present invention relates to a handheld injection device comprising a housing (10), a piston rod (130) located within the housing (10), a drive member (100) and a power reservoir (110) for driving the drive member (100). The drive member (100) is permanently coupled to the piston rod (130), with the drive member (100) being axially movable between a dose setting position, in which the drive member (100) is rotationally constrained to the housing (10), and a dose dispensing position, in which the drive member (100) is rotationally decoupled from the housing (10). The power reservoir (110) comprises a reverse wound flat spiral spring having a first end attached to a first spool (120) and a second end attached to a second spool, which is axially and rotationally constrained to drive member (100).

Abstract: The invention refers to an injection device comprising a housing (10) containing a cartridge (20) containing a medicament and a movable bung (21), wherein the housing (10) comprises an inner thread (17), a piston rod (30) for moving the bung (21) during dose dispensing, wherein the piston rod (30) comprises an outer thread (31) engaging the inner thread (17) of the housing (10) a bearing (33) at its end facing the bung (21), and a driver (40) coupled to the piston rod (30) for driving the piston rod (30) during dose dispensing. In the unused delivery state of the device, the bearing (33) abuts the bung (21). The invention further refers to an assembly method for such an injection device.

Abstract: The invention refers to a dispensing speed control mechanism for use in an injection device having a release button (71), which is displaceable to initiate dispensing of a set dose, a first component part (42), which is driven by a power reservoir (90) during dose dispensing, and a second component part (12), which is stationary during dose dispensing. The speed control mechanism comprises friction means (120) for retarding the first component part (42) during dose dispensing depending on the position of the release button (71). Further, the invention refers to a handheld injection device with such a speed control mechanism.

Abstract: A drive assembly for a drug delivery device (100) is provided. The drive assembly comprises a housing (10) having a proximal end (17) and a distal end (16) and a drive mechanism comprising a piston rod (30) and a drive member (40) to drive the piston rod (30) to dispense a dose of drug and a dose member (70) coupled to the drive member (40). The assembly further comprises a return mechanism comprising a spring member (130). The assembly further comprises a movable member (110) which is coupled to the spring member (130). In a setting mode of operation, the movable member (110) is coupled to the dose member (70) and, the movable member (110) is movable from an initial position to a dose set position, thereby biasing the spring member (130).

Abstract: The invention refers to a handheld injection device comprising a housing (10, 20, 30), a piston rod (60), defining a first longitudinal axis (I) and located within the housing (10), a driver (70, 80, 90) coupled to the piston rod (60), a dose setting means (40), which is rotatable during dose setting, a power reservoir (100) for driving the driver (70, 80, 90), and a number wheel (130) for displaying a dose set by the dose setting means (40).

Abstract: A drive mechanism of a drug delivery device and a respective drug delivery device for setting and dispensing of a dose of a medicament are presented, where the drive mechanism has an elongated housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge containing the medicament, a dosing arrangement manually and axially displaceable relative to the housing for setting and dispensing of the dose, and an accessory drive operably engaged with the piston rod to support a manually operated dose dispensing displacement of the dosing arrangement.

Abstract: A drug delivery device comprising: a housing; a plurality of sensors; and a cylindrical member supported within the housing, the outer surface of said cylindrical member being provided with a helical track, the helical track comprising track segments of a first type and track segments of a second type, the first and second types of track segment being respectively capable of inducing first and second responses in the sensors; wherein: the helical track has a width dimension W; the helical track includes across its width at least one track segment of the first type and at least one track segment of the second type at plural positions along the length of the helical track; the device is configured such that during a first phase of a drug delivery operation the helical track is moved axially, without rotation, relative to the plurality of sensors between a first position and a second position, and during a second phase of the drug delivery operation the track is moved helically relative to the plurality of senso

Abstract: A drug delivery device, comprises a housing having a longitudinal axis; an axially moveable component that is moveable along the longitudinal axis between a dose dialing position and a dose delivery position when a user operates the device to deliver a dose of drug; an encoder sleeve; an encoder pattern provided on the encoder sleeve, the encoder pattern comprising relatively conductive portions and relatively non-conductive portions that together comprise coded information; a contact-supporting component; and plural electrical contacts provided on the contact-supporting component. The plural electrical contacts contact the encoder pattern when the dose delivery button is in the dose dialing position and wherein the device is configured to move the contact-supporting component relative to the encoder sleeve as the axially moveable component moves from the dose dialing position to the dose delivery position such as to move the electrical contacts into positions where they do not contact the encoder pattern.

Abstract: A method of decoding encoded information is presented where one or more sensors are controlled to periodically check for motion of a movable component of a drug delivery device having encoded information thereon. If motion of the movable component is detected, preventing a first encoded information reading and decoding process from being performed, when motion of the movable component is not detected, performing the first encoded information reading and decoding process.

Abstract: The invention relates to an arrangement for detecting a position of a plunger relative to a bung in a drug cartridge, comprising a proximity sensor located close to a distal end of the plunger facing the bung and aligned to receive light reflected by the bung.

Abstract: A system for identifying users and controlling access to a radiotherapy apparatus, comprising: a portable identification device, comprising a memory for storing identification information corresponding to a user of the device and an antenna; and a control mechanism for a radiotherapy apparatus, comprising: a wireless transceiver for communicating with the portable identification device and identifying the user of the portable identification device; and a display for displaying a user interface and receiving inputs for controlling the radiotherapy apparatus on the basis of the identified user when the portable identification device is placed on the display.

Abstract: A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with at least first and second tracks together forming an encoder, each track comprising conductive segments and non-conductive segments; and at least first and second groups of contacts configured to engage the first and second tracks respectively at predetermined intervals along the length of the track.