Patents by Inventor Anuj Chauhan

Anuj Chauhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140288206
    Abstract: UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventors: Anuj Chauhan, Hyun-Jung Jung, Samuel B. Gause
  • Patent number: 8404265
    Abstract: An appliance for the delivery of at least one bioactive agent to the eye has at least one diffusion attenuator within a hydrophilic or silicone-hydrogel contact lens. The bioactive agent can be a drug or a nutraceutical. The diffusion attenuator can be a plurality of solid particles or phase separated liquid aggregates within at least one continuous phase of the lens where the diffusion attenuators promote a tortuous path for the diffusion of the bioactive agent to mediate the rate by which the bioactive agent diffuses from the contact lens. The diffusion attenuator can be homogeneously dispersed throughout at least one continuous phase of the lens to modify the diffusivity of the bioactive agent through that phase. The diffusion attenuator can have little or no affinity for the bioactive agent or can be miscible with the bioactive agent. The diffusion attenuator can be incorporated while forming the contact lens by polymerization of a monomer mixture containing the diffusion attenuator.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: March 26, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Jinah Kim
  • Patent number: 8273366
    Abstract: A drug delivery system comprising a contact lens having dispersed therein as nanoparticles having a particle size less than about 200 nm, an ophthalmic drug nanoencapsulated in a material from which said ophthalmic drug is capable of diffusion into and migration through said contact lens and into the post-lens tear film when said contact lens is placed on the eye.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: September 25, 2012
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Derya Gulsen
  • Patent number: 8075909
    Abstract: A bioactive agent delivery system comprising an optically transparent contact lens having dispersed therein (1) an ophthalmically bioactive agent capable of diffusion through the contact lens and into the post-lens tear film when placed on the eye and (2) associated with the bioactive agent, an ophthalmically compatible polymeric surfactant in an amount sufficient to slow the rate of migration of the bioactive agent through the contact lens.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: December 13, 2011
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Yash Kapoor
  • Patent number: 8071121
    Abstract: An ophthalmically bioactive agent delivery system comprising a contact lens having dispersed therein as an oil-in-water microemulsion, an ophthalmically bioactive agent encapsulated in the oil phase, the oil phase comprising a material from which the agent VAN diffuse into and migrate through the contact lens into the post-lens tear film when the contact lens is placed on the eye and wherein the microemulsion is stabilized by the presence of a surfactant with sufficient packing at the oil-water interface to attenuate the rate of diffusion into and migration of agent through the contact lens.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: December 6, 2011
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Derya Gulsen Onbilger, Yash Kapoor, Chi-Chung Li
  • Publication number: 20110217355
    Abstract: A bioactive agent delivery system comprising an optically transparent contact lens having dispersed therein (1) an ophthalmically bioactive agent capable of diffusion through the contact lens and into the post-lens tear film when placed on the eye and (2) associated with the bioactive agent, an ophthalmically compatible polymeric surfactant in an amount sufficient to slow the rate of migration of the bioactive agent through the contact lens.
    Type: Application
    Filed: September 4, 2008
    Publication date: September 8, 2011
    Inventor: Anuj Chauhan
  • Publication number: 20100330146
    Abstract: An appliance for the delivery of at least one bioactive agent to the eye has at least one diffusion attenuator within a hydrophilic or silicone-hydrogel contact lens. The bioactive agent can be a drug or a nutraceutical. The diffusion attenuator can be a plurality of solid particles or phase separated liquid aggregates within at least one continuous phase of the lens where the diffusion attenuators promote a tortuous path for the diffusion of the bioactive agent to mediate the rate by which the bioactive agent diffuses from the contact lens. The diffusion attenuator can be homogeneously dispersed throughout at least one continuous phase of the lens to modify the diffusivity of the bioactive agent through that phase. The diffusion attenuator can have little or no affinity for the bioactive agent or can be miscible with the bioactive agent. The diffusion attenuator can be incorporated while forming the contact lens by polymerization of a monomer mixture containing the diffusion attenuator.
    Type: Application
    Filed: July 22, 2010
    Publication date: December 30, 2010
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC.
