Abstract: Multi-layer solid oral dosage immediate release and extended release compositions and methods for delivering drugs in abnormally high pH environments wherein the extended release layer is formed from a drug resinate of a strong acid ion-exchange resin and a release rate retarding polymer compressed together.

Abstract: The invention provides a film comprising at least two layers, a first layer and a second layer; and wherein the first layer is formed from a first composition comprising a polyester, a polylactic acid, or a combination thereof; and wherein the second layer is formed from a second composition comprising at least the following: A) functionalized ethylene-based polymer, and B) ethylene/alpha-olefin interpolymer; and wherein the first layer is adjacent to the second layer.

Abstract: Methods, apparatuses, and devices are described for wireless communications in which neighborhood area network (NaN) information may be requested and provided in a relatively fast and efficient manner between devices of a NaN. A wireless communication device, such as a station in a wireless communications network, may transmit an active probe request to seek information related to a NaN. The active probe request may be a NaN specific probe request, or may be transmitted from a station as part of an active scan for wireless network infrastructure other than NaN devices (e.g., as part of a scan for an AP in a BSS). An AP or master device of the NaN may receive the probe request and generate a NaN discovery response, which may include information that the requesting device may use for connecting to a device in the NaN.

Abstract: A system, method and computer readable medium for targeting messages delivered by wireless communication comprising determining at least one target space within at least one wireless communications network, determining a notification list comprising at least one recipient in said at least one target space, determining at least one notification message, and transmitting said at least one notification message through said at least one wireless communications network to at least one recipient on said notification list.

Abstract: Methods and systems disclosed in the current application are directed to efficient distribution of resource-availability information with respect to individual computer systems within a distributed computer system in order to facilitate various types of computational tasks, including configuration and management tasks and facilities. Certain of these implementations are based on highly efficient, lockless, message-based information-distribution methods and subsystems that transmission of messages at a frequency computed from a computed level of resource availability.

Abstract: A method for calculating the effect of an action on a network includes creating a mapping of a plurality of devices of a networked computing environment. In one embodiment, the mapping describes a relationship between a primary device and at least one device of the plurality of devices. In another embodiment, the method includes determining a plurality of potential actions to be performed on the primary device. In a further embodiment, the method includes calculating an effect of a potential action of the plurality of potential actions on the plurality of devices in response to simulating performing the potential action on the primary device. In yet another embodiment, the method includes performing an optimization action in response to calculating the effect of the potential action. In certain embodiments, the optimization action maximizes availability of the networked computing environment.

Abstract: A multi-threaded binary translation system performs atomic operations by a thread, such operations include processing a load linked instruction and a store conditional instruction. The store conditional instruction updates data stored in a shared memory address only when at least three conditions are satisfied. The conditions are: a copy of a load linked shared memory address of the load linked instruction is the same as the store conditional shared memory address, a reservation flag indicates that the thread has a valid reservation, and the copy of data stored by the load linked instruction is the same as data stored in the store conditional shared memory address.

Abstract: Disclosed herein are substrates for cell delivery to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide seeded cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.

Abstract: The present disclosure provides a method, non-transitory computer-readable storage medium, and computer system that implement a latency monitoring and reporting service configured to collect and report latency of service transactions. In one embodiment, a chronicler object is generated and transmitted to a charging engine, where the chronicler object is configured to collect a set of time points as the chronicler object travels through one or more components of the charging engine. Upon return of the chronicler object, the set of time points is extracted from the chronicler object and added to one of a plurality of accumulator objects. Each accumulator object includes a plurality of sets of time points from a plurality of chronicler objects that are received during a reporting window. The plurality of sets of times points of each accumulator object is used to calculate the latency of service transactions.

Abstract: An apparatus for calculating the effect of an action on a network includes a mapping module that creates a mapping of a plurality of devices of a networked computing environment. The mapping describes a relationship between a primary device and at least one device of the plurality of devices. The apparatus includes an action module that determines a plurality of potential actions to be performed on the primary device. The apparatus includes a calculation module that calculates an effect of a potential action of the plurality of potential actions on the plurality of devices in response to simulating performing the potential action on the primary device. The apparatus includes an optimization module that performs an optimization action in response to calculating the effect of the potential action. The optimization action maximizes availability of the networked computing environment.

