Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: Systems and methods to provide an interactive environment over an expanded field-of-view are presented herein. The system may include one or more of a headset, a first image forming component held by the headset, a second image forming component held by the headset, one or more physical processors, and/or other components. The first image forming component may be configured to generate light rays to form a first set of images of virtual content at a first resolution. The first set of images of virtual content may be presented to the user over a first angular portion of the user's field-of-view. The second image forming component may be configured to generate light rays to form a second set of images of virtual content at a second resolution. The second set of images of virtual content may be presented to the user over a second angular portion of the user's field-of-view.

Abstract: Aspects of the disclosed apparatuses, methods, and systems provide a wearable, augmented or virtual reality display system including two or more sets of backlight illumination arrangements. Each different set of backlight illumination is directed to a corresponding optical imaging system. The corresponding optical imaging system is designed to focus each set of illumination at a different distance. The selection of a particular optical focal distance is controlled by selecting the set of backlight illumination corresponding to the imaging system to provide the desired focal distance. As a result, selection of the backlight illumination determines at which distance an image is perceived by a user. When multiple backlight illumination sets are multiplexed with 2-D images, a single, 3-D image is perceived by the wearer of the display system.

Abstract: In one general aspect, an optical system for a head mounted display system is provided. The optical system includes an image source and an optical component. The optical component includes a reflective surface configured to receive an image from the image source, the optical component having a specified curvature that reflects and presents the image to a user of the head mounted display.

Abstract: A system configured for providing views of virtual content in an augmented reality environment may comprise one or more of a first display, a second display, an optical element, one or more processors, and/or other components. The first display and second display may be separated by a separation distance. The first display and second display may be arranged such that rays of light emitted from pixels of the first display may travel through the second display, then reflect off the optical element and into a user's eyes. A three-dimensional light field perceived with a user's field-of-view may be generated. Distances of the first display and/or second display to the optical element may impact a perceived range of the three-dimensional light field. The separation distance may impact a perceived depth of the three-dimensional light field and/or a resolution of virtual content perceived with the three-dimensional light field.

Abstract: A system configured for providing views of virtual content in an augmented reality environment may comprise one or more of a first display, a second display, an optical element, one or more processors, and/or other components. The first display and second display may be separated by a separation distance. The first display and second display may be arranged such that rays of light emitted from pixels of the first display may travel through the second display, then reflect off the optical element and into a user's eyes. A three-dimensional light field perceived with a user's field-of-view may be generated. Distances of the first display and/or second display to the optical element may impact a perceived range of the three-dimensional light field. The separation distance may impact a perceived depth of the three-dimensional light field and/or a resolution of virtual content perceived with the three-dimensional light field.

Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.

Abstract: In one general aspect, an optical system for a head mounted display system is provided. The optical system includes an image source and an optical component. The optical component includes a reflective surface configured to receive an image from the image source, the optical component having a specified curvature that reflects and presents the image to a user of the head mounted display.

Abstract: Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.

Abstract: Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.

Abstract: Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.

Abstract: The present invention is an improved method of electrically stimulating percepts in a patient with a visual prosthesis, to induce a more controlled perception of light. In particular, the present invention is an improved electrode array to maximize retinal response. The array of the present invention is an array with a center section with no electrode, surrounded by a ring of small high density electrodes. Electrodes beyond to ring are gradually larger and more widely spaced.

Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: Disclosed herein are instruments and methods for delivery of substrates, including cell-seeded substrates, to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: The present invention is an improved method of electrically stimulating percepts in a patient with a visual prosthesis, to induce a more controlled perception of light. In particular, the present invention is an improved electrode array to maximize retinal response. The array of the present invention is an array with a center section with no electrode, surrounded by a ring of small high density electrodes. Electrodes beyond to ring are gradually larger and more widely spaced.

Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.