Patents by Inventor Antonio Caiafa
Antonio Caiafa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10421956Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.Type: GrantFiled: April 17, 2018Date of Patent: September 24, 2019Assignee: GENERAL ELECTRIC COMPANYInventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
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Publication number: 20190264160Abstract: Disclosed herein are multi-cuvette cartridges, flow cells, and electrical pulse systems for treatment of large volumes of biological samples with pulsed electric fields. The multi-cuvette cartridges systems may include mechanical motors for automatic positioning and alignment between the cuvettes and the electrodes of the electrical pulse systems. The flow cell systems may include fluidic systems, such as pumps, nozzles and valves, which may operate in coordination with the electrical systems for efficient exposition of biological samples. Embodiments having flow cell systems that allow “on-demand” production of activated sample are also disclosed.Type: ApplicationFiled: February 26, 2018Publication date: August 29, 2019Inventors: Antonio Caiafa, Vasile Bogdan Neculaes
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Patent number: 10383915Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.Type: GrantFiled: August 30, 2016Date of Patent: August 20, 2019Assignee: GENERAL ELECTRIC COMPANYInventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
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Patent number: 10369200Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.Type: GrantFiled: August 30, 2016Date of Patent: August 6, 2019Assignee: GENERAL ELECTRIC COMPANYInventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
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Patent number: 10329551Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.Type: GrantFiled: July 17, 2017Date of Patent: June 25, 2019Assignee: GENERAL ELECTRIC COMPANYInventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
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Publication number: 20190181857Abstract: A gate drive circuit device includes positive and negative pulse circuit portions each including a pulse diode and a pulse assembly connected in parallel with each other. The pulse assemblies each include another pulse diode and a resistor-capacitor assembly connected in series. The resistor-capacitor assembly includes a pulse resistor and a pulse capacitor connected in parallel. Each pulse circuit portion is connected with a different switch. Each pulse circuit portion is a passive device that is configured to activate a different switch responsive to receiving one or more voltage pulses from a power supply.Type: ApplicationFiled: September 4, 2018Publication date: June 13, 2019Inventors: Antonio Caiafa, Dominique Poincloux, Marcos Garcia Arregui
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Patent number: 10290460Abstract: An X-ray tube is provided. The X-ray tube includes an electron beam source including a cathode configured to emit an electron beam. The X-ray tube also includes an anode assembly including an anode configured to receive the electron beam and to emit X-rays when impacted by the electron beam. The X-ray tube further includes a gridding electrode disposed about a path of the electron beam between the electron beam source and the anode assembly. The gridding electrode, when powered at a specific level, is configured to grid the electron beam in synchronization with planned transitions during a dynamic focal spot mode.Type: GrantFiled: September 7, 2016Date of Patent: May 14, 2019Assignee: GENERAL ELECTRIC COMPANYInventors: Michael John Utschig, Uwe Wiedmann, Bruno Kristiaan Bernard De Man, Sergio Lemaitre, Mark Alan Frontera, Antonio Caiafa, Jiahua Fan, Adam Budde
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Patent number: 10262829Abstract: A circuit assembly and method use a breakover device that changes states in response to a change in electric energy in a helper circuit that supplies current from a power source to a powered system. The helper circuit includes an inductive element connected with the powered system. The breakover device is in a non-conducting state prior to a discharge event from the powered system to prevent the current from the power source from being conducted through the resistive element. The breakover device changes to a conducting state responsive to the powered system discharging current into the helper circuit. The breakover device conducts the current that is discharged from the powered system through the resistive element to reduce the electric energy in the helper circuit from the current that is discharged.Type: GrantFiled: August 26, 2016Date of Patent: April 16, 2019Assignee: General Electric CompanyInventors: Antonio Caiafa, Phillipe Ernest, Dominique Poincloux, Uwe Wiedmann, Denis Perrillat-Amee
