Abstract: Disclosed are compounds for use in raising an immune response to an antigen and/or enhancing, modulating or augmenting an immune response to an antigen. Particularly the use of urolithins. The invention also relates to immune enhancers comprising urolithins, methods of using such immune enhancers and processes for the preparation of such immune enhancers. The invention also relates to the use of urolithins in methods for modulating stem cell function, for example, enhancing stem cell numbers, promoting stem cell regeneration and promoting stem cell differentiation.

Abstract: Digital content design system techniques are described using baseline units to control arrangement and sizing of digital content. In one example, a digital content design system receives a user input specifying a number of baselines to be included within an available display area of a page. Baselines are used to align digital content to control arrangement of the digital content within the page, e.g., text. From this, the digital content design system then calculates a baseline unit from a distance used to space adjacent baselines of the number of baselines from each other. This baseline unit is then leveraged by the system as a fundamental unit of measure to control arrangement and/or sizing of digital content in relation to each other.

Abstract: Techniques for transforming digital text content using expressions are described. According to various implementations, a text editor system determines that digital text content of a digital document is modified via application of a particular style that differs from other digital text content of the digital document. The text editor system identifies a pattern characteristic to the modified digital text content, and generates a digital expression that identifies the pattern, and generates a style expression that combines the digital expression with a digital style that represents style attributes descriptive of the style modification applied to the modified text content. The text editor system applies the style expression to search digital text content, identify matching digital text content that matches the digital expression, and transform the matching digital text content by applying the digital style to modify the matching digital text content.

Abstract: Digital content design system techniques are described using baseline units to control arrangement and sizing of digital content. In one example, a digital content design system receives a user input specifying a number of baselines to be included within an available display area of a page. Baselines are used to align digital content to control arrangement of the digital content within the page, e.g., text. From this, the digital content design system then calculates a baseline unit from a distance used to space adjacent baselines of the number of baselines from each other. This baseline unit is then leveraged by the system as a fundamental unit of measure to control arrangement and/or sizing of digital content in relation to each other.

Abstract: The present disclosure relates to a formulation including: a) a dendron of Formula I; b) at least one bio-therapeutic; c) at least one buffer; and d) at least one salt, wherein the bio-therapeutic to dendron molar ratio is in the range of 1:0.5-1:3. The dendron stabilizes the bio-therapeutic in the formulation at a temperature of up to 55° C.

Abstract: Digital content design system techniques are described using baseline units to control arrangement and sizing of digital content. In one example, a digital content design system receives a user input specifying a number of baselines to be included within an available display area of a page. Baselines are used to align digital content to control arrangement of the digital content within the page, e.g., text. From this, the digital content design system then calculates a baseline unit from a distance used to space adjacent baselines of the number of baselines from each other. This baseline unit is then leveraged by the system as a fundamental unit of measure to control arrangement and/or sizing of digital content in relation to each other.

Abstract: The present disclosure provides a method and system to detect advertisement fraud. The fraud detection platform receives device data and application data associated with one or more advertisements published on at least one publisher on one or more media devices. In addition, the fraud detection platform identifies a plurality of parameters based on the device data and the application data. Further, the fraud detection platform generates a plurality of graphs based on the device data, the application data, user behavior and the plurality of parameters. Furthermore, the fraud detection platform analyzes the plurality of graphs with trained data to identify fraud based on the deviation.

Abstract: The present disclosure provides a method and system to detect advertisement fraud. The fraud identification system receives a traffic data initiated through a plurality of users. In addition, the fraud identification system clusters the traffic data into slots of install based on one of a plurality of criteria and determine high conversion rate and low conversion rate. Further, the fraud identification system analyzes deviation of the high conversion rate and the low conversion rate with a pre-defined threshold. Furthermore, the fraud identification system analyzes the slots of install for which difference between the average of the high conversion rate and the low conversion rate is above the pre-defined threshold. Also, the fraud identification system segregates incentive traffic and non-incentive traffic based on the analysis. The segregation is done to generate report of the traffic data and determine incentive time.