    Inventors: ANUJ CHAUHAN, JINAH KIM
  • Publication number: 20100310622
    Abstract: A punctal plug and method of treating dry eyes are provided. The punctal plug has two or three layer structure and contains at least one drug, for treating conditions such as dry eyes contained in a core, a potion of which is covered by a drug impermeable shell such that drug can radially diffuse from the core. The punctal plug can be inserted into a patient's upper punctum, lower punctum, or both to deliver the drug for an extended period of time. The drug for treating dry eyes can be, for example, cyclosporine A. The plug can also be used for extended delivery of ophthalmic drugs.
    Type: Application
    Filed: December 17, 2008
    Publication date: December 9, 2010
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Anuj Chauhan, Heng Zhu
  • Publication number: 20100178316
    Abstract: A dosage form for the administration of a biologically active agent is a silicone hydrogel appliance where the agent is absorbed in a copolymer of at least one siloxane containing monomer and at least one hydrophilic monomer where the appliance is placed in contact with a tissue surface of the patient, such as a contact lens placed in the eye. The appliance can be formed where a copolymer of the siloxane containing and hydrophobic monomers is soaked in a solution of the biologically active agent. The agent can be a non-ionic drug which is absorbed into the appliance from a non-aqueous solution, such as an ethanol solution.
    Type: Application
    Filed: May 30, 2008
    Publication date: July 15, 2010
    Inventors: Anuj Chauhan, Jinah Kim
  • Patent number: 7638137
    Abstract: A drug delivery system comprising a contact lens having dispersed therein as nanoparticles having a particle size less than about 50 nm, an ophthalmic drug nanoencapsulated in a material from which said ophthalmic drug is capable of diffusion into and migration through said contact lens and into the post-lens tear film when said contact lens is placed on the eye.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: December 29, 2009
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Anuj Chauhan, Derya Gulsen
  • Publication number: 20090060981
    Abstract: A bioactive agent delivery system comprising an optically transparent contact lens having dispersed therein (1) an ophthalmically bioactive agent capable of diffusion through the contact lens and into the post-lens tear film when placed on the eye and (2) associated with the bioactive agent, an ophthalmically compatible polymeric surfactant in an amount sufficient to slow the rate of migration of the bioactive agent through the contact lens.
    Type: Application
    Filed: September 4, 2007
    Publication date: March 5, 2009
    Inventor: Anuj Chauhan
  • Publication number: 20080075757
    Abstract: An ophthalmically bioactive agent delivery system comprising a contact lens having dispersed therein as an oil-in-water microemulsion, an ophthalmically bioactive agent encapsulated in the oil phase, the oil phase comprising a material from which the agent VAN diffuse into and migrate through the contact lens into the post-lens tear film when the contact lens is placed on the eye and wherein the microemulsion is stabilized by the presence of a surfactant with sufficient packing at the oil-water interface to attenuate the rate of diffusion into and migration of agent through the contact lens.
    Type: Application
    Filed: September 4, 2007
    Publication date: March 27, 2008
    Inventors: Anuj Chauhan, Derya Gulsen
  • Publication number: 20040241207
    Abstract: A drug delivery system comprising a contact lens having dispersed therein as nanoparticles having a particle size less than about 200 nm, an ophthalmic drug nanoencapsulated in a material from which said ophthalmic drug is capable of diffusion into and migration through said contact lens and into the post-lens tear film when said contact lens is placed on the eye.
    Type: Application
    Filed: March 17, 2004
    Publication date: December 2, 2004
    Inventors: Anuj Chauhan, Derya Gulsen
  • Publication number: 20040096477
    Abstract: A drug delivery system comprising a contact lens having dispersed therein as nanoparticles having a particle size less than about 50 nm, an ophthalmic drug nanoencapsulated in a material from which said ophthalmic drug is capable of diffusion into and migration through said contact lens and into the post-lens tear film when said contact lens is placed on the eye.
    Type: Application
    Filed: June 5, 2003
    Publication date: May 20, 2004
    Inventors: Anuj Chauhan, Derya Gulsen