Patents by Inventor Asaph Aharoni

Asaph Aharoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9909135
    Abstract: The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: March 6, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Gad Galili, Asaph Aharoni, Vered Tzin, Sergey Malitsky, Ilana Rogachev
  • Publication number: 20160122775
    Abstract: The present invention relates to genetically modified plants by key genes involved in the biosynthesis of steroidal alkaloids. These plants have altered content of steroidal (glyco)alkaloids. Solanaceous crop plants with reduced content of antinutritional steroidal glycoalkaloids are provided.
    Type: Application
    Filed: June 2, 2014
    Publication date: May 5, 2016
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Asaph AHARONI, Maxim ITKIN
  • Patent number: 8940961
    Abstract: Transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants having integrated in their genome a chimeric gene, wherein the chimeric gene includes a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3 or an ortholog or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure. Also, a method for generating a transgenic plant by insertion of the chimeric gene.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: January 27, 2015
    Assignee: Stiching Dienst Landbouwkundig Onderzoek
    Inventors: Asaph Aharoni, Shital Dixit, Kurniawan Rudi Trijatmiko, Jelle Hiemstra, Andy Pereira
  • Publication number: 20130198900
    Abstract: The present invention provides bioengineered organisms producing elevated levels of thiamine and/or thiamine derivatives. Particularly, the present invention discloses that modifying TPP-responsive riboswitch results in accumulation of thiamine and/or its derivatives.
    Type: Application
    Filed: September 7, 2011
    Publication date: August 1, 2013
    Applicants: BEN-GURION UNIVERSITY OF THE NEGEV, YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Asaph Aharoni, Samuel Bocobza, Michal Shapira
  • Publication number: 20130111631
    Abstract: The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.
    Type: Application
    Filed: July 6, 2011
    Publication date: May 2, 2013
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Gad Galili, Asaph Aharoni, Vered Tzin, Sergey Malitsky, Ilana Rogachev
  • Patent number: 8338663
    Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: December 25, 2012
    Assignee: Monsanto Invest N.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
  • Publication number: 20120278949
    Abstract: The present invention relates to the field of transgenic plants with novel phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring novel phenotypes to plants.
    Type: Application
    Filed: July 6, 2012
    Publication date: November 1, 2012
    Applicant: Stichting Dienst Landbouwkundig Onderzoek
    Inventors: Asaph AHARONI, Chital Dixit, Andy Pereira
  • Patent number: 8252978
    Abstract: The present invention relates to the field of transgenic plants with given phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring these phenotypes to plants.
    Type: Grant
    Filed: June 9, 2005
    Date of Patent: August 28, 2012
    Assignee: Stichting Dienst Landbouwkundig Onderzoek
    Inventors: Asaph Aharoni, Chital Dixit, Andy Pereira
  • Publication number: 20110209247
    Abstract: The present invention relates to the field of transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants comprising integrated in their genome a chimeric gene, characterized by said chimeric gene comprising a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3, or an ortholog protein or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure.
    Type: Application
    Filed: September 6, 2005
    Publication date: August 25, 2011
    Inventors: Asaph Aharoni, Shital Dixit, Kurniawan Rudi Trijatmiko, Jelle Hiemstra, Andy Pereira
  • Publication number: 20110093986
    Abstract: The present invention discloses that down regulation of the SlMYB12 transcription factor results in the colorless peel y phenotype in tomato fruit. The present invention provides polynucleotides encoding the tomato SlMYB12 transcription factor and genetic markers derived therefrom, useful in the breeding of tomato plants having the colorless peel phenotype and in the production of transgenic plants having altered flavonoid content.
    Type: Application
    Filed: June 28, 2009
    Publication date: April 21, 2011
    Applicant: Yeda Research and Development Co., Ltd At The Weizmann Institute of Science
    Inventors: Asaph Aharoni, Avital Adato, Tali Mandel
  • Publication number: 20100281567
    Abstract: The present invention relates to means and methods for altering the level of at least one of the aromatic amino acids phenylalanine, tryptophan and tyrosine and secondary metabolites in plants. Particularly, the present invention discloses transgenic plants comprising polynucleotides encoding chorismate mutase and prephenate dehydratase enzymes, having elevated amounts of at least one of phenylalanine, tyrosine and modified amount of at least one secondary metabolite derived therefrom, and reduced amount of tryptophan and at least one secondary metabolite derived from tryptophan.
    Type: Application
    Filed: December 3, 2008
    Publication date: November 4, 2010
    Inventors: Gad Galili, Vered Tzin, Asaph Aharoni, Sergey Malitsky
  • Publication number: 20100144893
    Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
    Type: Application
    Filed: November 17, 2008
    Publication date: June 10, 2010
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
  • Publication number: 20090300790
    Abstract: The present invention relates to the field of transgenic plants with given phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring these phenotypes to plants.
    Type: Application
    Filed: June 9, 2005
    Publication date: December 3, 2009
    Inventors: Asaph Aharoni, Chital Dixit, Andy Pereira
  • Publication number: 20090049568
    Abstract: A method to prevent dehiscence in a plant or to alter plant lignification including providing the plant with a nucleotide protein coding for a GGL protein or a functional equivalent thereof, and growing the plant. Also, the isolated GGL protein or functional equivalents, a nucleic acid encoding the protein and vectors, host cells and plants including the nucleic acid.
    Type: Application
    Filed: July 28, 2005
    Publication date: February 19, 2009
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Andy Pereira
  • Publication number: 20090031455
    Abstract: The present invention provides a novel cytochrome P450 enzyme, as well as vectors and recombinant host cells comprising the gene encoding the enzyme. Provided are recombinant plant with enhanced disease and/or pest resistance, modified favour and/or fragrance and methods for hydroxy lifting terpene substrates.
    Type: Application
    Filed: October 14, 2005
    Publication date: January 29, 2009
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Hendrik Jan Bouwmeester
  • Patent number: 7453024
    Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: November 18, 2008
    Assignees: De Ruiter Seeds R&D B.V., Enza Zaden Beheer B.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
  • Publication number: 20040161819
    Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
    Type: Application
    Filed: August 5, 2003
    Publication date: August 19, 2004
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Andrianus Verhoeven, Hendrik Jan Bouwmeester