Abstract: Among other things, one or more techniques and/or systems are provided for storing data within a hybrid storage aggregate comprising a lower-latency storage tier and a higher-latency storage tier. In particular, frequently accessed data, randomly accessed data, and/or short lived data may be stored (e.g., read caching and/or write caching) within the lower-latency storage tier. Infrequently accessed data and/or sequentially accessed data may be stored within the higher-latency storage tier. Because the hybrid storage aggregate may comprise a single logical container derived from the higher-latency storage tier and the lower-latency storage tier, additional storage and/or file system functionality may be implemented across the storage tiers. For example, deduplication functionality, caching functionality, backup/restore functionality, and/or other functionality may be provided through a single file system (or other type of arrangement) and/or a cache map implemented within the hybrid storage aggregate.

Abstract: Disclosed are oil-extended olefin block copolymer compositions with microcrystalline wax. The microcrystalline wax reduces oil-bleed while maintaining composition softness.

Abstract: It is determined that a first data block contains the same data as a second data block. The first data block is associated with a first extent and the second data block is associated with a second extent. In response to determining that the first data block contains the same data as the second data block, the second data block is associated with the first extent and the first data block is disassociated with the second extent.

Abstract: An apparatus comprises: a sensing element formed on a buried oxide layer of a substrate and providing communication between a source region and a drain region; a gate dielectric layer on the sensing element, the gate dielectric layer defining a sensing surface on the sensing element; a passive surface surrounding the sensing surface; and a compound bound to the sensing surface and not bound to the passive surface, the compound having a ligand specifically configured to preferentially bind a target molecule to be sensed. An electrolyte solution in contact with the sensing surface and the passive surface forms a top gate of the apparatus.

Abstract: A computer system is described for providing intervention suggestion information to a user, for the purpose of changing a psychological state of the user. The information suggestion information identifies at least one recommended intervention, selected from a pool of candidate interventions. Each candidate intervention, in turn, involves a type of computer-related activity with which the user is likely already familiar. The computer system formulates the intervention suggestion information in the form of one or more messages, delivered to one or more user devices, such as a mobile user device, or a mobile user device in conjunction with an ambient presentation device. According to one optional aspect, the computer system chooses the recommended interventions based on context information. According to another aspect, the computer system selects interventions by adopting a particular balance between an exploitation mode and an exploration mode.

Abstract: Pharmaceutical compositions of metabotropic glutamate 5 receptor (mGlu5) antagonists or a pharmacologically acceptable salt thereof are disclosed. The compositions contain the therapeutic active compound with non-ionic polymer and ionic polymer, binder and fillers in either matrix pellet, matrix tablet or coated pellets. The compositions provide a pH-independent in vitro release profile with NMT 70% in one hour, NMT 85% in 4 hour, and NLT 80% in 8 hours. The compositions are useful for the treatment of CNS disorders, such as Treatment-Resistant Depression (TRD) and Fragile X Syndrome.

Abstract: A first notification of a first action by a user with respect to a first content item may be received by a computer system, the first content item having a first relationship to the user. A second notification of a second notification by the user with respect to a second content item may be received by the computer system. The second content item may have a second relationship to the user, and at least a portion of the second content item may correspond to at least a portion of the first content item. A first property of the first relationship may be managed by the computer system based on the second notification.

Abstract: An improved technique of organizing content of online meetings involves generating an electronic summary based on a textual metadata derived from content presented in an online meeting. An online meeting server collects content such as audio, video, and slide files presented in a particular online meeting. From metadata associated with such content, the online meeting server generates an electronic summary of the particular online meeting which includes a textual description of the content. The online meeting server then stores the electronic summary and the content presented in the particular online meeting in a repository that is configured to store content from other online meetings.

Abstract: Systems and methods disclosed herein may include tracking one or more geo-fences using a GNSS hardware processor within a computing device. The tracking may use at least one GNSS signal. State changes of the one or more geo-fences during the tracking may be saved in a shared state database. The shared state database may be shared between the GNSS hardware processor and an application processor within the computing device. Upon detecting a deterioration of the at least one GNSS signal, tracking the one or more geo-fences may be switched from using the GNSS hardware processor to using the application processor. After the switching, an initial state of each of the one or more geo-fences may be set by using states currently stored in the shared state database prior to the switching.

Abstract: Systems and methods are provided for managing shared expenses. The systems and methods may include a financial service provider identifying shared expenses in a customer's transaction history with software application executed on a server or personal computing device. The financial service provider may identify other individuals with whom the customer shares the expense, and send requests for reimbursement on the customer's behalf. The financial service provider may monitor the status of reimbursement payments, and send reminders as necessary until the shared expense has been reimbursed.