Patents by Inventor Anuj Chauhan

Anuj Chauhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210169796
    Abstract: In one aspect, the disclosure relates to compositions for the extended release of drugs in the retina. In a further aspect, the present disclosure provides methods of preparing extended release compositions comprising a therapeutic agent for use in retinal drug delivery. In various other aspects, the present disclosure provides methods for delivery of the disclosed compositions comprising a therapeutic agent to the retina via intravitreal injection. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Application
    Filed: November 28, 2018
    Publication date: June 10, 2021
    Inventors: Anuj Chauhan, Russell Macoon
  • Publication number: 20210121325
    Abstract: In one aspect, the disclosure relates to drug delivery devices for the ionophoretic delivery of a therapeutic agent(s) to the eye. In some aspects, the disclosed ionophoretic ocular delivery device is configured for delivery of a therapeutic agent to the anterior portion of the eye. In various aspects, the present disclosure provides methods for treatment of an ophthalmological disorder, disease, or clinical condition by delivering a therapeutic agent(s) to the eye using a disclosed ionophoretic ocular delivery device. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Application
    Filed: August 2, 2019
    Publication date: April 29, 2021
    Inventors: Anuj Chauhan, Keith G. Christopher
  • Publication number: 20200368107
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Application
    Filed: August 6, 2020
    Publication date: November 26, 2020
    Inventors: Anuj Chauhan, Phillip J. Dixon, Poorvajan Sekar
  • Patent number: 10786429
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: September 29, 2020
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Phillip J. Dixon, Poorvajan Sekar
  • Publication number: 20200284951
    Abstract: In one aspect, the present disclosure relates to a contact lens comprising a disclosed lubricious surface layer. In a further aspect, the lubricious surface layer comprises a polyacrylamide, e.g., a poly(N,N-dimethylacrylamide. In various aspects, the lubricious surface layer is formed at the surface of a contact lens. In a further aspect, the lens can be a hydrogel lens. In a further aspect, the lens can be a silicone hydrogel lens. The present disclosure also pertains to methods of forming the disclosed lubricious surface layers on a surface of a contact lens. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Application
    Filed: October 4, 2018
    Publication date: September 10, 2020
    Inventors: Anuj Chauhan, Kuan-Hui Hsu, Yifan Yu
  • Publication number: 20200253867
    Abstract: According to some aspects, this application provides devices and methods for treating cystinosis in a patient. Removable intra-ocular devices and contact lenses containing cystine-sequestering materials effective for uptake of cystine from the eyes of a patient having cystinosis are provided. Methods of making the cystine-sequestering contact lenses are also provided.
    Type: Application
    Filed: September 21, 2018
    Publication date: August 13, 2020
    Inventors: Anuj CHAUHAN, Phillip J. DIXON
  • Publication number: 20200156336
    Abstract: In general, the disclosure relates to methods and compositions for preparing colorants useful for preparing pigmented hydrogels. The disclosure further relates to pigmented hydrogels comprising the disclosed colorants. In some instances, the colorant is an alcohol extract of an agro-material, such as turmeric, paprika, spinach, and/or woad or the colorants comprise one or more of: a carotenoid, chlorophyll-a, chlorophyll-b, a curcumoid, or indigorubin. Alternatively, the colorant can be carbon black. The disclosure further relates to contact lenses comprising the disclosed pigmented hydrogels.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Inventors: Anuj Chauhan, Phillip J. Dixon, Poorvajan Sekar
  • Publication number: 20190358180
    Abstract: Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O2. Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O2 entering the contact lens holder.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 28, 2019
    Inventors: Anuj Chauhan, Phillip J. Dixon
  • Publication number: 20190307641
    Abstract: The present disclosure relates to nozzles for removing a preservative from a fluid comprising a therapeutic agent to an eye. More particularly, the nozzles disclosed herein may minimize patient exposure to preservative by rapidly and selectively removing a preservative from a solution comprising a therapeutic agent. An example nozzle may comprise a flow diverter which directs a flow path from a fluid inlet to a fluid outlet over a length longer than the distance from the inlet to the outlet. In some cases, the nozzle may comprise a preservative removing agent.