Abstract: Disclosed are compounds for use in raising an immune response to an antigen and/or enhancing, modulating or augmenting an immune response to an antigen. Particularly the use of urolithins. The invention also relates to immune enhancers comprising urolithins, methods of using such immune enhancers and processes for the preparation of such immune enhancers. The invention also relates to the use of urolithins in methods for modulating stem cell function, for example, enhancing stem cell numbers, promoting stem cell regeneration and promoting stem cell differentiation.

Abstract: The present disclosure provides a method and system for distribution of mobile advertisement fraud data to one or more third parties. The data sharing platform receives a connection request from one or more third parties to access fraud data. In addition, the data sharing platform correlate the third party data from the one or more third parties and the fraud data. Further, the data sharing platform optimize selected rules for the identification of fraud done by the publisher. Furthermore, the data sharing platform analyze publisher data, application data and the fraud data collected after correlation. Moreover, the data sharing platform generates report in a pre-defined interval of time. Also, the data sharing platform shares the report with the one or more third parties based on a pre-defined criteria.

Abstract: The present disclosure provides a system for detection of online advertisement fraud and commerce fraud. The system includes a first step of collecting a first set of data from a plurality of components associated with each device of a plurality of devices and receiving a second set of data associated with each device of a plurality of third party devices. The system includes yet another step of calculating a probabilistic score for detection of the online advertisement and the commerce fraud in real-time. The system includes yet another step of analyzing the first set of data and the second set of data after a periodic interval of time. The system includes another step of detecting the online advertisement fraud and commerce fraud based on the analysis of the first set of data and the second set of data.

Abstract: The present disclosure provides a method and system to detect advertisement fraud. The system receives the IP address data which is being used for viewing one or more advertisements published on at least one publisher on one or more media devices. In addition, the system classifies the IP address data into a plurality of classes. Further, the system analyzes abnormal traffic based on a plurality of parameters and the IP address data. Moreover, the system allocates the IP address into a blacklist when score exceeds threshold limit.

Abstract: The present disclosure provides a method and system for creating decentralized repository of fraud IP and publishers using block chain. The block chain network creates a central repository for decentralized shared ledger. The block chain network adds a ledger in decentralized shared ledger for each interaction on an application. In addition, the block chain network authorizes at least one of a plurality of stakeholders to access the decentralized shared ledger after receiving a request from at least one of the plurality of stakeholders. Further, the block chain network analyzes the interaction and past data received from a plurality of stake holders. Furthermore, the block chain network blocks device IPs, device Id's, device type and the publishers mentioned in blacklist of the decentralized shared ledger.

Abstract: The present disclosure provides a system for utilization of an advertisement fraud data to blacklist or whitelist one or more entities. The system includes a first step of collecting the advertisement fraud data associated with online advertisement and commerce fraud. The system includes another step of creating a blacklist of one or more entities from the collected advertisement fraud data. The system includes another step of blocking the one or more entities present in the created blacklist in real-time. The system includes another step of generating a whitelist of one or more entities from the created blacklist of the one or more entities. The system includes yet another step of optimizing the blacklist of the one or more entities in real-time.

Abstract: The present invention describes a method of dynamic gamification over a network and comprises of the steps of creating a network of statistical models associated with a real life situation by using a processor, modifying a predefined parameter of a first statistical model by either a player or a moderator which triggers a modification subsequently in the other statistical models related to the first statistical model and deciding an outcome of the gamification in response to the modification of the first and the other statistical models.

Abstract: The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prophylaxis of a condition, disease or disorder in a subject, wherein the compound or salt is orally administered to a subject in a daily amount of from 1.7 to 2.7 mmol per day, over a period of at least 21 days. Also are provided are the compound of formula (I) for use in increasing mitophagy and/or autophagy, maintaining and/or improving muscle function and administration as a dietary, nutritional and/or health supplement.

Abstract: The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prophylaxis of a condition, disease or disorder in a subject, wherein the compound or salt is orally administered to a subject in a daily amount of from 2.8 to 6.6 mmol per day, over a period of at least 21 days. Also are provided are the compound of formula (I) for use in increasing mitophagy and/or autophagy, maintaining and/or improving muscle function and administration as a dietary, nutritional and/or health supplement.

Abstract: The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prevention of a skin condition in a subject, wherein the compound of formula (I) or salt thereof is administered topically. The invention further provides topical compositions of a compound of formula (i) and processes for the preparation of said compositions.