Patents by Inventor Arul Chinnaiyan

Arul Chinnaiyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RAF gene fusions
    Patent number: 8945556
    Abstract: The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to RAF gene fusions as diagnostic markers and clinical targets for cancer.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: February 3, 2015
    Assignee: The Regents of The University of Michigan
    Inventors: Arul Chinnaiyan, Nallasivam Palanisamy, Shanker Kalyana-Sundaram
  • RECURRENT GENE FUSIONS IN CANCER
    Publication number: 20150017637
    Abstract: The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to gene fusions as diagnostic markers and clinical targets for cancer.
    Type: Application
    Filed: July 11, 2014
    Publication date: January 15, 2015
    Inventors: Arul Chinnaiyan, Yi-Mi Wu, Dan Robinson
  • RNA CHIMERAS IN HUMAN LEUKEMIA AND LYMPHOMA
    Publication number: 20140364481
    Abstract: Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent RNA fusions as diagnostic markers and clinical targets for leukemia.
    Type: Application
    Filed: May 6, 2014
    Publication date: December 11, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Kojo Elenitoba-Johnson, Thirunavukkarasu Velusamy, Nallasivam Palanisamy, Anagh Sahasrabuddhe, Megan Lim, Arul Chinnaiyan
  • BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
    Publication number: 20140256706
    Abstract: Inhibitors of BET bromodomains and compositions containing the same are disclosed. Methods of using the BET bromodomain inhibitors in the treatment of diseases and conditions wherein inhibition of BET bromodomain provides a benefit, like cancers, also are disclosed.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 11, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Shaomeng Wang, Xu Ran, Yujun Zhao, Chao-Yie Yang, Liu Liu, Longchuan Bai, Donna McEachern, Jeanne Stuckey, Jennifer Lynn Meagher, Duxin Sun, Xiaoqin Li, Bing Zhou, Hacer Karatas, Ruijuan Luo, Arul Chinnaiyan, Irfan A. Asangani
  • RECURRENT GENE FUSIONS IN HEMANGIOPERICYTOMA
    Publication number: 20140178871
    Abstract: Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions as diagnostic markers and clinical targets for hemangiopericytoma.
    Type: Application
    Filed: August 8, 2013
    Publication date: June 26, 2014
    Inventors: Arul Chinnaiyan, Dan Robinson
  • Methods and compositions for diagnosing prostate cancer
    Patent number: 8617547
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: December 31, 2013
    Assignee: The Regents of The University of Michigan
    Inventors: Arul Chinnaiyan, David Beer, Guoan Chen, Xiaoju Wang
  • Recurrent gene fusions in prostate cancer
    Patent number: 8580509
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: November 12, 2013
    Assignees: The Regents of The University of Michigan, The Brigham and Women's Hospital, Inc.
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • ncRNA AND USES THEREOF
    Publication number: 20130267443
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer.
    Type: Application
    Filed: March 12, 2013
    Publication date: October 10, 2013
    Applicant: The Regents of the University of Michigan
    Inventors: Arul Chinnaiyan, John Prensner, Matthew Iyer
  • RECURRENT GENE FUSIONS IN PROSTATE CANCER
    Publication number: 20130040858
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Application
    Filed: May 30, 2012
    Publication date: February 14, 2013
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • RECURRENT GENE FUSIONS IN PROSTATE CANCER
    Publication number: 20120295809
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Application
    Filed: May 30, 2012
    Publication date: November 22, 2012
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • RECURRENT GENE FUSIONS IN PROSTATE CANCER
    Publication number: 20120296070
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Application
    Filed: May 30, 2012
    Publication date: November 22, 2012
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • Recurrent gene fusions in prostate cancer
    Patent number: 8211645
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: July 3, 2012
    Assignees: The Regents of the University of Michigan, The Brigham and Women's Hospital
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • RAF GENE FUSIONS
    Publication number: 20120142549
    Abstract: The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to RAF gene fusions as diagnostic markers and clinical targets for cancer.
    Type: Application
    Filed: November 18, 2011
    Publication date: June 7, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul Chinnaiyan, Nallasivam Palanisamy, Shanker Kalyana-Sundaram
  • PHAGE MICROARRAY PROFILING OF THE HUMORAL RESPONSE TO DISEASE
    Publication number: 20110070652
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
    Type: Application
    Filed: October 28, 2010
    Publication date: March 24, 2011
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: ARUL CHINNAIYAN, XIAOJU WANG
  • RECURRENT GENE FUSIONS IN PROSTATE CANCER
    Publication number: 20110034677
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Application
    Filed: December 30, 2009
    Publication date: February 10, 2011
    Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • Phage microarray profiling of the humoral response to disease
    Patent number: 7858323
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: December 28, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: Arul Chinnaiyan, Xiaoju Wang
  • METHODS AND COMPOSITIONS FOR DIAGNOSING BLADDER CANCER
    Publication number: 20100279301
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to genes and gene panels as diagnostic markers and clinical targets for bladder cancer. Methods, compositions, and kits for diagnosing, determining, and determining risk of tumor aggressiveness are disclosed.
    Type: Application
    Filed: May 3, 2010
    Publication date: November 4, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul Chinnaiyan, Rou Wang, David Morris, Scott Tomlins
  • Recurrent gene fusions in prostate cancer
    Patent number: 7718369
    Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Grant
    Filed: September 12, 2006
    Date of Patent: May 18, 2010
    Assignees: The Regents of the University of Michigan, The Brigham and Women's Hospital, Inc.
    Inventors: Scott Tomlins, Daniel Rhodes, Arul Chinnaiyan, Rohit Mehra, Mark A. Rubin, Xiao-Wei Sun, Sven Perner, Charles Lee, Francesca Demichelis
  • METHODS AND COMPOSITIONS FOR DIAGNOSING LUNG CANCER
    Publication number: 20100009382
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
    Type: Application
    Filed: September 10, 2009
    Publication date: January 14, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul Chinnaiyan, David Beer, Guoan Chen, Xiaoju Wang
  • Methods and compositions for diagnosing lung cancer
    Patent number: 7597890
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: October 6, 2009
    Assignee: The Regents of the University of Michigan
    Inventors: Arul Chinnaiyan, David Beer, Guoan Chen, Xiaoju Wang