    Type: Application
    Filed: April 5, 2019
    Publication date: October 10, 2019
    Inventors: Howard L. GOLUB, Anuj CHAUHAN, Michael WILLIAMS
  • Publication number: 20190269575
    Abstract: A particulate plug for removing a preservative from a solution, suspension, or emulsion comprising a drug is presented. The plug comprises microparticles of a homopolymer comprising a hydrophilic repeating unit or of a copolymer comprising at least one hydrophilic repeating unit and at least one hydrophobic repeating unit. The microparticles are irregular-shaped rigid aggregates and are sized and packed to yield a hydraulic permeability greater than 0.01 Da. The homopolymers have absorbed portions of a preservative to be removed and/or a drug for delivery in solution, as can the copolymer.
    Type: Application
    Filed: April 18, 2019
    Publication date: September 5, 2019
    Inventors: Anuj Chauhan, Phillip J. Dixon, Poorvajan Sekar
  • Publication number: 20190247277
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Application
    Filed: April 23, 2019
    Publication date: August 15, 2019
    Inventors: Anuj Chauhan, Phillip J. Dixon, Poorvajan Sekar
  • Publication number: 20190117450
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Application
    Filed: October 22, 2018
    Publication date: April 25, 2019
    Inventors: Anuj Chauhan, Kuan-Hui Hsu
  • Patent number: 10123904
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: November 13, 2018
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Kuan-Hui Hsu
  • Patent number: 9885886
    Abstract: UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: February 6, 2018
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Anuj Chauhan, Hyun-Jung Jung, Samuel B. Gause
  • Publication number: 20170224531
    Abstract: A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 ?m and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 ?m.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 10, 2017
    Inventors: Anuj CHAUHAN, Kuan-Hui HSU
  • Publication number: 20170212365
    Abstract: UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent.
    Type: Application
    Filed: March 2, 2017
    Publication date: July 27, 2017
    Inventors: Anuj Chauhan, Hyun-Jung Jung, Samuel B. Gause
  • Patent number: 9594188
    Abstract: UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: March 14, 2017
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Anuj Chauhan, Hyun-Jung Jung, Samuel B. Gause
  • Publication number: 20160354240
    Abstract: A device for the delivery of eye drops to one or both eyes of a patient includes a frame for placement over the patient's eyes, a holder for a commercially available eye drop bottle and a fluid delivery means. The eye drop delivery device can include a video camera to monitor the opening and closing of the eyes and a processor or a connector to a remote processor with software to receive input from the camera and deliver output to the delivery means to start and stop delivery of eye drops to the patient's eye.
    Type: Application
    Filed: August 16, 2016
    Publication date: December 8, 2016
    Inventors: Anuj Chauhan, Carrie Chauhan
  • Publication number: 20160296476
    Abstract: Disclosed herein is a composition comprising a biologically active agent; a base oil; an additional oil that is soluble in the base oil with a partition coefficient for the biologically active molecule that is at least twice that of the base oil; where the base oil and the additional oil are present in the composition in an amount effective to reduce the amount of the biologically active agent in an aqueous phase to less than 80 wt % of the amount with just the base oil present in an otherwise identical composition at the same total oil loading; a non-ionic surfactant; and water.
    Type: Application
    Filed: October 9, 2014
    Publication date: October 13, 2016
    Inventor: Anuj Chauhan
  • Publication number: 20150057389
    Abstract: A wettable hydrogel or a silicone hydrogel device includes a polymerized surfactant incorporated into the gel by addition to a gel, on average, of a single ethylenic functionality of the precursor polymerizable surfactant in the polymerization mixture. The attached polymerized surfactant provides improved lubricity to the hydrogel or silicone hydrogel device. Alternately, a wettable hydrogel or a silicone hydrogel device can be formed by soaking a preformed hydrogel or a silicone hydrogel device in a solution of the polymerizable surfactant and a radical initiator and promoting the polymerization of the polymerizable surfactant and available polymerizable groups on or in the device. The wettable hydrogel or a silicone hydrogel device can be a contact lens.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Inventors: ANUJ CHAUHAN, LOKENDRAKUMAR CHAINROOM KUMAR BENGANI