Patents by Inventor Armin Kuebelbeck

Armin Kuebelbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230272014
    Abstract: The disclosure relates to a composition of nanoparticles as carrier for HPV-derived immunogenic fragments and the use of the composition for medical purposes, in particular for immunoprophylaxis or immunotherapy. The invention also relates to a vaccine containing the composition and/or nanoparticles.
    Type: Application
    Filed: May 12, 2021
    Publication date: August 31, 2023
    Applicants: Life Science Inkubator Betriebs GmbH & Co. KG, Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts
    Inventors: Armin KÜBELBECK, Angelika RIEMER, Sebastian KRUSE, Eva FEIDT, Agnieszka GRABOWSKA, Ellen JUNGLAS
  • Publication number: 20230181727
    Abstract: The disclosure relates to a composition of nanoparticles as carrier for pharmaceutically acceptable compounds, a method for the preparation of the composition and the use of the composition for medical purposes, in particular for immunoprophylaxis or immunotherapy. The invention also relates to a vaccine containing the composition.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 15, 2023
    Applicant: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventor: Armin KÜBELBECK
  • Patent number: 10413614
    Abstract: The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: September 17, 2019
    Assignee: Merck Patent GmbH
    Inventors: Armin Kuebelbeck, Gregor Larbig, Stefan Arnold, Walter Mier, Uwe Haberkorn
  • Patent number: 10111952
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: October 30, 2018
    Assignee: MERCK PATENT GmbH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Patent number: 10065993
    Abstract: The present invention relates to a peptide which consists of more than 50% of sequence sections of the formula -(An-Bm-Co)-, and to a conjugate containing the peptide and at least one covalently bonded active compound, and to a process for the preparation of the conjugate. The present invention furthermore relates to the use of the peptide and the conjugate for targeting of the kidney, and to a medicament comprising the peptide or conjugate.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 4, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Armin Kuebelbeck, Gregor Larbig, Stefan Arnold, Walter Mier
  • Publication number: 20180071386
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.
    Type: Application
    Filed: October 6, 2017
    Publication date: March 15, 2018
    Applicant: Merck Patent GmbH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Publication number: 20180015173
    Abstract: The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.
    Type: Application
    Filed: October 3, 2017
    Publication date: January 18, 2018
    Applicant: Merck Patent GmbH
    Inventors: Armin KUEBELBECK, Gregor LARBIG, Stefan ARNOLD, Walter MIER, Uwe HABERKORN
  • Patent number: 9808535
    Abstract: The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: November 7, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Armin Kuebelbeck, Gregor Larbig, Stefan Arnold, Walter Mier, Uwe Haberkorn
  • Patent number: 9808521
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunization of a mammal.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: November 7, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Publication number: 20160303228
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.
    Type: Application
    Filed: June 30, 2016
    Publication date: October 20, 2016
    Applicant: Merck Patent GmbH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Patent number: 9433673
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunization of a mammal.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: September 6, 2016
    Assignee: MERCK PATENT GMBH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Publication number: 20160199505
    Abstract: The present invention relates to a peptide which consists of more than 50% of sequence sections of the formula -(An-Bm-Co)-, and to a conjugate containing the peptide and at least one covalently bonded active compound, and to a process for the preparation of the conjugate. The present invention furthermore relates to the use of the peptide and the conjugate for targeting of the kidney, and to a medicament comprising the peptide or conjugate.
    Type: Application
    Filed: April 16, 2014
    Publication date: July 14, 2016
    Applicant: MERCK PATENT GMBH
    Inventors: Armin KUEBELBECK, Gregor LARBIG, Stefan ARNOLD, Walter MIER
  • Publication number: 20160114054
    Abstract: The present invention relates to a conjugate containing at least one kidney-selective carrier molecule and at least one active compound which has a protective action for the kidney against nephrotoxic active compounds, to a process for the preparation of the conjugate, to the use thereof for the protection of the kidney against nephrotoxic active compounds, and to a medicament comprising the conjugate.
    Type: Application
    Filed: April 16, 2014
    Publication date: April 28, 2016
    Applicant: Merck Patent GmbH
    Inventors: Armin KUEBELBECK, Gregor LARBIG, Stefan ARNOLD, Walter MIER, Uwe HABERKORN
  • Publication number: 20150224189
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.
    Type: Application
    Filed: February 2, 2015
    Publication date: August 13, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Patent number: 9078929
    Abstract: The present invention relates to ?-polylysine conjugates, in particular conjugates of ?-polylysine with compounds carrying carboxyl groups, and to the preparation and use thereof for targeting of the kidney.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: July 14, 2015
    Assignee: Merck Patent GmbH
    Inventors: Armin Kuebelbeck, Gregor Larbig, Walter Mier, Barbro Beijer, Uwe Haberkorn
  • Patent number: 8980324
    Abstract: The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunization of a mammal.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: March 17, 2015
    Assignee: Merck Patent GmbH
    Inventors: Markus Weigandt, Andrea Hanefeld, Armin Kuebelbeck, Gregor Larbig
  • Patent number: 8795549
    Abstract: The present invention relates to novel printable etching media having improved properties for use in the process for the production of solar cells. These are corresponding particle-containing compositions by means of which extremely fine lines and structures can be etched very selectively without damaging or attacking adjacent areas.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: August 5, 2014
    Assignee: Merck Patent GmbH
    Inventors: Werner Stockum, Armin Kuebelbeck
  • Patent number: 8540891
    Abstract: The invention relates to novel etching media in the form of etching pastes for etching selected areas or the entire area of silicon surfaces and layers, in addition to the use of said media.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: September 24, 2013
    Assignee: Merck Patent GmbH
    Inventors: Armin Kübelbeck, Sylke Klein, Werner Stockum
  • Patent number: 8257617
    Abstract: To provide functional paste with etching activity and good electrical properties. Functional paste comprising a metal powder, an etching agent, a binder and an organic solvent.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: September 4, 2012
    Assignee: Merck Patent GmbH
    Inventors: Sylke Klein, Armin Kuebelbeck, Werner Stockum, Jun Nakanowatari, Kiyohiko Kawamoto, Katsumi Tanino
  • Publication number: 20120122788
    Abstract: The present invention relates to ?-polylysine conjugates, in particular conjugates of ?-polylysine with compounds carrying carboxyl groups, and to the preparation and use thereof for targeting of the kidney.
    Type: Application
    Filed: July 9, 2010
    Publication date: May 17, 2012
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Armin Kuebelbeck, Gregor Larbig, Walter Mier, Barbro Beijer, Uwe Haberkorn