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Patent number: 10250156Abstract: A cryogenic fuel power system includes an engine. The cryogenic fuel power system includes a cryogenic fuel supply that supplies cryogenic fuel to be used as fuel by the engine. The cryogenic fuel power system includes a cryogenic bus configured to provide the cryogenic fuel from the cryogenic fuel supply to the engine. The cryogenic fuel power system includes power electronics circuitry that converts power from the engine into a form to be applied to one or more loads. The power electronics circuitry is positioned in thermal communication with the cryogenic bus to transfer heat from the power electronics circuitry to the cryogenic fuel.Type: GrantFiled: January 5, 2017Date of Patent: April 2, 2019Assignee: General Electric CompanyInventor: Antonio Caiafa
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Patent number: 10205379Abstract: A power system includes a first unit block having first resonant circuitry that receives power from a DC bus, a first controlled rectifier that provides a first portion of power to one or more loads at a first voltage level, and a first transformer coupled between the first resonant circuitry and the first controlled rectifier. A second unit block includes second resonant circuitry that receives power from the DC bus, a second controlled rectifier configured to provide a second portion of power to the one or more loads at a second voltage level, and a second transformer coupled between the resonant circuitry and the controlled rectifier. The first and second unit blocks are coupled in series to output a summation waveform.Type: GrantFiled: January 5, 2017Date of Patent: February 12, 2019Assignee: GENERAL ELECTRIC COMPANYInventor: Antonio Caiafa
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Patent number: 10129973Abstract: A voltage divider circuit assembly includes resistors, an external electrostatic shield, and internal electrostatic shield(s). The resistors are in series with each other between input terminals that receive an input voltage. An external resistor is disposed between sensing terminals that conduct an output voltage that is the input voltage divided by the resistors in the series. The external shield is conductively coupled with the series of the resistors with the external resistor disposed outside of the external shield and the other resistor(s) inside the external shield. The internal shield(s) are conductively coupled with the resistors and disposed inside the external shield. A first internal resistor is disposed inside the external shield and outside of the internal shield(s). One or more remaining resistors are inside the internal shield(s). The shields divide parasitic capacitances to enable the measurement of dynamically changing high voltage input signals.Type: GrantFiled: June 17, 2016Date of Patent: November 13, 2018Assignee: General Electric CompanyInventor: Antonio Caiafa
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Patent number: 10110013Abstract: A switch assembly includes one or more solid state semiconductor switches configured to be disposed within a downhole pipe assembly. The one or more switches are configured to operate in a closed state to conduct electric current supplied by a power source disposed above a surface to pumps disposed beneath the surface to cause the pumps to extract a resource from beneath the surface via the pipe assembly. The one or more switches also are configured to operate in an open state to stop conducting the electric current from the power source to the pumps.Type: GrantFiled: July 24, 2015Date of Patent: October 23, 2018Assignee: General Electric CompanyInventors: Dong Dong, Antonio Caiafa, Mohammed Agamy, Ahmed Elasser, Philip Michael Cioffi
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Publication number: 20180237764Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.Type: ApplicationFiled: April 17, 2018Publication date: August 23, 2018Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
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Publication number: 20180191268Abstract: A power system includes a first unit block having first resonant circuitry that receives power from a DC bus, a first controlled rectifier that provides a first portion of power to one or more loads at a first voltage level, and a first transformer coupled between the first resonant circuitry and the first controlled rectifier. A second unit block includes second resonant circuitry that receives power from the DC bus, a second controlled rectifier configured to provide a second portion of power to the one or more loads at a second voltage level, and a second transformer coupled between the resonant circuitry and the controlled rectifier. The first and second unit blocks are coupled in series to output a summation waveform.Type: ApplicationFiled: January 5, 2017Publication date: July 5, 2018Inventor: Antonio Caiafa
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Publication number: 20180191262Abstract: A cryogenic fuel power system includes an engine. The cryogenic fuel power system includes a cryogenic fuel supply that supplies cryogenic fuel to be used as fuel by the engine. The cryogenic fuel power system includes a cryogenic bus configured to provide the cryogenic fuel from the cryogenic fuel supply to the engine. The cryogenic fuel power system includes power electronics circuitry that converts power from the engine into a form to be applied to one or more loads. The power electronics circuitry is positioned in thermal communication with the cryogenic bus to transfer heat from the power electronics circuitry to the cryogenic fuel.Type: ApplicationFiled: January 5, 2017Publication date: July 5, 2018Inventor: Antonio Caiafa
