Patents by Inventor Asaph Aharoni
Asaph Aharoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9909135Abstract: The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.Type: GrantFiled: July 6, 2011Date of Patent: March 6, 2018Assignee: Yeda Research and Development Co. Ltd.Inventors: Gad Galili, Asaph Aharoni, Vered Tzin, Sergey Malitsky, Ilana Rogachev
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Publication number: 20160122775Abstract: The present invention relates to genetically modified plants by key genes involved in the biosynthesis of steroidal alkaloids. These plants have altered content of steroidal (glyco)alkaloids. Solanaceous crop plants with reduced content of antinutritional steroidal glycoalkaloids are provided.Type: ApplicationFiled: June 2, 2014Publication date: May 5, 2016Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.Inventors: Asaph AHARONI, Maxim ITKIN
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Patent number: 8940961Abstract: Transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants having integrated in their genome a chimeric gene, wherein the chimeric gene includes a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3 or an ortholog or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure. Also, a method for generating a transgenic plant by insertion of the chimeric gene.Type: GrantFiled: September 6, 2005Date of Patent: January 27, 2015Assignee: Stiching Dienst Landbouwkundig OnderzoekInventors: Asaph Aharoni, Shital Dixit, Kurniawan Rudi Trijatmiko, Jelle Hiemstra, Andy Pereira
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Publication number: 20130198900Abstract: The present invention provides bioengineered organisms producing elevated levels of thiamine and/or thiamine derivatives. Particularly, the present invention discloses that modifying TPP-responsive riboswitch results in accumulation of thiamine and/or its derivatives.Type: ApplicationFiled: September 7, 2011Publication date: August 1, 2013Applicants: BEN-GURION UNIVERSITY OF THE NEGEV, YEDA RESEARCH AND DEVELOPMENT CO. LTD.Inventors: Asaph Aharoni, Samuel Bocobza, Michal Shapira
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Publication number: 20130111631Abstract: The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback inhibition, particularly to feedback inhibition by phenylalanine, producing increased amounts of the Shikimate pathway primary and secondary metabolites, including aromatic amino acids compared to corresponding non-transgenic plants.Type: ApplicationFiled: July 6, 2011Publication date: May 2, 2013Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.Inventors: Gad Galili, Asaph Aharoni, Vered Tzin, Sergey Malitsky, Ilana Rogachev
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Patent number: 8338663Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.Type: GrantFiled: November 17, 2008Date of Patent: December 25, 2012Assignee: Monsanto Invest N.V.Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
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Publication number: 20120278949Abstract: The present invention relates to the field of transgenic plants with novel phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring novel phenotypes to plants.Type: ApplicationFiled: July 6, 2012Publication date: November 1, 2012Applicant: Stichting Dienst Landbouwkundig OnderzoekInventors: Asaph AHARONI, Chital Dixit, Andy Pereira
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Patent number: 8252978Abstract: The present invention relates to the field of transgenic plants with given phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring these phenotypes to plants.Type: GrantFiled: June 9, 2005Date of Patent: August 28, 2012Assignee: Stichting Dienst Landbouwkundig OnderzoekInventors: Asaph Aharoni, Chital Dixit, Andy Pereira
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Publication number: 20110209247Abstract: The present invention relates to the field of transgenic plants with novel phenotypes, especially plants with enhanced drought and pathogen resistance. Provided are transgenic crop plants comprising integrated in their genome a chimeric gene, characterized by said chimeric gene comprising a transcription regulatory sequence active in plant cells operably linked to a nucleic acid sequence encoding a protein having the sequence of SEQ ID NO: 3 or a protein at least 70% identical to SEQ ID NO: 3, or an ortholog protein or a functional fragment thereof. In addition to enhanced drought tolerance the transgenic plants may show enhanced disease resistance and enhanced root structure.Type: ApplicationFiled: September 6, 2005Publication date: August 25, 2011Inventors: Asaph Aharoni, Shital Dixit, Kurniawan Rudi Trijatmiko, Jelle Hiemstra, Andy Pereira
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Publication number: 20110093986Abstract: The present invention discloses that down regulation of the SlMYB12 transcription factor results in the colorless peel y phenotype in tomato fruit. The present invention provides polynucleotides encoding the tomato SlMYB12 transcription factor and genetic markers derived therefrom, useful in the breeding of tomato plants having the colorless peel phenotype and in the production of transgenic plants having altered flavonoid content.Type: ApplicationFiled: June 28, 2009Publication date: April 21, 2011Applicant: Yeda Research and Development Co., Ltd At The Weizmann Institute of ScienceInventors: Asaph Aharoni, Avital Adato, Tali Mandel
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Publication number: 20100281567Abstract: The present invention relates to means and methods for altering the level of at least one of the aromatic amino acids phenylalanine, tryptophan and tyrosine and secondary metabolites in plants. Particularly, the present invention discloses transgenic plants comprising polynucleotides encoding chorismate mutase and prephenate dehydratase enzymes, having elevated amounts of at least one of phenylalanine, tyrosine and modified amount of at least one secondary metabolite derived therefrom, and reduced amount of tryptophan and at least one secondary metabolite derived from tryptophan.Type: ApplicationFiled: December 3, 2008Publication date: November 4, 2010Inventors: Gad Galili, Vered Tzin, Asaph Aharoni, Sergey Malitsky
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Publication number: 20100144893Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and biocontrol agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.Type: ApplicationFiled: November 17, 2008Publication date: June 10, 2010Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
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Publication number: 20090300790Abstract: The present invention relates to the field of transgenic plants with given phenotypes, especially plants with enhanced drought tolerance. Provided are SHINE proteins and nucleic acid sequences encoding these, which are useful in conferring these phenotypes to plants.Type: ApplicationFiled: June 9, 2005Publication date: December 3, 2009Inventors: Asaph Aharoni, Chital Dixit, Andy Pereira
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Publication number: 20090049568Abstract: A method to prevent dehiscence in a plant or to alter plant lignification including providing the plant with a nucleotide protein coding for a GGL protein or a functional equivalent thereof, and growing the plant. Also, the isolated GGL protein or functional equivalents, a nucleic acid encoding the protein and vectors, host cells and plants including the nucleic acid.Type: ApplicationFiled: July 28, 2005Publication date: February 19, 2009Applicant: PLANT RESEARCH INTERNATIONAL B.V.Inventors: Asaph Aharoni, Andy Pereira
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Publication number: 20090031455Abstract: The present invention provides a novel cytochrome P450 enzyme, as well as vectors and recombinant host cells comprising the gene encoding the enzyme. Provided are recombinant plant with enhanced disease and/or pest resistance, modified favour and/or fragrance and methods for hydroxy lifting terpene substrates.Type: ApplicationFiled: October 14, 2005Publication date: January 29, 2009Applicant: PLANT RESEARCH INTERNATIONAL B.V.Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Hendrik Jan Bouwmeester
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Patent number: 7453024Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.Type: GrantFiled: August 5, 2003Date of Patent: November 18, 2008Assignees: De Ruiter Seeds R&D B.V., Enza Zaden Beheer B.V.Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Adrianus Verhoeven, Hendrik Jan Bouwmeester
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Publication number: 20040161819Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.Type: ApplicationFiled: August 5, 2003Publication date: August 19, 2004Applicant: PLANT RESEARCH INTERNATIONAL B.V.Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Andrianus Verhoeven, Hendrik Jan Bouwmeester