Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.

Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: Present implementations include an electronic device with a system processor (SP) region connectable to an SP, a primary device region connectable to a first electronic device, and a secondary device region disposed between the SP device region and the primary device region, and connectable to a second electronic device. Present implementations further include a debugger region including a debugger unit and disposed adjacent to the primary device region and the secondary device region.

Abstract: Present implementations include an electronic device with a system processor (SP) region connectable to an SP, a primary device region connectable to a first electronic device, and a secondary device region disposed between the SP device region and the primary device region, and connectable to a second electronic device. Present implementations further include a debugger region including a debugger unit and disposed adjacent to the primary device region and the secondary device region.

Abstract: Aspects of the disclosed apparatuses, methods, and systems provide arrangement of the visual components of an augmented or virtual display system with optimized telecentricity, focal depth, and wide FOV. The visual components may include a light source and a corresponding optical element.

Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.

Abstract: Described herein are systems and methods to provide privacy protection and brightness enhancement in an interactive environment. A system may include one or more of a headset, one or more light sources, one or more optical elements, one or more physical processor, and/or other components. A light source may be configured to generate linearly polarized light rays polarized on a first polarization plane along an axis of propagation. A reflective polarizer of an optical element may be configured to transmit light rays polarized on a second polarization plane transverse to the first polarization plane. Light rays polarized along the first polarization plane may be reflected off the reflective polarizer. An absorptive polarizer of an optical element may transmit light rays polarized on the second polarization plane so that light rays polarized along the second polarization plane may be transmitted through both the absorptive polarizer and the reflective polarizer.

Abstract: Systems and methods of image projection are presented herein. Image projection may be facilitated by a layered waveguide and/or other components. The layered waveguide may have an input portion and a presentation portion. Light may be received from a display at the input portion and output at the presentation portion. Th input portion may include coupling optical features. The presentation portion ma include presentation optical features forming Bragg diffraction gratings. Relative proportions of light emitted by the display and coupled onto the layers may be controlled adjust a cumulative focal length of the layered waveguide.

Abstract: Aspects of the disclosed apparatuses, methods and systems provide a wearable, augmented or virtual reality display system including two or more sets of backlight illumination arrangements. Each different set of backlight illumination is directed to a corresponding optical imaging system. The corresponding optical imaging system is designed to focus each set of illumination at a different distance. The selection of a particular optical focal distance is controlled by selecting the set of backlight illumination corresponding to the imaging system to provide the desired focal distance. As a result, selection of the backlight illumination determines at which distance an image is perceived by a user. When multiple backlight illumination sets are multiplexed with 2-D images, a single, 3-D image is perceived by the wearer of the display system.

Abstract: Aspects of the disclosed apparatuses, methods, and systems provide enhanced display of images for personal wearable display devices. The display systems include various system components to implement one or more of: re-directing the maximal brightness of a display device towards the center of the eye-box of a user; selectively narrowing the viewing angle of light emitted by the display device; and by spatially optimizing the backlight of the display device based on the specification of the wearable optical system thereby optimizing and/or maximizing the amount of light entering the eye for a range of gaze rotation of a user of the wearable display system. In one example, the following description provides a display device including a light optimizing or directing layer. The light optimizing layer includes one or more films that optimize the amount of light directed to the eye box of a user of the wearable display system.

Abstract: Systems and methods to provide an interactive environment over an expanded field-of-view are presented herein. The system may include one or more of a headset, a first image forming component held by the headset, a second image forming component held by the headset, one or more physical processors, and/or other components. The first image forming component may be configured to generate light rays to form a first set of images of virtual content at a first resolution. The first set of images of virtual content may be presented to the user over a first angular portion of the user's field-of-view. The second image forming component may be configured to generate light rays to form a second set of images of virtual content at a second resolution. The second set of images of virtual content may be presented to the user over a second angular portion of the user's field-of-view.

Abstract: Disclosed herein are instruments and methods for delivery of substrates, including cell-seeded substrates, to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: A system to provide views of virtual content in an interactive space, e.g., an augmented reality environment, may comprise one or more of a light source, directional control device, variable power lens, beam steering device, optical element, and/or one or more physical processors. A light source may generate collimated light rays in accordance with virtual content to be perceived within a three-dimensional light field. A directional control device may controllable adjust direction of travel of collimated light rays toward a beam steering device. A variable power lens may be positioned to receive collimated light rays between a light source and a directional control device. A beam steering device may be configured to direct collimated light rays to locations on an optical element. An optical element may be configured to reflect collimated light rays in a focal plane of a perceived three-dimensional light field.

Abstract: Disclosed herein are methods and compositions for the cryopreservation of stem cells, such as stem-cell derived retinal pigment epithelial cells, that have been seeded onto and cultured on a substrate, such as a polymeric substrate. Such cryopreserved stem cells are useful for cell therapies, such as treatment of ocular damage or disease.

Abstract: Aspects of the disclosed apparatuses, methods and systems provide coating profiles for optics of a stereoscopic vision system configured to reduce unwanted light. Offset masks are used to provide gradient coating thicknesses. A method of forming the optical system with coatings and mechanical holder used during the method also are provided.

Abstract: Systems and methods to provide an interactive space over an expanded field-of-view with focal distance tuning are presented herein. The system may include one or more of a headset, a first image forming component, a second image forming component, a set of tuning components, one or more physical processors, and/or other components. The first image forming component may be configured to generate light rays to form a first set of images presented over a first angular portion of a user's field-of-view. The second image forming component may be configured to generate light rays to form a second set of images of virtual content presented over a second angular portion of the user's field-of-view. A vergence distance of a gaze of a user may be determined. A focal distance of the images may be adjusted to match the vergence distance.

Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: Systems and methods to provide an interactive space over an expanded field-of-view with focal distance tuning are presented herein. The system may include one or more of a headset, a first image forming component, a second image forming component, a set of tuning components, one or more physical processors, and/or other components. The first image forming component may be configured to generate light rays to form a first set of images presented over a first angular portion of a user's field-of-view. The second image forming component may be configured to generate light rays to form a second set of images of virtual content presented over a second angular portion of the user's field-of-view. A vergence distance of a gaze of a user may be determined. A focal distance of the images may be adjusted to match the vergence distance.

Abstract: Disclosed herein are generally to methods and systems that facilitate imaging of cells on a substrate and more particularly to pre-implantation (in vitro) and post-implantation (in vivo) imaging of cell-seeded substrates implanted in target tissues in the context of stem cell therapy.

Abstract: Systems and methods to provide an interactive environment over an expanded field-of-view are presented herein. The system may include one or more of a headset, a first image forming component held by the headset, a second image forming component held by the headset, one or more physical processors, and/or other components. The first image forming component may be configured to generate light rays to form a first set of images of virtual content at a first resolution. The first set of images of virtual content may be presented to the user over a first angular portion of the user's field-of-view. The second image forming component may be configured to generate light rays to form a second set of images of virtual content at a second resolution. The second set of images of virtual content may be presented to the user over a second angular portion of the user's field-of-view.