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Publication number: 20180123350Abstract: A switching system includes a transformer and a switching assembly for controlling conduction of current from a power source to a first load along a power cable. The switching assembly includes a switch cell conductively coupled to the power cable. The transformer has a primary winding and a secondary winding. The secondary winding is conductively coupled to the switch cell. The primary winding is conductively coupled to a switch controller via the power cable. The transformer is configured to receive an activation control signal from the switch controller at the primary winding via the power cable and convey the activation control signal to the switch cell via the secondary winding. The switch cell is configured to activate and conduct the current from the power source to the first load along the power cable responsive to receiving the activation control signal from the switch controller.Type: ApplicationFiled: October 31, 2016Publication date: May 3, 2018Inventors: Antonio Caiafa, Ahmed Elasser, Dong Dong
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Publication number: 20180123468Abstract: A switching system includes a switching assembly and a transformer. The switching assembly includes multiple sets of switch cells conductively coupled to different power conductors that extend between a power source and a load and conduct different phases of current. Each set of switch cells controls conduction of a different phase of current to the load. The transformer has a primary winding and multiple secondary windings that are conductively coupled to the sets of switch cells. Responsive to receiving an activation control signal from the transformer via the secondary windings, the sets of switch cells are configured to activate to conduct the multiple phases of current from the power source to the load along the power conductors.Type: ApplicationFiled: October 31, 2016Publication date: May 3, 2018Inventors: Antonio Caiafa, Ahmed Elasser, Dong Dong
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Publication number: 20180068823Abstract: An X-ray tube is provided. The X-ray tube includes an electron beam source including a cathode configured to emit an electron beam. The X-ray tube also includes an anode assembly including an anode configured to receive the electron beam and to emit X-rays when impacted by the electron beam. The X-ray tube further includes a gridding electrode disposed about a path of the electron beam between the electron beam source and the anode assembly. The gridding electrode, when powered at a specific level, is configured to grid the electron beam in synchronization with planned transitions during a dynamic focal spot mode.Type: ApplicationFiled: September 7, 2016Publication date: March 8, 2018Inventors: Michael John Utschig, Uwe Wiedmann, Bruno Kristiaan Bernard De Man, Sergio Lemaitre, Mark Alan Frontera, Antonio Caiafa, Jiahua Fan, Adam Budde
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Patent number: 9856722Abstract: Power systems and methods are disclosed herein. The systems and methods use a switching system coupled with a power source and subterranean pumps for pumping a resource from beneath a surface of earth. A first capacitor is between a first switching device and a first transformer, and stores electric energy received from the first transformer to activate the first switching device. A bias capacitor is between the first capacitor and the first switching device, and receives a bias voltage via a second transformer. The bias capacitor applies the bias voltage to the first switching device to prevent the first switching device from activating unless a combination of the voltage received by the first switching device via the first transformer and the bias voltage is at least as large as the activation voltage of the first switching device.Type: GrantFiled: July 24, 2015Date of Patent: January 2, 2018Assignee: General Electric CompanyInventors: Dong Dong, Antonio Caiafa, Mohammed Agamy, Ahmed Elasser
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Publication number: 20170367174Abstract: A voltage divider circuit assembly includes resistors, an external electrostatic shield, and internal electrostatic shield(s). The resistors are in series with each other between input terminals that receive an input voltage. An external resistor is disposed between sensing terminals that conduct an output voltage that is the input voltage divided by the resistors in the series. The external shield is conductively coupled with the series of the resistors with the external resistor disposed outside of the external shield and the other resistor(s) inside the external shield. The internal shield(s) are conductively coupled with the resistors and disposed inside the external shield. A first internal resistor is disposed inside the external shield and outside of the internal shield(s). One or more remaining resistors are inside the internal shield(s). The shields divide parasitic capacitances to enable the measurement of dynamically changing high voltage input signals.Type: ApplicationFiled: June 17, 2016Publication date: December 21, 2017Inventor: ANTONIO CAIAFA