Patents by Inventor Arndt Rolfs

Arndt Rolfs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE DIAGNOSIS OF METACHROMATIC LEUKODYSTROPHY
    Publication number: 20150316563
    Abstract: The present invention is related to a method for diagnosing metachromatic leukodystrophy in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject, wherein the sample is selected from the group consisting of blood, dried blood, serum and plasma and wherein the biomarker is different from an enzyme.
    Type: Application
    Filed: December 11, 2013
    Publication date: November 5, 2015
    Applicants: PHARM-ANALYT LABOR GMBH, CENTOGENE AG
    Inventors: ARNDT ROLFS, HERMANN MASCHER
  • USE OF MALEIMIDE DERIVATIVES FOR PREVENTING AND TREATING LEUKEMIA
    Publication number: 20150306070
    Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.
    Type: Application
    Filed: December 10, 2013
    Publication date: October 29, 2015
    Applicant: CENTOGENE AG
    Inventors: MATTHIAS BELLER, JAN LUKAS, MORITZ FRECH, CHRISTIAN JUNGHANSS, ARNDT ROLFS, ANAHIT PEWS-DAVTYAN, CHRISTIAN EISENLOEFFEL
  • COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL
    Publication number: 20150258081
    Abstract: It is herewith declared that the information stored on the carrier which is submitted together with the international patent application is identical to the written sequence listing of the international patent application.
    Type: Application
    Filed: December 21, 2012
    Publication date: September 17, 2015
    Applicant: Centogene IP GmbH
    Inventors: Jan Lukas, Anahit Pews-Davtyan, Mathias Beller, Arndt Rolfs
  • METHOD FOR THE DIAGNOSIS OF NIEMANN-PICK DISEASE
    Publication number: 20140309140
    Abstract: The present invention is related to a method for diagnosing Niemann-Pick disease in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject.
    Type: Application
    Filed: November 15, 2012
    Publication date: October 16, 2014
    Inventors: Arndt Rolfs, Hermann Mascher
  • METHOD FOR THE DIAGNOSIS OF GAUCHER'S DISEASE
    Publication number: 20140187439
    Abstract: The present invention is related to an in vitro method for diagnosing Gaucher's disease in a subject comprising a step of a) detecting a biomarker in a sample from the subject, wherein the biomarker is free lyso-Gb1.
    Type: Application
    Filed: June 6, 2012
    Publication date: July 3, 2014
    Inventors: Arndt Rolfs, Hermann Mascher
  • Analytical detection of
    Patent number: 7002005
    Abstract: A kit and a nucleic acid molecule primer and/or probe for the analytical detection of Staphylococcus aureus are disclosed. The detection employs nucleic acid amplification and/or nucleic acid hybridization.
    Type: Grant
    Filed: July 21, 1998
    Date of Patent: February 21, 2006
    Assignee: Biotecon Diagnostics GmbH
    Inventors: Kornelia Berghof, Alexander Gasch, Charles Mason-Brown, Freimut Wilborn, Arndt Rolfs
  • Amino acid sequences and method for isolating bacteries from the type genus pseudomonas
    Patent number: 6893817
    Abstract: The present invention relates to a nucleic acid molecule or molecules and to a process for the detection of bacteria of the Pseudomonas genus, especially Pseudomonas aeruginosa. The invention relates also to a test kit or kits for carrying out the said detection processes.
    Type: Grant
    Filed: September 9, 1998
    Date of Patent: May 17, 2005
    Assignee: Biotecon Diagnostics GmbH
    Inventors: Cornelia Berghof, Alexander Gasch, Anja Braeuer, Cordt Groenewald, Freimut Wilborn, Arndt Rolfs
  • AMINO ACID SEQUENCES AND METHOD FOR ISOLATING BACTERIES FROM THE TYPE GENUS PSEUDOMONAS
    Publication number: 20030082656
    Abstract: The present invention relates to a nucleic acid molecule or molecules and to a process for the detection of bacteria of the Pseudomonas genus, especially Pseudomonas aeruginosa. The invention relates also to a test kit or kits for carrying out the said detection processes.
    Type: Application
    Filed: May 8, 2000
    Publication date: May 1, 2003
    Inventors: CORNELIA BERGHOF, ALEXANDER GASCH, ANJA BRAEUER, CORDT GROENEWALD, FREIMUT WILBORN, ARNDT ROLFS
  • Genus and species-specific identification of Legionella
    Patent number: 6194145
    Abstract: Method for the genus-specific amplification of legionella and genus-specific or species-specific identification.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: February 27, 2001
    Assignee: Roche Diagnostics GmbH
    Inventors: Björn Heidrich, Peter-Nicholas Robinson, Frank Tiecke, Arndt Rolfs
  • Process for reducing the formation of artifacts during transcription of ribonucleic acids to deoxynucleic acids
    Patent number: 6124093
    Abstract: A method of transcribing ribonucleic acids of a sample by treating the sample containing ribonucleic acid with a DNA digesting enzyme in the presence of Mn.sup.2+ ions followed by transcribing the ribonucleic acids into deoxyribonucleic acids and suitable reagents.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: September 26, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Peter Bauer, Arndt Rolfs, Vera Regitz-Zagrosek, Eckart Fleck